Modifications to rat lens major intrinsic protein in selenite-induced cataract

Investigative Ophthalmology and Visual Science

Volumn 40, Issue 3, 1999, Pages 657-667

  Schey, Kevin L ^a   Fowler, John G ^a   Shearer, Thomas R ^b   David, Larry ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN; CALPAIN; MEMBRANE PROTEIN; SELENITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATARACT; CONTROLLED STUDY; ENZYME PURIFICATION; GENE TARGETING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; RAT; TANDEM MASS SPECTROMETRY; WATER PERMEABILITY;

ANIMALS; AQUAPORINS; CALPAIN; CATARACT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EYE PROTEINS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LENS, CRYSTALLINE; MEMBRANE GLYCOPROTEINS; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; PHOSPHORYLATION; RATS; SODIUM SELENITE;

EID: 0033054261     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Park JH, Saier MH Jr. Phylogenetic characterization of the MIP family of transmembrane channel proteins. J Membr Biol. 1996; 153:171-180.
2. Yang B, Verkman, AS. Water and glycerol permeabilities of aquaporins 1-5 and MIP determined quantitatively by expression of epitope-tagged constructs in Xenopus oocytes. J Biol Chem. 1997; 272:16140-16146.
3. Chandy G, Zampighi GA, Kreman M, Hall JE. Comparison of the water transporting properties of MIP and AQP1. J Membr Biol. 1997;159:29-39.
4. Michea LF, de la Fuenti M, Lagos N. Lens major intrinsic protein (MIP) promotes adhesion when reconstituted into large unilamellar liposomes. Biochem. 1994;33:7663-7669.
5. Shiels A, Bassnett S. Mutations in the founder of the MIP gene family underlie cataract development in the mouse. Nat Genet. 1996;12:212-215.
6. Ngoc LD, Paroutaud P, Dunia I, Benedetti EL, Hoebeke J. Sequence analysis of peptide fragments from the intrinsic membrane protein of calf lens fibers MP26 and its natural maturation product MP22. FEBS Lett. 1985;181:74-78.
7. Lo WK, Kuck JF. Alterations of urea-insoluble membrane fraction, MP26, of Emory mouse lenses in aging and cataractogenesis. Ophthalmic Res. 1990;22:82-88.
8. Alcala J, Unakar N, Katar M, Tsui J. Reversal of the limited proteolysis of MP26 during the reversal and prevention of the galactose cataract in rat lenses. Curr Eye Res. 1990;9:225-232.
9. Takemoto L, Takehana M. Major intrinsic polypeptide (MIP26K) from human lens membrane: characterization of low-molecular-weight forms in the aging human lens. Exp Eye Res. 1986;43:661-667.
10. Alcala J, Cenedella RJ, Katar M. Limited proteolysis of MP26 in lens fiber plasma membranes of the U18666A-induced cataract in rats. Curr Eye Res. 1985;4:1001-1005.
11. Mitton KP, Kamiya T, Tumminia SJ, Russell P. Cysteine protease activated by expression of HIV-1 protease in transgenic mice. MIP26 (aquaporin-0) cleavage and cataract formation in vivo and ex vivo. J Biol Chem. 1996;271:31803-31806.
12. David LL, Takemoto LJ, Anderson RS, Shearer TR. Proteolytic changes in main intrinsic polypeptide (MIP26) from membranes in selenite cataract. Curr Eye Res. 1988;7:411-417.
13. Peracchia C, Girsch SJ. Is the C-terminal arm of lens gap junction channel protein the channel gate? Biochem Biophys Res Commun. 1985;133:688-695.
14. Schey KL, Fowler J, Schwartz JC, Busman M, Dillon J, Crouch RK. Complete map and identification of the phosphorylation site of bovine lens major intrinsic protein. Invest Ophthalmol Vis Sci. 1997;38:2508-2515.
