Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) renders influenza virus-specific CD8+ T cells hyporesponsive to antigen

Toxicological Sciences

Volumn 74, Issue 1, 2003, Pages 74-84

  Mitchell, Kristen A ^a   Lawrence, B Paige ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Anergy; Antigen specific; CD8+ T lymphocytes; Immunosuppression; In vivo; Influenza virus; Lymph node; Mouse; TCDD (dioxin); Tetramer

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CD8 ANTIGEN; CYTOKINE; DRUG VEHICLE; GAMMA INTERFERON; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; RECEPTOR ANTIBODY; T LYMPHOCYTE RECEPTOR; TETRAMER; VIRUS NUCLEOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; APOPTOSIS; CELL FATE; CELL SPECIFICITY; CLONAL ANERGY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; EVIDENCE BASED MEDICINE; FEMALE; IMMUNE RESPONSE; IMMUNOSTIMULATION; IMMUNOTOXICITY; IN VIVO STUDY; INFLUENZA; INFLUENZA VIRUS; LYMPH NODE; LYMPH NODE CELL; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOLECULAR CLONING; MOUSE; NONHUMAN; POLLUTANT; REVIEW; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD8; ANTIGENS, VIRAL; APOPTOSIS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIVISION; ENVIRONMENTAL POLLUTANTS; FEMALE; FLOW CYTOMETRY; GENES, MHC CLASS I; INFLUENZA A VIRUS; INTERFERON TYPE II; LYMPH NODES; LYMPHOCYTES; MICE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; STIMULATION, CHEMICAL; TETRACHLORODIBENZODIOXIN; VIRAL CORE PROTEINS;

ANIMALIA; INFLUENZA VIRUS; RNA VIRUSES;

EID: 0038155512     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfg110     Document Type: Review

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