A Hantzsch synthesis of 2-aminothiazoles performed in a heated microreactor system

Lab on a Chip

Volumn 2, Issue 1, 2002, Pages 31-33

  Garcia Egido, Eduardo ^a   Wong, Stephanie Y F ^a   Warrington, Brian H ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOTHIAZOLE DERIVATIVE; ACETOPHENONE;

ANALYTIC METHOD; ARTICLE; DRUG INDUSTRY; ELECTROOSMOSIS; HEATING; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; REACTION ANALYSIS; REACTOR; SAMPLING; SCREENING; TECHNIQUE;

EID: 0141961502     PISSN: 14730197     EISSN: None     Source Type: Journal    
DOI: 10.1039/b109360f     Document Type: Article

References (11)

1. H. Salimi-Moosavi, T. Tang and D. J. Harrison, J. Am. Chem. Soc., 1997, 119, 8716.
2. V. Skelton, G. M. Greenway, S. J. Haswell, P. Styring, D. O. Morgan, B. H. Warrington and S. Y. F. Wong, Analyst. 2001, 126, 11.
3. (a) P. Fletcher and S. Haswell, Chem. Br., 1999, 38;
4. (b) G. M. Greenway, S. Haswell, D. O. Morgan, V. Skelton and P. Styring, Sens. Actuators B, 2000, 63, 153.
5. M. C. Mitchell, V. Spikmans and A. J. De Mello, Analyst, 2001, 126, 24.
6. P. Watts, C. Wiles, S. J. Haswell, E. Pombo-Villar and P. Styring, Chem. Commun., 2001, 990.
7. (a) A. R. Hantzsch and J. H. Weber, Ber., 1887, 20, 3118;
8. (b) J. V. Metzger, Comprehensive Heterocyclic Chemistry, Pergamon Press Ltd., Oxford, 1st edn., 1984, vol. 6, p. 235.
9. R. N. C. Daykin and S. J. Haswell, Anal. Chim. Acta, 1995, 313, 155.
10. D. D. Perrin and W. L. F. Armarego, Purification of Laboratory Chemicals, Pergamon Press Ltd., Oxford, 3rd edn., 1988.
11. N. Bailey, A. W. Dean, D. B. Judd, D. Middlemiss, R. Storer and S. P. Watson, Bioorg. Med. Chem. Lett., 1996, 6, 1409.