The enhanced anti-inflammatory properties of nitro-prednisolone (NCX-1015) is linked to post-translational modification of the glucocorticoid receptor

Inflammation Research

Volumn 52, Issue SUPPL., 2003, Pages

  Paul Clark, M J ^a   Perretti, M ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; GLUCOCORTICOID RECEPTOR; NCX 1015; NITRIC OXIDE; NITROPREDNISOLONE; PREDNISOLONE 21 [4' (NITROOXYMETHYL)]BENZOATE; PREDNISOLONE DERIVATIVE; UNCLASSIFIED DRUG; NITROBENZOIC ACID DERIVATIVE; PREDNISOLONE; PREDNISOLONE 21 [4' (NITROOXYMETHYL)BENZOATE;

ANTIINFLAMMATORY ACTIVITY; BIOLOGY; CONFERENCE PAPER; CONTROLLED STUDY; ENVIRONMENT; HUMAN; HUMAN CELL; REGULATORY MECHANISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; DRUG MECHANISM; DRUG RECEPTOR BINDING; FEMALE; GOUT; MALE; MOUSE; NITRATION; NONHUMAN; PROTEIN PROCESSING; RAT; ZYMOSAN-INDUCED PERITONITIS;

EID: 0038235866     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03354220     Document Type: Conference Paper

References (9)

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8. Lanone S, Manivet P, Callebert J, Launay JM, Payen D, Aubier M, et al. Inducible nitric oxide synthase (NOS2) expressed in septic patients is nitrated on selected tyrosine residues: implications for enzymic activity. Biochem J 2002; 366: 399-404.
9. Freels JL, Nelson DK, Hoyt JC, Habib M, Numanami H, Lantz RC, et al. Enhanced activity of human IL-10 after nitration in reducing human IL-1 production by stimulated peripheral blood mononuclear cells. J Immunol 2002; 169: 4568-71.