Treatment of hyperhomocyst(e)inemia: Physiological basis

Journal of Nutrition

Volumn 126, Issue 4 SUPPL., 1996, Pages

  Kang, Soo Sang ^a,b  

^a RUSH MEDICAL COLLEGE   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

genetic factor; homocystinuria; hyperhomocyst(e)inemia; nongenetic factor; treatment

Indexed keywords

HOMOCYSTINE;

AMINO ACID METABOLISM; CONFERENCE PAPER; DISEASE SEVERITY; DRUG BLOOD LEVEL; ENZYME ACTIVITY; ENZYME DEFICIENCY; HEREDITY; HOMOCYSTINURIA; HUMAN; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PHYSIOLOGY; TURNOVER TIME;

EID: 0029995347     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/126.suppl_4.1273s     Document Type: Conference Paper

References (7)

1. Dudman, N. P. B., Kim, M. H., Wang, J., Wong, P. W. K., Wilcken, D. E. L., Marshall, M. D. & Kang, S. S. (1993) Thermolabile methylenetetrahydrofolate reductase Causes hyperhomocyst(e)inemia in patients with vascular disease. Am. J. Hum. Genet. 53: 899 (abs.).
2. Kang, S. S., Wong, P. W. K., Bock, H. O., Horwitz, A. & Grix, A. (1991) Intermediate hyperhomocysteinemia resulting from compound heterozygosity of methylenetetrahydrofolate reductase mutations. Am. J. Hum. Genet. 48: 546-551.
3. Kang, S. S., Wong, P. W. K. & Malinow. (1992) Hyperhomocyst(e)inemia as a risk factor for occlusive vascular disease. Annu. Rev. Nutr. 12: 279-298.
4. Kang, S. S., Wong, P. W. K. & Norusis, M. (1987) Homocysteinemia due to folate deficiency. Metabolism 36: 458-462.
5. Mudd, S. H., Levy, H. L. & Skovy, F. (1995) Disorders of transsulfuration. In: The Metabolic and Molecular Bases of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S. & Valle, D., ed.), pp. 1279-1238. McGraw Hill, New York, NY.
6. Ueland, P. M. & Refsum, H. (1989) Plasma homocysteine, a risk factor for vascular disease, and drug therapy. J. Lab. Clin. Med. 114: 473-501.
7. Ueland, P. M., Refsum, H., Stabler, S. P., Malinow, M. R., Andersson, A. & Allen, R. H. (1993) Total homocysteine in plasma or serum: methods and clinical applications. Clin. Chem. 39: 1764-1779.