Neutrophilic inflammation in induced sputum of patients with idiopathic pulmonary fibrosis

Sarcoidosis Vasculitis and Diffuse Lung Diseases

Volumn 20, Issue 2, 2003, Pages 138-143

  Beeh, Kai Michael ^a   Beier, Jutta ^a   Kornmann, Oliver ^a   Buhl, Roland ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Cytokines; Induced sputum; Neutrophils; Pulmonary fibrosis

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8;

ADULT; AGED; ARTICLE; CELL COUNT; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MARKER; FEMALE; HUMAN; INTERSTITIAL LUNG DISEASE; LUNG FIBROSIS; MALE; NEUTROPHIL; NEUTROPHILIA; PATHOGENESIS; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; SPUTUM; SUPERNATANT; VITAL CAPACITY;

ADULT; AGED; BIOLOGICAL MARKERS; CROSS-SECTIONAL STUDIES; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-8; MALE; MIDDLE AGED; NEUTROPHIL ACTIVATION; PULMONARY FIBROSIS; SPUTUM;

EID: 0038265001     PISSN: 11240490     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Crystal RG, Bitterman PB, Rennard SI, Hance AJ, Koeogh BA: Interstitial lung diseases of unknown cause: disorders characterized by chronic inflammation of the lower respiratory tract. N Engl J Med 1984; 310: 154-166 and 235-244.
2. Rochester CL, Elias JA: Cytokines and cytokine networking in the pathogenesis of interstitial and fibrotic lung disorders. Semin Respir Crit Care Med 1994; 14: 389-416.
3. King TE, Jr: Idiopathic pulmonary fibrosis. In: Schwarz MI. King TE, Jr., editors. Interstitial Lung Disease. St. Louis: Mosby, 1993: 167-403.
4. Xaubet A, Agusti C, Luburich P, Roca J, Ayuso MC, Marrades RM et al: Is it necessary to treat all patients with idiopathic pulmonary fibrosis? Sarcoidosis Vasc Diff Lung Dis 2001; 18: 289-95.
5. Phan SH: New strategies for treatment of pulmonary fibrosis. Thorax 1995; 50: 415-21.
6. Hunninghake GW, Kalica AR: Approaches to the treatment of pulmonary fibrosis. Am J Respir Crit Care Med 1995; 151: 915-8.
7. Stockley RA: Neutrophils and protease/antiprotease imbalance. Am J Respir Crit Care Med 1999; 160: S49-S52.
8. Rennard SI: Inflammation and repair processes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999; 160: S12-S16.
9. Montaldo C, Cannas E, Ledda M, Rosetti L, Congiu L, Atzori L: Bronchoalveolar glutathione and nitrit/nitrate in idiopathic pulmonary fibrosis and sarcoidosis. Sarcoidosis Vasc Diff Lung Dis 2002; 19: 54-8.
10. Schwarz MI: Treatment of IPF. What does the future hold? Chest 1995; 108: 601-2.
11. McNulty CA, Symon FA, Wardlaw AJ: Characterization of the integrin and activation steps mediating human eosinophil and neutrophil adhesion to chronically inflamed airway endothelium. Am J Respir Cell Mol Biol 1999; 20: 1251-9.
12. Adams DH, Lloyd AR: Chemokines: leucocyte recruitment and activation cytokines. Lancet 1997; 349: 490-5.
13. Mikami M, Llewellyn-Jones CG, Bayley D, Hill SL, Stockley RA: The chemotactic activity of sputum from patients with bronchiectasis. Am J Respir Crit Care Med 1998; 157: 723-8.
14. Jatakanon A, Lalloo UG, Lim S, Chung KF, Barnes PJ: Increased neutrophils and cytokines, TNF-alpha and IL-8, in induced sputum of non-asthmatic patients with dry cough. Thorax 1999; 54: 234-7.
15. Colotta F, Re F, Polenlarutti N, Sozzani S, Manlovani A: Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood 1992; 80: 2012-20.
16. Reynolds HY: Sampling local respiratory tract sites for inflammation. Sarcoidosis Vasc Diff Lung Dis 2001; 18: 138-8.
17. Fahy JV, Boushey HA, Lazarus SC, et al: Safety and reproducibility of sputum induction in asthmatic subjects in a multicenter study. Am J Respir Crit Care Med 2001; 163: 1470-5.
18. Fireman E: Induced sputum: opening a new window to the lung. Sarcoidosis Vasc Diff Lung Dis 2001; 18: 263-71.
19. Fireman Z, Osipov A, Kivity S, et al: The use of induced sputum in the assesment of pulmonary involvement in Crohn's disease. Am J Gastroenterol 2000; 95: 730-4.
