Glucuronoxylomannan of Cryptococcus neoformans exacerbates in vitro yeast cell growth by interleukin 10-dependent inhibition of CD4+ T lymphocyte responses

Cellular Immunology

Volumn 222, Issue 2, 2003, Pages 116-125

  Andrade, Regis Mariano ^a   Almeida, Geisy Monteiro ^a   DosReis, George Alexandre ^a   Bento, Cleonice Alves Melo ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Cryptococcus neoformans; Glucuronoxylomanannan; Th1 and Th2 phenotype

Indexed keywords

CD4 ANTIGEN; CYTOKINE; GAMMA INTERFERON; GLUCURONOXYLOMANNAN; INTERLEUKIN 10; INTERLEUKIN 4; MANNAN; NEUTRALIZING ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOHYDRATE ANALYSIS; CELL ASSAY; CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CELL STIMULATION; CRYPTOCOCCUS NEOFORMANS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; FUNGAL STRAIN; FUNGUS GROWTH; HOST; IMMUNE RESPONSE; IN VITRO STUDY; INFECTION; INFLAMMATION; LYMPHOCYTE PROLIFERATION; MALE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; SPLEEN CELL; T LYMPHOCYTE; YEAST; YEAST CELL;

FILOBASIDIELLA NEOFORMANS; FUNGI; MURINAE;

EID: 0038121652     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-8749(03)00116-3     Document Type: Article

References (48)

