Antibodies to neuronal targets in neurological and psychiatric diseases

Annals of the New York Academy of Sciences

Volumn 992, Issue , 2003, Pages 48-55

  Vincent, Angela ^a   Dalton, Paola ^a   Clover, Linda ^a   Palace, Jackie ^a   Lang, Bethan ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Arthrogryposis multiplex congenita; Autism; Fetal acetylcholine receptor; Lambert Eaton myasthenic syndrome; Limbic syndromes; Myasthenia gravis; Neuromyotonia

Indexed keywords

ANTIBODY; CHOLINERGIC RECEPTOR; ION CHANNEL; MATERNAL ANTIBODY;

ANTIBODY DETECTION; ARTHROGRYPOSIS; AUTISM; CENTRAL NERVOUS SYSTEM DISEASE; CHANNEL GATING; CONFERENCE PAPER; EATON LAMBERT SYNDROME; HUMAN; LIMBIC SYSTEM; MENTAL DISEASE; MYASTHENIA GRAVIS; MYOKYMIA; NERVE CELL DIFFERENTIATION; NEUROLOGIC DISEASE; NEUROMUSCULAR SYNAPSE; NEUROMUSCULAR TRANSMISSION; NEUROPATHOLOGY;

EID: 0038129499     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2003.tb03137.x     Document Type: Conference Paper

References (32)