20. Fireman E, Topilsky I, Greif J, et al: Induced sputum compared to bronchoalveolar lavage for evaluating patients with sarcoidosis and non-granulomatous lung disease. Respir Med 1999; 93: 827-34.
21. Tsiligianni J, Tzanakis N, Kyriakou D, Chrysofakis G, Siafakis N, Bouros D: Comparison of sputum induction with bronchoalveolar lavage cell differential counts in patients with sarcoidosis. Sarcoidosis Vasc Diff Lung Dis 2002; 19: 205-10.
22. American Thoracic Society: Idiopathic pulmonary fibrosis: diagnosis and treatment. Am J Respir Crit Care Med 2000; 161: 646-4.
23. Beeh KM, Kommann O, Lill J, Buhl R: Induced sputum cell profiles in lung transplant recipients with or without chronic rejection: correlation with lung function. Thorax 2001; 56: 557-60.
24. Gershman NH, Liu H, Wong HH, Liu JT, Fahy JV: Fractional analysis of sequential induced sputum samples during sputum induction: evidence that different lung compartments are sampled at different time points. J Allergy Clin Immunol 1999; 104: 322-8.
25. Turner-Warwick M, Haslam PL: The value of serial bronchoalveolar lavages in assessing the clinical progress of patients with cryptogenic fibrosing alveolitis. Am Rev Respir Dis 1987; 135: 26-34.
26. Crockard AD, Boylan MT, Droogan AG, McMillan SA, Hawkins SA: Methylprednisolone-induced neutrophil leukocytosis: down-modulation of neutrophil L-selectin and Mac-1 expression and induction of granulocyte-colony stimulating factor. Int J Clin Lab Res 1998; 28: 110-5.
27. Watters LC, King TE, Chemiack RM, et al: Bronchoalveolar lavage fluid neutrophils in. crease after corticosteroid therapy in smokers with idiopathic pulmonary fibrosis. Am Rev Respir Dis 1986; 133: 104-9.
28. Peterson MW, Monick M, Hunninghake GW: Prognostic role of eosinophils in pulmonary fibrosis. Chest 1987; 92: 51-6.
29. Watters LC, Schwarz MI, Cherniack RM, et al: Idiopathic pulmonary fibrosis. Pretreatment bronchoalveolar lavage cellular constituents and their relationships with lung histopathology and clinical response to therapy. Am Rev Respir Dis 1997; 135: 696-704.
30. Di Stefano A, Capelli A, Lusuardi M, et al: Severity of airflow limitiation is associated with severity of airway inflammation in smokers. Am J Respir Crit Care Med 1998; 158: 1277-85.
31. Bhowmik A, Seemungal TAR, Sapsford RJ, Wedzicha JA: Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations. Thorax 2000; 55: 114-20.
32. Yamamoto C, Yoneda T, Yoshikawa M, Fu A, et al: Airway inflammation in COPD assessed by sputum levels of interleukin-8. Chest 1997; 112: 505-10.
33. Scapini P, Lapinet-Vera JA, Gasperini S, Calzetti F, Bazzoni F, Cassatella MA: The neutrophil as cellular source of chemokines. Immunol Rev 2000; 177: 195-203.
34. Shi HZ, Chen YQ, Qin SM: Inhaled IL-5 increases concentrations of soluble intracellular adhesion molecule-1 in sputum from atopic asthmatic subjects. J Allergy Clin Immunol 1999; 103: 463-7.
35. Salva PS, Doyle NA, Graham L, Eigen H, Doerschuk CM: TNF-alpha, IL-8, soluble ICAM-1, and neutrophils in sputum of cystic fibrosis patients. Pediatr Pulmonol 1996; 21: 11-9.
36. Alexis NE, Hu SC, Zeman K, Alter T, Bennett WD: Induced sputum derives from the central airways: confirmation using a radiolabeled aerosol bolus delivery technique. Am Rev Respir Dis 2001; 164: 1964-70.
37. Shaw RJ, Djukanovic R, Tashkin DP, Millar AB, du Bois RM, Orr PA: The role of small airways in lung disease. Respir Med 2002; 96: 67-80.
38. Beeh KM, Beier J, Haas IC, Kommann O, Micke P, Buhl R: Glutathione deficiency of the lower respiratory tract in patients with idiopathic pulmonary fibrosis. Eur Respir J 2002; 19: 1119-23.
39. Cantin AM, North SL, Fells GA, Hubbard RC, Crystal RG: Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis. J Clin Invest 1987; 79: 1665-73.
40. Tiroke AH, Bewig B, Haverich A: Bronchoalveolar lavage after lung transplantation. State of the art. Clin Transplant 1999; 13: 131-57.
41. Henke JA, Golden JA, Yelin EH, Keith FA, Blanc PD: Persistent increases of BAL neutrophils as a predictor of mortality following lung transplant. Chest 1999; 115: 403-9.