15. Ehring GR, Lagos N, Zampighi GA, Hall JE. Phosphorylation modulates the voltage dependence of channels reconstituted from the major intrinsic protein of lens fiber membranes. J Membr Biol. 1992;126:75-88.
16. David LL, Azuma M, Shearer TR. Cataract and the acceleration of calpain-induced beta-crystallin insolubilization occurring during normal maturation of rat lens. Invest Ophthalmol Vis Sci. 1994; 35:785-793.
17. David LL, Shearer TR. Calcium-activated proteolysis in the lens nucleus during selenite cataractogenesis. Invest Ophthalmol Vis Sci. 1984;25:1275-1283.
18. David LL, Shearer TR. Purification of calpain II from rat lens and determination of endogenous substrates. Exp Eye Res. 1986;42: 227-238.
19. Shearer TR, Ma H, Fukiage C, Azuma M. Selenite nuclear cataract: review of the model. Molec Vis. Available at http://www.emo-ry.edu/molvis/v3/shearer.
20. Russell P, Robison WG Jr, Kinoshita JH. A new method for rapid isolation of the intrinsic membrane proteins from lens. Exp Eye Res. 1981;32:511-516.
21. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227:680-685.
22. Ball LE, Oatis JE Jr, Dharmasiri K, et al. Mass spectrometric analysis of integral membrane proteins: application to complete mapping of bacteriorhodopsins and rhodopsin. Protein Sci. 1998;7:758-764.
23. David LL, Shearer TR, Shih M. Sequence analysis of lens beta-crystallins suggests involvement of calpain in cataract formation. J Biol Chem. 1993;268:1937-1940.
24. David LL, Shearer TR. Beta-crystallins insolubilized by calpain II in vitro contain cleavage sites similar to beta-crystallins insolubilized during cataract. FEBS Lett. 1993;324:265-270.
25. David LL, Wright JW, Shearer TR. Calpain II induced insolubilization of lens beta-crystallin polypeptides may induce cataract. Biochim Biophys Acta. 1992;1139:210-216
26. Lampe PD, Johnson RG. Amino acid sequence of in vivo phosphorylation sites in the main intrinsic protein (MIP) of lens membranes. Eur J Biochem. 1990;194:541-547.
27. Alcala J, Putt D, Maisel H. Limited proteolysis of gap junction protein is intrinsic in mammalian lens fiber-cell plasma membranes. Biochem Biophys Res Commun. 1987;147:846-853.
28. Srivastava OP. Characterization of a highly purified membrane proteinase from bovine lens. Exp Eye Res. 1988;46:269-283.
29. Srivastava OP, Srivastava K. Human lens membrane proteinase: purification and age-related distributional changes in the water-soluble and insoluble protein fractions. Exp Eye Res. 1989;48:161-175.
30. Ma H, Fukiage C, Azuma M, Shearer TR. Protein for Lp82 calpain is expressed and enzymatically active in young rat lens. Exp Eye Res. 1998;67:221-229.
31. Gorin MB Yancey SB, Cline J, Revel JP, Horwitz J. The major intrinsic protein (MIP) of the bovine lens fiber membrane: characterization and structure based on cDNA cloning. Cell. 1984;39: 49-59.
32. Palmquist B-M, Fagerholm P, Landau I. Selenium-induced cataract: a correlation of dry mass content and light scattering. Exp Eye Res. 1986;42:35-42.
33. Shearer TR, Anderson RS. Histologic changes during selenite cataractogenesis: a light microscopy study, Exp Eye Res. 1985;40: 557-565.
34. Matsushima H, David L, Hiraoka T, Clark JI. Loss of cytoskeletal proteins and lens cell opacification in the selenite cataract model. Exp Eye Res. 1997;64:387-395.
35. Steele EC Jr, Kerscher S, Lyon MF, et al. Identification of a mutation in the MPI9 gene, Lim2, in the cataractous mouse mutant To3. Molec Vis. Available at http://www.emory.edu/ molvis/v3/steele.