The regulation of SERCA-type pumps by phospholamban and sarcolipin

Annals of the New York Academy of Sciences

Volumn 986, Issue , 2003, Pages 472-480

  MacLennan, David H ^a   Asahi, Michio ^a   Tupling, A Russell ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Ca2+ ATPase; Cardiomyopathy; Phospholamban; Regulatory molecules; Sarcolipin

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); PHOSPHOLAMBAN; PROTEIN; SARCOLIPIN; UNCLASSIFIED DRUG;

ANALYSIS; CALCIUM TRANSPORT; CONFERENCE PAPER; CONTROLLED STUDY; ELECTROSTIMULATION; EVALUATION; HEART CONTRACTION; HUMAN; HUMAN CELL; MUSCLE CONTRACTION; MUSCLE FUNCTION; MUSCLE RELAXATION; MUSCLE TETANIC CONTRACTION; MUSCLE TWITCH; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; RAT; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; SOLEUS MUSCLE;

EID: 0038239932     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2003.tb07231.x     Document Type: Conference Paper

References (24)

1. SIMMERMAN, H.K. & L.R. JONES. 1998. Phospholamban: protein structure, mechanism of action, and role in cardiac function. Physiol. Rev. 78: 921-947.
2. LUO, W. et al. 1994. Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation. Circ. Res. 75: 401-409.
3. KOSS, K.L. & E.G. KRANIAS. 1996. Phospholamban: a prominent regulator of myocardial contractility. Circ. Res. 79: 1059-1063.
4. ZVARITCH, E. et al. 2000. The transgenic expression of highly inhibitory monomeric forms of phospholamban in mouse heart impairs cardiac contractility. J. Biol. Chem. 275: 14985-14991.
5. ZHAI, J. et al. 2000. Cardiac-specific overexpression of a superinhibitory pentameric phospholamban mutant enhances inhibition of cardiac function in vivo. J. Biol. Chem. 275: 10538-10544.
6. HAGHIGHI, K. et al. 2001. Superinhibition of sarcoplasmic reticulum function by phospholamban induces cardiac contractile failure. J. Biol. Chem. 276: 24145-24152.
7. ODERMATT, A. et al. 1997. Characterization of the gene encoding human sarcolipin (SLN), a proteolipid associated with SERCA1: absence of structural mutations in five patients with Brody disease. Genomics 45: 541-553.
8. 2+-ATPase. J. Biol. Chem. 273: 12360-12369.
9. HELLSTERN, S. et al. 2001. Sarcolipin, the shorter homologue of phospholamban, forms oligomeric structures in detergent micelles and in liposomes. J. Biol. Chem. 276: 30845-30852.
10. MACLENNAN, D.H. et al. 1972. Isolation of sarcoplasmic reticulum proteins. Cold Spring Harbor Symp. Quant. Biol. 37: 469-478.
11. GAYAN-RAMIREZ, G. et al. 2000. Corticosteroids decrease mRNA levels of SERCA pumps, whereas they increase sarcolipin mRNA in the rat diaphragm. J. Physiol. 524: 387-397.
12. 2+-ATPases (SERCAs). J. Biol. Chem. 277: 26725-26728.
13. KIMURA, Y. et al. 1997. Phospholamban inhibitory function is activated by depolymerization. J. Biol. Chem. 272: 15061-15064.
14. SIMMERMAN, H.K. et al. 1996. A leucine zipper stabilizes the pentameric membrane domain of phospholamban and forms a coiled-coil pore structure. J. Biol. Chem. 271: 5941-5946.
15. 2+-ATPase isoform of cardiac sarcoplasmic reticulum. J. Biol. Chem. 273: 14238-14241.
16. 2+ ATPase isoforms and their role in muscle physiology and pathology. Ann. N. Y. Acad. Sci. 853: 251-259.
17. 2+ uptake and impairs contractile function. J. Biol. Chem. 277: 44740-44746.
18. 2+-calmodulin-dependent protein kinase. Biochim. Biophys. Acta 1464: 231-241.
19. i to the slowing of relaxation in fatigued single fibres from mouse skeletal muscle. J. Physiol. 468: 729-740.
20. ALLEN, D.G., J. LANNERGREN & H. WESTERBLAD. 1995. Muscle cell function during prolonged activity: cellular mechanisms of fatigue. Exp. Physiol. 80: 497-527.
21. WAWRZYNOW, A. et al. 1992. Sarcolipin, the "proteolipid" of skeletal muscle sarcoplasmic reticulum, is a unique, amphipathic, 31-residue peptide. Arch. Biochem. Biophys. 298: 620-623.
22. 2+-ATPase forms a functional interaction site with phospholamban: evidence for physical interactions at other sites. J. Biol. Chem. 274: 32855-32862.
23. TOYOSHIMA, C. et al. 2000. Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution. Nature 405: 647-655.
24. TOYOSHIMA, C. & H. NOMURA. 2002. Structural changes in the calcium pump accompanying the dissociation of calcium. Nature 418: 605-611.