Non-alcoholic steatohepatitis - A new clinicopathological hepatic disorder;Nonalkoholisk steatohepatitis - En »ny« sygdom i hepatologien

Ugeskrift for Laeger

Volumn 165, Issue 11, 2003, Pages 1115-1118

  Grøenbæk, Henning ^a   Eivindson, Martin V ^a   Hamilton Dutoit, Stephen ^a   Vilstrup, Hendrik ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

DIET THERAPY; EXERCISE; HEALTH CARE SYSTEM; HUMAN; HYPERTENSION; INSULIN RESISTANCE; LIPID STORAGE; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER DISEASE; LIVER FAILURE; LIVER FIBROSIS; LIVER TRANSPLANTATION; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; OBESITY; REVIEW; WEIGHT REDUCTION; DENMARK; FATTY LIVER; HEPATITIS; LIVER; PATHOLOGY;

DENMARK; FATTY LIVER; HEPATITIS; HUMANS; LIVER;

EID: 0038146868     PISSN: 00415782     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (36)

1. Ludwig J, Viggiano TR, McGill DB et al. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980;55:434-48.
2. Brunt EM. Nonalcoholic steatohepatitis: definition and pathology. Semin Liver Dis 2001;21:3-16.
3. Reid AE. Nonalcoholic steatohepatitis. Gastroenterology 2001;121: 710-23.
4. Kumar KS, Malet PF. Nonalcoholic steatohepatitis. Mayo Clin Proc 2000; 75:733-79.
5. Chitturi S, Farrell GC. Etiopathogenesis of nonalcoholic steatohepatitis. Semin Liver Dis 2001;21:27-41.
6. Lonardo A. Fatty liver and nonalcoholic steatohepatitis. Where do we stand and where are we going? Dig Dis 1999;17:80-9.
7. Byron D, Minuk GY. Clinical hepatology: profile of an urban, hospital-based practice. Hepatology 1996;24:813-85.
8. Wanless IR, Lentz JS. Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors. Hepatology 1990;12:1106-10.
9. Angulo P, Keach JC, Batts KP et al. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology 1999;30:1356-62.
10. Matteoni CA, Younossi ZM, Gramlich T et al. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999;116:1413-9.
11. Lee RG. Nonalcoholic steatohepatitis: a study of 49 patients. Hum Pathol 1989;20:594-8.
12. Powell EE, Cooksley WG, Hanson R et al. The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years. Hepatology 1990;11:74-80.
13. Caldwell SH, Oelsner DH, Iezzoni JC et al. Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease. Hepatology 1999; 29:664-9.
14. Lander O, Heitmannn BL, Raben A et al. Fedme i Danmark. Ugeskr Læger 2001; 163 (suppl 8):1-20.
15. Jepsen P, Vilstrup H, Mellemkjær L et al. Prognosis of patients with a diagnosis of fatty liver - a registry-based cohort study. Hepatogastroenterology 2003 (i trykken).
16. Sørensen HT, Thulstrup A, Mellemkjær L et al. Long-term survival and cause-specific mortality in patients with cirrhosis of the liver, a nationwide cohort-study in Denmark. J Clin Epidemiol 2003 (i trykken).
17. Ratziu V, Giral P, Charlotte F et al. Liver fibrosis in overweight patients. Gastroenterology 2000;118:1117-23.
18. Dixon JB, Bhathal PS, O'Brien PE. Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. Gastroenterology 2001;121:91-100.
19. Marchesini G, Brizi M, Bianchi G et al. Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes 2001;50:1844-50.
20. Marchesini G, Brizi M, Morselli-Labate AM et al. Association of nonalcoholic fatty liver disease with insulin resistance. Am J Med 1999;107: 450-5.
21. Sanyal AJ, Campbell-Sargent C, Mirshahi F et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001;120:1183-92.
22. Weltman MD, Farrell GC, Liddle C. Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation. Gastroenterology 1996;111:1645-53.
23. Weltman MD, Farrell GC, Hall P et al. Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis. Hepatology 1998; 27:128-33.
24. Cortez-Pinto H, Chatham J, Chacko VP et al. Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study. JAMA 1999;282:1659-64.
25. Yang SQ, Lin HZ, Lane MD et al. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc Natl Acad Sci USA 1997;94:2557-262.
26. Matthews DR, Hosker JP, Rudenski AS et al. Homeostasis model assessment: insulin resistance and -cell function from plasma fasting glucose and insulin concentrations in man. Diabetologia 1985;28:412-9.
27. Day CR. Non-alcoholic steatohepatitis (NASH): where are we and where are we going? Gut 2002;50:585-8.
28. Vajro P, Fontanella A, Perna C et al. Persistent hyperaminotransferasemia resolving after weight reduction in obese children. J Pediatr 1994; 125: 239-41.
29. Knobler H, Schatmer A, Zhornicki T et al. Fatty liver - an additional and treatable feature of the insulin resistance syndrome. QJM 1999;92:73-9.
30. Laurin J, Lindor KD, Crippin JS et al. Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: a pilot study. Hepatology 1996;23:1464-7.
31. Basaranoglu M, Acbay O, Sonsuz A. A controlled trial of gemfibrozil in the treatment of patients with nonalcoholic steatohepatitis. J Hepatol 1999;31:384.
32. Abdelmalek MF, Angulo P, Jorgensen RA et al. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;97:2711-7.
33. Lavine JE. Vitamin E treatment of nonalcoholic steatohepatitis in children: a pilot study. J Pediatr 2000;136:734-78.
34. Hasegawa T, Yoneda M, Nakamura K et al. Plasma transforming growth factor-1 level and efficacy of -tocopherol in patients with non-alcoholic steatohepatitis: a pilot study. Aliment Pharmacol Ther 2001;15:1667-72.
35. Caldwell SH, Hespenheide EE, Redick JA et al. A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis. Am J Gastroenterol 2001;96:519-25.
36. Marchesini G, Brizi M, Bianchi G et al. Metformin in non-alcoholic steatohepatitis. Lancet 2001;358:893-4.