1. Chuck S.L., Sande M.A. Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome. New Engl. J. Med. 321:1989;794-801.
2. + T Cell cause multinucleated giant cells to form around Cryptococcus neoformans and confine the yeast within the primary site of infection in the respiratory tract. J. Exp. Med. 175:1992;1685-1695.
3. + T cells. J. Exp. Med. 173:1991;755-758.
4. + T cells. J. Exp. Med. 173:1991;793-806.
5. Mody C.H., Paine R., Jackson C., Chen G.H., Toews G.B. CD8 cells play a critical role in delayed type hypersensitivity to intact Cryptococcus neoformans. J. Immunol. 152:1994;3970-3979.
6. + T cell-dependent acquired state of immunity that protects the brain against Cryptococcus neoformans. J. Immunol. 152:1994;2344-5230.
7. Buchanan K.L., Murphy J.W. Characterization of cellular infiltrates and cytokine production during the expression phase of the anti-cryptococcal delayed-type hypersensitivity response. Infect. Immun. 61:1993;2854-2865.
8. Buchanan K.L., Murphy J.W. Regulation of cytokine production during the expression phase of the anticryptococcal delayed-type hypersensitivity response. Infect. Immun. 62:1994;2930-2939.
9. Aguirre K., Havell E.A., Gibson G., Johnson L. Role of tumor necrosis factor and interferon γ in acquired resistance to Cryptococcus neoformans in the central nervous system of mice. Infect. Immun. 63:1995;1725-1731.
10. Hoag K.A., Lipscomb M.E., Izzo A.A., Street N.E. IL-12 and IFN-γ are required for initiating the protective Th1 response to pulmonary cryptococcosis in resistant C.B-17. Am. J. Resp. Cell Mol. Biol. 13:1997;733-7339.
11. Huffnagle G.B., Toews G.B., Burdick M.D. Afferent phase production of TNF-α is required for the development of protective T cell immunity to Cryptococcus neoformans. J. Immunol. 157:1996;4529-4538.
12. Kawakami K., Tohyama M., Xie Q., Saito A. IL-12 protects mice against pulmonary and disseminated infection caused by Cryptococuus neoformans. Clin. Exp. Immunol. 104:1996;208-214.
13. Levitz S.M., Tabumi A., Kornfeld H., Reardon C., Golenbock D.T. Production of tumor necrosis factor α in human leukocytes stimulated by Cryptococcus neoformans. Infect. Immun. 62:1994;1975-1982.
14. Lortholary O., Improvisi L., Fitting C., Cavaillon J.M., Drover F. Influence of gender and age on course of infection and cytokine responses in mice with disseminated Cryptococcus neoformans infection. Clin. Microbiol. Infection. 8(1):2002;31-37.
15. Qureshi M.H., Zhang T., Koguchi Y., Nakashima K., Okamura H., Kurimoto, Kawakami K. Combined effects of IL-12 and Il-18 on the clinical course and local cytokine production in murine pulmonary infection with Cryptococcus neoformans. Eur. J. Immunol. 29:1999;643-649.
16. Kawakami K., Koguchi Y., Querishi M.H., Myazato A., Yara S., Kirjo Y., Iwakura Y. IL-18 contributes to host resistance against infection with Cryptococcus neoformans in mice with defective IL-12 syntheis through induction of IFN-γ production by NK cells. J. Immunol. 165:2000;941-947.
17. Abe K., Kadota J.-I., Ishimatsu Y., Iwashita T., Tomono K., Kawakami K., Kohno S. Th1-Th2 cytokine kinetics in the broncoalveolar lavage fluid of mice infected with Cryptococcus neoformans of different virulences. Microbiol. Immunol. 44(10):2000;849-855.
18. Traynor T.R., Kuziel W.A., Toews G.B., Huffnagle G.B. CCR2 expression determines T1 versus T2 polarization during pulmonary Cryptococcus neoformans infection. J. Immunol. 164(4):2000;2021-2027.
19. Bolanos B., Mitchell T.G. Phagocytosis and killing of Cryptococcus neoformans by rat alveolar macrophages in the absence of serum. J. Leukoc. Biol. 46:1989;521-528.
20. Collins H., Bancroft L.J. Encapsulation of Cryptococcus neoformans impairs antigen-specific T-cell responses. Infect. Immun. 59:1991;3883-3888.
21. Vecchiarelli A., Pietrella D., Dottorine M., Monari C., Retini C., Todisco T., Bistoni F. Encapsulation of Cryptococcus neoformans regulates fungicidal activity and the antigen presentation process in human alveolar macrophages. Clin. Exp. Immunol. 89:1994;217-223.
22. Murphy J.W. Cytokine profiles associated with induction of the anticryptococcal cell mediated immune response. Infect. Immun. 61:1993;4750-4759.
23. Cross C.E., Bancroft G.J. Ingestion of acapsular Cryptococcus neoformans occurs via mannose and β-glucan receptors, resulting in cytokine production and increased phagocytosis of the encapsulated form. Infect. Immun. 63:1995;2604-2611.
24. Dykstra M., Friedman L., Murphy J.W. Capsule size of Cryptococcus neoformans: control and relationship to virulence. Infect. Immun. 16:1977;129-135.
