Mechanism of loading the escherichia coli DNA polymerase III β sliding clamp on DNA. Bona fide primer/templates preferentially trigger the γ complex to hydrolyze ATP and load the clamp

Journal of Biological Chemistry

Volumn 278, Issue 12, 2003, Pages 10033-10040

  Ason, Brandon ^a,d   Handayani, Renita ^a   Williams, Christopher R ^a   Bertram, Jeffrey G ^b   Hingorani, Manju M ^c,e   O'Donnell, Mike ^c   Goodman, Myron F ^b   Bloom, Linda B ^a,f  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e WESLEYAN UNIVERSITY   (United States)

^f UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; COMPLEXATION; DNA; ESCHERICHIA COLI; GENES; HYDROLYSIS; SUBSTRATES;

BINDING STATE;

ENZYME KINETICS;

ADENOSINE TRIPHOSPHATE; BACTERIAL DNA; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE GAMMA; BETA SUBUNIT, DNA POLYMERASE III; DNA; ESCHERICHIA COLI PROTEIN; HOLOENZYME; PRIMER DNA;

ANISOTROPY; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; DNA TEMPLATE; ENZYME KINETICS; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE REPLICATION; HYDROLYSIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; STEADY STATE; BINDING SITE; CHEMISTRY; ENZYMOLOGY; KINETICS; METABOLISM;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

ADENOSINE TRIPHOSPHATE; BINDING SITES; DNA; DNA POLYMERASE III; DNA PRIMERS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HOLOENZYMES; HYDROLYSIS; KINETICS; TEMPLATES, GENETIC;

EID: 0038193630     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211741200     Document Type: Article

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