Th1-Th2 cytokine kinetics in the bronchoalveolar lavage fluid of mice infected with Cryptococcus neoformans of different virulences

Microbiology and Immunology

Volumn 44, Issue 10, 2000, Pages 849-855

  Abe, Koh ^a   Kadota, Jun Ichi ^a   Ishimatsu, Yuji ^a   Iwashita, Tetsuji ^a   Tomono, Kazunori ^a   Kawakami, Kazuyoshi ^b   Kohno, Shigeru ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

Bronchoalveolar lavage; Cryptococcus neoformans; Cytokines; Virulence

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; CYTOKINE PRODUCTION; HOST RESISTANCE; INFLAMMATORY CELL; LEUKOCYTE COUNT; LUNG LAVAGE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; SPECIES DIFFERENCE; SURVIVAL; VIRULENCE;

ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; COLONY COUNT, MICROBIAL; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; CYTOKINES; DISEASE MODELS, ANIMAL; HUMAN; KINETICS; LEUKOCYTE COUNT; MALE; MICE; MICE, INBRED BALB C; TH1 CELLS; TH2 CELLS; VIRULENCE;

EID: 0033787991     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2000.tb02573.x     Document Type: Article

References (43)

1. Secretion of the C3 component of complement by peritoneal cells cultured with encapsulated Cryptococcus neoformans
2. Cryptococcus neoformarts. II. Phagocytosis by human leukocytes
3. Th1 and Th2 cytokines in mice with invasive aspergillosis
4. Experimental murine pulmonary cryptococcosis. Differences in pulmonary inflammation and lymphocyte recruitment induced by two encapsulated strains of Cryptococcus neoformans
5. Factors influencing killing of Cryptococcus neoformans by human leukocytes in vitro
6. Mobility of human neutrophils in response to Cryptococcus neoformans cells, culture filtrate antigen, and individual components of the antigen
7. Early gamma interferon production by natural killer cells is important in defence against murine listeriosis
8. Capsule size of Cryptococcus neoformans: Control and relationship to virulence
9. Microevolution of a standard strain of Cryptococcus neoformans resulting in differences in virulence and other phenotyes
10. Natural host resistance to infection with Cryptococcus neoformans. V. The influence of cationic tissue proteins upon phagocytosis and on circulating antibody synthesis
11. Natural cellular resistance of beige mice against Cryptococcus neoformans
12. Development of Th1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
13. Immunity to a pulmonary Cryptococcus neoformans infection required both CD4+ and CD8+ T cells
14. Characterization of a phenol oxidase from Cryptococcus neoformans
15. The interaction of phagocytosis and the large-sized parasite Cryptococcus neoformans: Cytochemical and ultrastructural study
16. T cell-dependent activation of macrophages and enhancement of their phagocytic activity in the lungs of mice inoculated with heat-killed Cryptococcus neoformans: Involvement of IFN-γ and its protective effect against cryptococcal infection
17. Activation of macrophages and expansion of specific T lymphocytes in the lungs of mice intratracheally inoculated with Cryptococcus neoformans
18. Expression of cytokines and inducible nitric oxide synthase mRNA in the lung of mice infected with Cryptococcus neoformans: Effects of interleukin-12
19. Contribution of interferon-γ in protecting mice during pulmonary and disseminated infection with Cryptococcus neoformans
20. IL-12 protects mice against pulmonary and disseminated infection caused by Cryptococcus neoformans
21. Requirement for delivery of signals by physical interaction and soluble factors from accessory cells in the induction of receptor-mediated T cell proliferation. Effectiveness of IFN-γ modulation of accessory cells for physical interaction with T cells
22. IgE and eosinophil regulation in a murine model of allergic aspergillosis
23. A murine model of allergic bronchopulmonary aspergillosis with elevated eosinophils and IgE
24. Natural killer cells participate in the early defence against Leishmania major
25. Interleukin-4 transgenic mice of resistant background are susceptible to Leishmania major infection
26. Gamma interferon gene expression and release in human lymphocytes directly activated by Crytococcus neoformans and Candida albicans
27. Effect of degree of encapsulation upon virulence of Cryptococcus neoformans
28. Killing of Cryptococcus neoformans strains by human neutrophils and monocytes
29. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activity and secreted proteins
30. The expanding universe of T-cell subsets: Th1, Th2 and more
31. Nitric oxide as a secretary product of mammalian cells
32. Combined effects of IL-12 and IL-18 on the clinical course and local cytokine production in murine pulmonary infection with Cryptococcus neoformans
33. Complement component C5 is required for release of alveolar macrophage-derived neutrophil chemotactic activity
34. A role for γδ + T cells during experimental infection of mice with Leishmania major
35. A monoclonal antibody to gamma interferon blocks augmentation of natural killer cell activity induced during systemic cryptococcosis
36. Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice
37. Fungal infections in AIDS patients
38. Virulence, capsule size and lipid composition interrelation of Cryptococcus neoformans
39. Encapsulation of Cryptococcus neoformans regulates fungicidal activity and the antigen presentation process in human alveolar macrophage
40. Purified capsular polysaccharide of Cryptococcus neoformans induces interleukin-10 secretion by human monocytes
41. Downregulation by cryptococcal polysaccharide of tumor necrosis factor alpha and interleukin- 1 β secretion from human monocytes
42. Influence of molecular sizes of Cryptococcus neoformans capsular polysaccharide on phagocytosis
43. Role of NK 1.1 + T cells in a Th2 response and in immunoglobulin E production