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This paper uses a borosilicate glass microreactor, operating under electrokinetic control, to prepare stilbenes using the Wittig reaction. It discusses how the Z/E ratio of isomers changes depending on the electrokinetic parameters used.
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Skelton V., Greenway G.M., Haswell S.J., Styring P., Morgan D.O., Warrington B., Wong S.Y.F. The generation of concentration gradients using electroosmotic flow in micro reactors allowing stereoselective chemical synthesis. Analyst. 126:2001;11-13 This paper uses a borosilicate glass microreactor, operating under electrokinetic control, to prepare stilbenes using the Wittig reaction. It discusses how the Z/E ratio of isomers changes depending on the electrokinetic parameters used.
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This paper illustrates how a selection of enolates may be prepared in situ within microreactor devices. The enolates are subsequently reacted with a range of aldehydes to form a variety of aldol products in high yield.
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This paper prepares a range of Michael adducts by reaction of a selection of diketones with an organic base in a microreactor. The paper illustrates that microreactors may be used to study the kinetics of reactions.
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