Characteristics of selenazolidine prodrugs of selenocysteine: Toxicity and glutathione peroxidase induction in V79 cells

Journal of Medicinal Chemistry

Volumn 46, Issue 15, 2003, Pages 3308-3313

  Short, Megan D ^a,b   Xie, Yang ^a   Li, Liang ^a   Cassidy, Pamela B ^a,c   Roberts, Jeanette C ^a  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DEXTRO SELENOCYSTINE 2 METHYLSELENAZOLIDINEN 4 CARBOXYLIC ACID; DEXTRO SELENOCYSTINE 2 OXOSELENAZOLIDINE 4 CARBOXYLIC ACID; GLUTATHIONE PEROXIDASE; ORGANOSELENIUM DERIVATIVE; SELENAZOLIDINE 4 CARBOXYLIC ACID; SELENOCYSTEINE; SODIUM SELENITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN V 79; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG SYNTHESIS; ENZYME ACTIVITY; NONHUMAN; STEREOCHEMISTRY; STEREOISOMERISM;

ANIMALS; CRICETINAE; CRICETULUS; ENZYME INDUCTION; GLUTATHIONE PEROXIDASE; ORGANOSELENIUM COMPOUNDS; PRODRUGS; PROLINE; SELENOCYSTEINE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0038155206     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020496q     Document Type: Article

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