Structure - Activity relationships of dynorphin analogs substituted in positions 2 and 3

Biopolymers - Peptide Science Section

Volumn 71, Issue 1, 2003, Pages 71-76

  Schlechtingen, Georg ^a   DeHaven, Robert N ^b   Daubert, Jeffrey D ^b   Cassel, Joel ^b   Goodman, Murray ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ADOLOR CORPORATION   (United States)

Author keywords

agonists; antagonists; receptors; Dynorphin A

Indexed keywords

ASSAYS; CARBOXYLIC ACIDS; MEMBRANES; STRUCTURE (COMPOSITION);

OPIOID RECEPTORS;

BIOPOLYMERS;

2 AZETIDINE CARBOXYLIC ACID; AZETIDINE DERIVATIVE; DYNORPHIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE TRIPHOSPHATE; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; KAPPA OPIATE RECEPTOR ANTAGONIST; PIPERIDINE 2 CARBOXYLIC ACID; PIPERIDINE DERIVATIVE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG RECEPTOR BINDING; LIGAND BINDING; PEPTIDE SYNTHESIS; PROTEIN PURIFICATION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; DYNORPHINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); OLIGOPEPTIDES; RADIOLIGAND ASSAY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0038297574     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/bip.10382     Document Type: Article

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