Three-dimensional models of proteases involved in patterning of the drosophila embryo: Crucial role of predicted cation binding sites

Journal of Biological Chemistry

Volumn 278, Issue 13, 2003, Pages 11320-11330

  Rose, Thierry ^a   LeMosy, Ellen K ^b   Cantwell, Angelene M ^a   Banerjee Roy, Dolly ^a   Skeath, James B ^a   Di Cera, Enrico ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ENZYMES; POSITIVE IONS; RNA; SUBSTRATES;

VENTRALIZATION;

BIOCHEMISTRY;

CALCIUM ION; EASTER ZYMOGEN; ENZYME PRECURSOR; GASTRULATION DEFECTIVE ZYMOGEN; GENE PRODUCT; MESSENGER RNA; NUDEL ZYMOGEN; SERINE PROTEINASE; SNAKE ZYMOGEN; SODIUM ION; UNCLASSIFIED DRUG; CATION; DROSOPHILA PROTEIN; EASTER PROTEIN, DROSOPHILA; GASTRULATION DEFECTIVE PROTEIN, DROSOPHILA; NUDEL PROTEIN, DROSOPHILA; TRANSCRIPTION FACTOR;

ARTICLE; BINDING SITE; CATALYSIS; CATALYST; COMPLEX FORMATION; EASTER GENE; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; GASTRULATION; GASTRULATION DEFECTIVE GENE; INSECT GENETICS; NONHUMAN; NUDEL GENE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; SNAKE GENE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DROSOPHILA MELANOGASTER; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; MORPHOGENESIS; MUTATION; PHYSIOLOGY; PRENATAL DEVELOPMENT; PROTEIN CONFORMATION;

ARACHNIDA; DROSOPHILA MELANOGASTER; HEXAPODA; INSECTA; SERPENTES;

ANIMALS; BINDING SITES; BODY PATTERNING; CATALYSIS; CATIONS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; RNA, MESSENGER; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY; TRANSCRIPTION FACTORS;

EID: 0038176533     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211820200     Document Type: Article

References (44)

1. LeMosy, E. K., Hong, C. C., and Hashimoto, C. (1999) Trends Cell Biol. 9, 102-107
2. Anderson, K. V., and Nüsslein-Volhard, C. (1984) Nature 311, 223-227
3. LeMosy, E. K., Tan, Y. Q., and Hashimoto, C. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 5055-5060
4. Han, J. H., Lee, S. H., Tan, Y. Q., LeMosy, E. K., and Hashimoto, C. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 9093-9097
5. Dissing, M., Giordano, H., and DeLotto, R. (2001) EMBO J. 20, 2387-2393
6. Krem, M. M., and Di Cera, E. (2002) Trends Biochem. Sci. 27, 67-74
7. DeLotto, Y., and DeLotto, R. (1998) Mech. Dev. 72, 141-148
8. Ayala, Y. M., Cantwell, A. M., Rose, T., Bush, L. A., Arosio, D., and Di Cera, E. (2001) Proteins 45, 107-116
9. Rose, T., and Di Cera, E. (2002) J. Biol. Chem. 277, 18875-18880
10. Rose, T., and Di Cera, E. (2002) J. Biol. Chem. 277, 19243-19246
11. Sali, A., and Blundell, T. L. (1993) J. Mol. Biol. 234, 779-815
12. Berman, H. M., Westbrook, J., Feng, Z., Gilliland, G., Bhat, T. N., Weissig, H., Shindyalov, I. N., and Bourne, P. E. (2000) Nucleic Acids Res. 28, 235-242
13. Laskowski, R. A., Moss, D. S., and Thornton, J. M. (1993) J. Mol. Biol. 231, 1049-1067
14. Hooft, R. W. W., Vriend, G., Sander, C., and Abola, E. E. (1996) Nature 381, 272-272
15. Luthy, R., Bowie, J. U., and Eisenberg, D. (1992) Nature 356, 83-85
16. Nayal, M., and Di Cera, E. (1994) Proc. Natl. Acad. Sci. U. S. A. 88, 817-821
17. Pickett, S. D., and Sternberg, M. J. E. (1993) J. Mol. Biol. 231, 825-839
18. Finkelstein, A. V., and Janin, J. (1989) Protein Eng. 3, 1-3
19. Nicholls, A., Sharp, K. A., and Honig B. (1991) Proteins 11, 281-296
20. Sharp, K. A. (1998) Proteins 33, 39-48
21. Konrad, K. D., Goralski, T. J., Mahowald, A. P., and Marsh, J. L. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6819-6824
22. Chasan, R., and Anderson, K. V. (1989) Cell 56, 291-400
23. Konrad, K. D., Goralski, T. J., and Mahowald, A. P. (1988) Dev. Biol. 127, 133-142
24. Jin, Y. S., and Anderson, K. V. (1990) Cell 60, 873-881
25. Anderson, K. V., Jürgens, G., and Nüsslein-Volhard, C. (1955) Cell 42, 779-789
26. Jürgens, G., and Nüsslein-Volhard, C. (1986) in Drosophila: A Practical Approach (Roberts, D. B., ed), pp. 199-227, IRL Press at Oxford University Press, Oxford, United Kingdom
27. Willnow, T. E., Orth, K., and Herz, J. (1994) J. Biol. Chem. 269, 15827-15832
28. Nielsen, H., Engelbrecht, J., Brunak, S., and von Heijne, G. (1997) Int. J. Neural. Syst. 8, 581-599
29. DeLotto, R. (2001) EMBO Rep. 2, 721-726
30. LeMosy, E. K., Kemler, D., and Hashimoto, C. (1998) Development 125, 4045-4053
31. Schechter, I., and Berger, A. (1967) Biochem. Biophys. Res. Commun. 27, 157-162
32. Wei, A. Z., Mayr, I., and Bode, W. (1988) FEBS Lett. 234, 367-373
33. LeMosy, E. K., Leclerc, C. L., and Hashimoto, C. (2000) Genetics 154, 247-257
34. Bode, W., Turk, D., and Karshikov, A. (1992) Protein Sci. 1, 426-471
35. Arosio, D., Ayala, Y. M., and Di Cera, E. (2000) Biochemistry 39, 8095-8101
36. Di Cera, E., Guinto, E. R., Vindigni, A., Dang, Q. D., Ayala, Y. M, Wuyi, M., and Tulinsky, A. (1995) J. Biol. Chem. 270, 22089-22092
37. Ponomareff, G., Giordano, H., DeLotto, Y., and DeLotto, R. (2001) Genetics 159, 635-645
38. Guinto, E. R., Caccia, S., Rose, T., Futterer, K., Waksman, G., and Di Cera, E. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1852-1857
39. Dang, Q. D., and Di Cera, E. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 10653-10656
40. Bode, W., and Schwager, P. (1975) J. Mol. Biol. 98, 693-717
41. Mathur, A., Zhong, D., Sabharwal, A. K., Smith, K. J., and Bajaj, S. P. (1997) J. Biol. Chem. 272, 23418-23426
42. Lai, T.-S., Slaughter, T. F., Peoples, K. A., and Greenberg, C. S. (1999) J. Biol. Chem. 274, 24953-24958
43. Chang, A. J., and Morisato, D. (2002) Development 129, 5635-5645
44. Vindigni, A., and Di Cera, E. (1998) Protein Sci. 7, 1728-1737