25. Wilder J.A., Olson G.K., Chang Y.C., Kwon-Chung K.J., Lipscomb M.F. Complementation of capsule deficient Cryptococcus neoformans with CAP 64 restores virulence in a murine lung infection. Am. J. Respir. Cell Mol. Biol. 26(3):2002;306-312.
26. Bhattacharjee A.K., Bennett J.E., Glaucemans C.P.J. Capsular polysaccharides of Cryptococcus neoformans. Rev. Infect. Dis. 6:1984;619-624.
27. Chiapello L., Iribarren P., Cervi L., Rubstein H., Masih O.T. Mechanisms of induction of immunosupression during experimental cryptococcosis: role of gucuronoxylomannan. Clin. Immunol. 100(1):2001;96-106.
28. Kozel T.R. Non-encapsulated variant of Cryptococcus neoformans II. Surface receptors for cryptococcal polysaccharide and their role in inhibition of phagocytosis by polysaccharide. Infect. Immun. 16:1977;99-106.
29. Kozel T.R., Hermerath C.A. Binding of cryptococcal polysaccharide to Cryptococcus neoformans. Infect. Immun. 43:1984;879-886.
30. Retine C., Casadevall A., Pietrella D., Monari C., Palazzetti B., Vecchiarelli A. Specific activated T cells regulate IL-12 production by human monocytes stimulated with Cryptococcus neoformans. J. Immunol. 162:1999;1618-1623.
31. Retini C., Kozel T.R., Pitrella O., Monari C., Bistoni F., Vecchiarelli A. Interdependency of interleukin-10 and interleukin-12 in regulation of T-cell differentiation and effector function of monocytes in response to stimulation with Cryptococcus neoformans. Infect. Immun. 69(10):2001;6064-6073.
32. Vecchiarelli A., Retini C., Monari C., Taschini C., Bistoni F., Kozel T.R. Purified capsular polysaccharide of Cryptococcus neoformans induces interleukin-10 secretion by human manocytes. Infect. Immun. 64:1996;2846-2849.
33. Syme R.M., Bruno T.F., Kozel T.R., Mody C.H. The capsule of Cryptococcus neoformans reduces T-lymphocytes proliferation by reducing phagocytosis, which can be restored with anticapsular antibody. Infect. Immun. 67:1999;4620-4627.
34. Feldmesser M., Tucker S., Casadevall A. Intracellular parasitism of macrophages by Cryptococcus neoformans. Trends Microbiol. 9:2001;273-278.
35. Monari C., Kozel T.R., Casadevall A., Pietrella D., Palazzetti B. B7 costimulatory ligand regulates development of the T-cell response to Cryptococcus neoformans. Immunology. 98:1999;27-35.
36. + T cells in dominant Th2 pattern. J. Immunol. 167:2001;5845-5851.
37. Jacobson E.S., Ayers D.J., Harrel A.C., Nicholas C.C. Genetic and phenotypic characterization of capsule mutants of Cryptococcus neoformans. J. Bacteriol. 150:1982;1292-1296.
38. Cherniak R., Reiss E., Turner S.H. A galactoxylomannan antigen of Cryptococcus neoformans serotype A. Carbohydr. Res. 103:1982;239-520.
39. Lloyd K.O., Bitoon M.A. Isolation and purification of a peptide-rhamnomannan from the yeast form of Sporothrix schenckii: structural and immunological studies. J. Immunol. 107:1971;668-674.
40. Casadevall A., Perfect J.R. Human cryptococcosis. Casadevall A., Perfect J.R. Cryptococcus neoformans. 1999;407-456 American Society for Microbiology Press, Washington, DC.
41. Karandikar N.J., Vanderlugt C.L., Eagar T., Tan L., Bluestone J.A., Miller S.D. Tissue specific upregulation of B7.1 expression and function during course of murine relapsing experimental autoimmune encephalomyelitis. J. Immunol. 161:1998;192-198.
42. Blackstock R., McElwee N., Neller E., Shaddix-White J. Regulation of cytokine expression in mice immunized with cryptococcal polysaccharide, a glucoronoxylomannan (GXM), associated with peritoneal antigen-presenting cells (APC): requirements for GXM, APC activation, and interleukin-12. Infect. Immun. 68(9):2000;5146-5153.
43. + T cells promptly produce interleukin-4 in response to in vivo challenge with anti-CD3. J. Exp. Med. 179:1994;1285-1296.
44. Lovchik J., Lyon C.R., Lipscomb M. A role for γ interferon-induced nitric oxide in pulmonary clearance of Cryptococcus neoformans. Am. J. Resp. Cell Mol. Biol. 13:1995;116-124.
45. Fiorentino D.F., Bond M.W., Mosmann T.R. Two types of mouse T helper cell clones. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. 170:1989;2081-2090.
46. Finkelman F.D., Holmes J., Katna I.M. Lymphokine control of in vivo immunoglobulin isotype selection. Annu. Rev. Immunol. 8:1990;303-309.
47. Blackstock R., Buchanan K.L., Adesina A.M., Murphy J.W. Differential regulation of immune responses by highly and weakly virulent Cryptococcus neoformnas isolates. Infect. Immun. 67:1999;3601-3609.
48. Rubstein H.R., Sotomayer C.E., Cervil L.A., Riviera C.M., Marish D.T. Modulation of I-A and I-E expression in macrophages by T suppressor cells induced in Cryptococcus neoformans infected rats. Mycopathology. 123:1993;141-148.