Distinct tissue distribution of metabolites of the novel glutathione-activated thiopurine prodrugs cis-6-(2-acetylvlnylthio)purine and trans-6-(2-acetylvlnylthio)guaninee and 6-thioguanine in the mouse

Drug Metabolism and Disposition

Volumn 31, Issue 6, 2003, Pages 718-726

  Gunnarsdottir, Sjofn ^a   Elfarra, Adnan A ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 (2 ACETYLVINYLTHIO)GUANINE; 6 (2 ACETYLVINYLTHIO)PURINE; 6 MERCAPTOPURINE DERIVATIVE; ANTINEOPLASTIC ANTIMETABOLITE; DRUG METABOLITE; GLUTATHIONE; PRODRUG; TIOGUANINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG METABOLISM; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER CYTOSOL; MALE; METABOLITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0038193704     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.31.6.718     Document Type: Article

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