K-ras mutations in lung carcinomas from nonsmoking women exposed to unvented coal smoke in China

Lung Cancer

Volumn 41, Issue 1, 2003, Pages 21-27

  Keohavong, Phouthone ^a,c   Lan, Qin ^d   Gao, Wei Min ^a   DeMarini, David M ^f   Mass, Marc J ^f   Li, Xue Ming ^e   Roop, Barbara C ^f   Weissfeld, Joel ^b,c   Tian, Defa ^d   Mumford, Judy L ^f  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e Inst of Environ Hlth and Eng   (China)

^f U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Coal combustion; Lung cancer; Nonsmoking women; Ras Oncogene; Sputum

Indexed keywords

COAL;

ADULT; AGED; ARTICLE; CANCER GENETICS; CHINA; CIGARETTE SMOKING; CODON; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MUTATION RATE; ONCOGENE K RAS; POPULATION GENETICS; PRIORITY JOURNAL; SEX DIFFERENCE; SMOKE; SPUTUM ANALYSIS; STATISTICAL ANALYSIS;

EID: 0038121540     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-5002(03)00125-9     Document Type: Article

References (28)

1. Pisani P., Parkin D.M., Bray F.I., Ferlay J. Estimates of the worldwide mortality from 25 major cancers in 1990. Int. J. Cancer. 83:1999;18-29.
2. Mumford J.L., He X.Z., Chapman R.S., et al. Lung cancer and indoor air pollution in Xuan Wei, China. Science. 235:1987;217-220.
3. Loeb L.A., Ernster V.L., Warner K.E., Abbotts J., Laszlo J. Smoking and lung cancer: an overview. Cancer Res. 44:1984;5940-5958.
4. Bos J.L. ras Oncogenes in human cancer: a review. Cancer Res. 49:1989;4682-4689.
5. Suzuki Y., Orita M., Shiraishi M., Hayashi K., Sekiya T. Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products. Oncogene. 5:1990;1037-1043.
6. Rodenhuis S., Slebos R.J.C. Clinical significance of ras oncogene activation in human lung cancer. Cancer Res. 52 (suppl):1992;2665-2669.
7. Sugio K., Ishida T., Yokoyama H., Inoue T., Sigimachi K., Sasazuki T. ras gene mutation as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis. Cancer Res. 52:1992;2903-2906.
8. Westra W.H., Slebos R.J., Offerhaus G.J., et al. K-ras oncogene activation in lung adenocarcinomas from former smokers. Cancer. 72:1993;432-438.
9. Husgafvel-Pursianen K., Kacman P., Ridanpaa M., et al. K-ras mutations in human adenocarcinoma of the lung: association with smoking and occupational exposure to asbestos. Int. J. Cancer. 53:1993;250-256.
10. Keohavong P., DeMichelle M.A.A., Melacrinos A.C., Landreneau R.J., Weyant R.J., Siegfried J.M. Detection of K-ras mutations in lung carcinomas: relationship to prognosis. Clin. Cancer Res. 2:1996;411-418.
11. Siegfried J.M., Gillespie A.T., Mera R., et al. Prognostic value of specific K-ras mutations in lung adenocarcinomas. Cancer Epidemiol. Biomarkers Prev. 6:1997;841-847.
12. Gealy R., Zhang L., Siegfried J.M., Luketich J.D., Keohavong P. Comparison of mutations in the p53 and K-ras genes in lung carcinomas from smoking and nonsmoking women. Cancer Epidemiol. Biomarkers Prev. 8:1999;297-302.
13. Greenblatt M.S., Bennett W.P., Hollstein M., Harris C.C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 54:1994;4855-4878.
14. DeMarini D.M., Landi S., Tian D., et al. Lung tumor K-ras and p53 mutations in nonsmokers reflects exposure to PAH-rich coal combustion emissions. Cancer Res. 61:2001;6679-6681.
15. Lan Q., He X., Costa D.J., et al. Indoor coal combustion emissions, GSTM1 and GSTT1 genotypes, and lung cancer risk: a case-control study in Xuan Wei, China. Cancer Epidemiol. Biomarkers Prev. 9:2000;605-608.
16. World Medical Association Declaration of Helsinki Forty first World Medical Assembly, Hong Kong, 1989.
17. Keohavong P., Zhu D., Whiteside T.L., et al. Detection of infrequent and multiple K-ras mutations in human tumors and tumor-adjacent tissues. Anal. Biochem. 247:1997;394-403.
18. Mazur M., Glickman B.W. Sequence specificity of mutations induced by benzo(a)pyrene-7, 8-diol-9, 10-epoxide at endogenous aprt gene in CHO cells. Somatic Cell. Mol. Genet. 14:1988;393-400.
19. Keohavong P., Thilly W.G. Fidelity of DNA polymerases in DNA amplification. Proc. Natl. Acad. Sci. USA. 86:1989;9253-9257.
20. Zhang LF, Gao WM, Gealy R et al. Comparison of K-ras gene mutations in tumor and sputum DNA of patients with lung cancer. Biomarkers, in press.
21. Mumford J.L., Li X., Hu F., Lu X.B., Chuang J.C. Human exposure and dosimetry of polycyclic aromatic hydrocarbons in urine from Xuan Wei, China with high lung cancer mortality associated with exposure to unvented coal smoke. Carcinogenesis. 16:1995;3031-3036.
22. Mass M.J., Marr C.M., Mumford J.L. Preneoplastic transformation of respiratory epithelial cells by complex organic mixtures in a clonal assay. Gray P.H., Chess E.K., Mellinger P.J., Riley J.R., Spriger D.L. Health and environmental research on complex organic mixtures. 1982;317-327 Pacific Northwest Laboratory, Richland, WA. Conf-851027.
23. Mumford J.L., Chapman R.S., Nesnow S., Helmes C.T., Li X.M. Mutagenicity, carcinogenicity, and human cancer risk from indoor exposure to coal and wood combustion in Xuan Wei, China. Waters M., Daniels F.B., Lewtas J., Moor M.M., Nesnow S. Genetic toxicology of complex mixtures. 39:1990;157-163 Environmental Sciences Research, Plenum Press, New York.
24. Li X.M., Cheng B.S., Wang L.E., et al. Carcinogenicity and fractionation of organic extracts of inhalable particles from indoor smoky coal combustion emission in Xuan Wei, China. J. Chin. Prev. Med. 15:1989;28-34.
25. Mumford J.L., Helmes C.T., Li X.M., Seidenberg J., Nesnow S. Mouse skin tumorigenicity studies of indoor coal and wood combustion emission from homes of residents of Xuan Wei, China, with high lung cancer mortality. Carcinogenesis. 11:1990;397-403.
26. Chuang J.C., Wise S.A., Cao S., Mumford J.L. Chemical characterization of mutagenic fractions of particles from indoor coal combustion: a study of lung cancer in Xuan Wei, China. Environ. Sci. Technol. 26:1992;999-1004.
27. Mumford J.L., Li X.M., Lewtas J., Young T.L., Stella R.M. DNA adducts as a marker for assessing human exposure to polycyclic aromatic hydrocarbons in human tissue from Xuan Wei women with high exposure to coal combustion emission and with high lung cancer mortality. Environ. Health Perspect. 94:1993;9-18.
28. Robertson I.G.C., Santella R.M., Li X.M., et al. DNA adducts in placentas of individuals exposed to high levels of coal combustion emission. Cooke M., Loening K., Merritt J. Polynuclear aromatic hydrocarbons XI: measurements, means, and metabolism, eleventh international symposium on polynuclear aromatic hydrocarbons. 1990;753-765 Batelle Press, Columbus, OH.