1. DRACHMAN, D.B. 1994. Myasthenia gravis. N. Engl. J. Med. 330: 1797-1810.
2. VINCENT, A., J. PALACE & D. HILTON-JONES. 2001. Myasthenia gravis. Semin. Lancet 357: 2122-2128.
3. LINDSTROM, J.M., M.E. SEYBOLD, V.A. LENNON, et al. 1976. Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic value. Neurology 26: 1054-1059.
4. NEWSOM-DAVIS, J., A.J. PINCHING, A. VINCENT & S.G. WILSON. 1978. Function of circulating antibody to acetylcholine receptor in myasthenia gravis: investigation by plasma exchange. Neurology 28: 266-272.
5. TOYKA, K.V., D.B. DRACHMAN, D.E. GRIFFIN, et al. 1977. Myasthenia gravis: study of humoral immune mechanisms by passive transfer to mice. N. Engl. J. Med. 296: 25-131.
6. ENGEL, A.G. 1984. Myasthenia gravis and myasthenic syndromes. Ann. Neurol. 16: 519-534.
7. PATRICK, J. & J. LINDSTROM. 1973. Autoimmune response to acetylcholine receptor. Science 180: 871-872.
8. VINCENT, A. 2002. Measuring and evaluating the significance of autoantibodies in neurological disorders. Clin. Allergy Immunol. Rev. 3: 127-151.
9. TZARTOS, S.J., T. BARKAS, M.T. CUNG, et al. 1998. Anatomy of the antigenic structure of a large membrane autoantigen, the muscle-type nicotinic acetylcholine receptor. Immunol Rev. 163: 89-120.
10. HOCH, W., J. MCCONVILLE, S. HELMS, et al. 2001. Autoantibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat. Med. 7: 365-368.
11. POLIZZI, A., S.M. HUSON & A. VINCENT. 2000. Teratogen update: maternal myasthenia gravis as a cause of congenital arthrogryposis. Teratology 62: 332-341.
12. HALL, J. & A. VINCENT. 2001. Arthrogryposis. In Handbook of Muscle Diseases of Childhood. R. Jones & B. Darras, Eds. Elsevier Science (USA). Burlington, MA.
13. VINCENT, A., C. NEWLAND, L. BRUETON, et al. 1995. Arthrogryposis multiplex congenita with maternal autoantibodies specific for a fetal antigen. Lancet 346: 24-25.
14. BRUETON, L.A. et al. 2000 Asymptomatic maternal myasthenia as a cause of the Pena-Shokeir phenotype. Am. J. Med. Genet. 92: 1-6.
15. JACOBSON, L., A. POLIZZI, G.M. MORRISS-KAY & A. VINCENT. 1999. An animal model of antibody-mediated neurodevelopmental disease: arythrogryposis multiplex congenita caused by antibodies to fetal acetylcholine receptor. J. Clin. Invest. 103: 1031-1038.
16. LANG, B., J. NEWSOM-DAVIS, C. PRIOR & D. WRAY. 1983. Antibodies to motor nerve terminals: an electrophysiological study of a human myasthenic syndrome transferred to mouse. J. Physiol. 344: 335-345.
17. VINCENT, A., B. LANG & J. NEWSOM-DAVIS. 1989. Autoimmunity to the voltage-gated calcium channel underlies the Lambert-Eaton myasthenic syndrome, a paraneoplastic disorder. Trends Neurosci. 12: 496-502.
18. WATERMAN, S.A., B. LANG & J. NEWSOM-DAVIS. 1997. Effect of Lambert-Eaton myasthenic syndrome antibodies on autonomic neurons in the mouse. Ann. Neurol. 42: 147-156.
19. NEWSOM-DAVIS, J. & K.R. MILLS. 1993. Immunological associations of acquired neuromyotonia (Isaacs' syndrome). Report of five cases and literature review. Brain 116: 453-469.
20. SHILLITO, P., P.C. MOLENAAR, A. VINCENT, et al. 1995. Acquired neuromyotonia: evidence for autoantibodies against K+ channels of peripheral nerves. Ann. Neurol. 38: 714-722.
21. LENNON, V.A., T.J. KRYZER, G.E. GRIESMANN, et al. 1995. Calcium-channel antibodies in the Lambert-Eaton syndrome and other paraneolastic syndromes. N. Engl. J. Med. 332: 1467-1474.
22. GRAUS, F., B. LANG, P. POZO-ROSICH, et al. 2002. P/Q type calcium channel antibodies in paraneoplastic cerebellar degeneration with lung cancer. Neurology 59: 764-766.
23. BUCKLEY, C., J. OGER, L. CLOVER, et al. 2001. Potassium channel antibodies in two patients with reversible limbic encephalitis. Ann. Neurol. 50: 74-79.
24. LIGUORI, R., A. VINCENT, L. CLOVER, et al. 2001 Morvan's syndrome: peripheral and central nervous system and cardiac involvement with antibodies to voltage-gated potassium channels. Brain 124: 2417-2426.
25. VINCENT, A., R. DEACON, P. DALTON, et al. 2002. Maternal antibody-mediated dyslexia? Evidence for a pathogenic serum factor in a mother of two dyslexic children shown by transfer to mice using behavioural studies and magnetic resonance spectroscopy. J. NeuroImmunol. 130: 243-247.
26. POUSTKA, F. 1998. Neurobiology of autism. In Autism and Pervasive Developmental Disorders. F.R. Volkmar, Ed. :130-168. Cambridge Monographs in Child and Adolescent Psychiatry. Cambridge, UK.
27. ADINOLFI, M. 1993 Fetal exposure to maternal brain antibodies and neurological handicap. In Dyslexia and Development. A.M. Galaburda, Ed. :155-167. Harvard University Press. Cambridge, MA
28. WARREN, R.P., P. COLE, J.D. ODELL, et al. 1990. Detection of maternal antibodies in infantile autism. J. Am. Acad. Child Adolesc. Psychiatry 29: 873-877.
29. DALTON, P., R. DEACON, A.M. BLAMIRE, et al. 2003. Experimental evidence for a feto-pathogenic antibody in the mother of children with autism and a severe speech disorder. Ann. Neurol. 53: 533-537.
30. CRAWLEY, J.N. 2000. What's Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice. Wiley-Liss. New York.
31. GUENTHER, K., R.M. DEACON, V.H. PERRY & J.N. RAWLINS. 2001. Early behavioural changes in scrapie-affected mice and the influence of dapsone. Eur. J. Neurosci. 14: 401-409.
32. DEACON, R.M.J., D.M. BANNERMAN, B.P. KIRBY, et al. 2002. Effects of cytotoxic hippocampal lesions in mice on a cognitive test battery. Behav. Brain Res. 133: 57-68.