Comparison of mutations in the p53 and K-ras genes in lung carcinomas from smoking and nonsmoking women

Cancer Epidemiology Biomarkers and Prevention

Volumn 8, Issue 4 I, 1999, Pages 297-302

  Gealy, Robert ^a   Zhang, Lifang ^a   Siegfried, Jill M ^b,d   Luketich, James D ^c,d   Keohavong, Phouthone ^a,d,e  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^d UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; RAS PROTEIN;

ARTICLE; CLINICAL ARTICLE; DNA DETERMINATION; FEMALE; GENE DELETION; GENE FREQUENCY; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG CARCINOMA; ONCOGENE K RAS; PRIORITY JOURNAL; SMOKING; SURVIVAL TIME;

ADULT; AGED; BASE SEQUENCE; BIOPSY, NEEDLE; CASE-CONTROL STUDIES; COHORT STUDIES; CULTURE TECHNIQUES; DNA, NEOPLASM; FEMALE; GENES, P53; GENES, RAS; GENETIC MARKERS; HUMANS; LUNG NEOPLASMS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; REFERENCE VALUES; SMOKING;

EID: 0032954937     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Boring, C. C., Squires, T. S., and Tong, T. Cancer Statistics. CA Cancer J. Clin., 43: 7-26, 1993.
2. United States Department of Health and Human Services. Strategies to control tobacco use in the United States. Tobacco Control Monogr., 1: 1-307, 1991.
3. United States Surgeon General. Reducing the health consequences of smoking. Twenty-five years of progress. USPHS Pub. No. (CDC) 89-8411. Rockville, MD: Department of Health and Human Services, 1989.
4. Harris, R. E., Zang, E. R., Anderson, J. I., and Wynder, E. L. Race and sex differences in lung cancer risk associated with cigarette smoking. Int. J. Epidemiol., 22: 592-599, 1993.
5. Kabat, G. C. Aspects of the epidemiology of lung cancer in smokers and nonsmokers in the United States. Lung Cancer, 15: 1-20, 1996.
6. Fontham, E. T. H., Correa, P., Wu-Williams, A., Reynolds, P., Greenburg, R. S., Buffler, P. A., Chen, V. W., Boyd, P., Alterman, T., Austin, D. F., Liff, J., and Greenburg, S. D. Lung cancer in nonsmoking women: a multicenter case-control study. Cancer Epidemiol. Biomark. Prev., 1: 35-43, 1991.
7. Mumford, J. L., He, X. Z., Chapman, R. S., Cao, S. R., Harris, D. B., Li, X. M., Xian, Y. L., Jiang, W. Z., Xu, C. W., Chuang, J. C., Wilson, W. E., and Cooke, M. Lung cancer and indoor air pollution in Xuan Wei, China. Science (Washington DC), 235: 217-220, 1987.
8. Taioli, E., and Wynder, E. L. Endocrine factors and adenocarcinoma of the lung in women. J. Natl. Cancer Inst., 86: 869-870, 1994.
9. Ernster, V. L. The epidemiology of lung cancer in women. Ann. Epidemiol., 4: 102-110, 1994.
10. Rodenhuis, S., and Slebos, R. J. C. Clinical significance of ras oncogene activation in human lung cancer. Cancer Res., 52 (Suppl.): 2665s-2669s, 1992.
11. Greenblatt, M. S., Bennett, W. P., Hollstein, M., and Harris, C. C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 54: 4855-4878, 1994.
12. Keohavong, P., DeMichelle, M. A. A., Melacrinos, A. C., Landreneau, R. J., Weyant, R. J., and Siegfried, J. M. Detection of K-ras mutations in lung carcinomas: relationship to prognosis. Clin. Cancer Res., 2: 441-418, 1996.
13. Siegfried, J. M., Gillespie, A. T., Mera, R., Casey, T. J., Keohavong, P., Testa, J. R., and Hunt, J. D. Prognostic value of specific K-ras mutations in lung adenocarcinomas. Cancer Epidemiol. Biomark. Prev., 6: 841-847, 1997.
14. Hernandez-Boussard, T. M., and Hainaut, P. A specific spectrum of p53 mutations in lung cancer from smokers: review of mutations compiled in the IARC p53 database. Environ. Health Perspect., 106: 385-391, 1998.
15. Orita, M., Iwahana, H., Kanazava, H., Hayashi, K., and Sekiya, T. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformational polymorphisms. Proc. Natl. Acad. Sci. USA, 86: 2766-2770, 1989.
16. Hainaut, P., Hernandez, T., Robinson, A., Rodriguez-Tome, P., Flores, T., Hollstein, M. Harris, C. C., and Montesano, R. IARC database of p53 mutations in human tumors and cell lines: updated compilation, revised formats and new visualization tool. Nucleic Acids Res., 26: 205-213, 1998.
17. Smida, J., Zitzelsberger, H., Kellerer, A. M., Lehmann, L., Minkus, G., Negele, T., Spelberg, F., Hieber, L., Demidchik, E. P., Longfelder, E., and Bauchinger, M. p53 mutations in childhood thyroid tumors from Belarus and in thyroid tumors without radiation history. Int. J. Cancer, 73: 802-807, 1997.
18. Husgafvel-Pursiainen, K., Ridanpaa, M., Anttila, S., and Vainio, H. p53 and ras gene mutations in lung cancer: implications for smoking and occupational exposure. J. Occup. Environ. Med., 37: 69-76, 1995.
19. Kure, E. H., Ryberg, D., Hewer, A., Phillips, D. H., Skaug, V., Baera, R., and Haugen, A. p53 mutations in lung tumors: relationship to gender and lung DNA adducts levels. Carcinogenesis (Lond.), 17: 2201-2205, 1996.
20. Husgafvel-Pursiainen, K., and Kannio, A. Cigarette smoking and p53 mutations in lung cancer and bladder cancer. Environ. Health Perspect., 104 (Suppl. 3): 553-556, 1996.
21. Takeshima, Y., Seyama, T., Bennett, W. P., Akiyama, M., Tokuoka, S., Inai, K., Mabuchi, K., Land, C. E., and Harris, C. C. p53 mutations in lung cancers from non-smoking atomic bomb survivors. Lancet, 342: 1520-1521, 1993.
22. Rideout, W. M., Coetzee, G. A., Olumi, A. F., and Jones, P. A. 5-methylcytosine as an endogenous mutagen in the human LDL receptor and p53 gene. Science (Washington DC), 249: 1288-1290, 1990.
23. Keohavong, P., and Thilly, W. G. Fidelity of DNA polymerases in DNA amplification. Proc. Natl. Acad. Sci. USA, 86: 9253-9257, 1989.
24. Bartsch, H., Ohshima, H., Shuker, D. E. G., Pignatelli, B., and Calmels, S. Exposure of humans to endogenous N-nitoso compounds: implications in cancer etiology. Mutat. Res., 238: 255-267, 1990.