Adiponectin/Acrp30, and adipocyte-specific secretory factor: Physiological relevance during development

Pediatric Diabetes

Volumn 4, Issue 1, 2003, Pages 32-37

  Iyengar, Puneeth ^a   Scherer, Philipp E ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Adipokine; Diabetes; Hepatic glucose output; Insulin; Sensitivity

Indexed keywords

4 THIAZOLIDINONE DERIVATIVE; ADIPONECTIN; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUCLADESINE; DEXAMETHASONE; GLUCOCORTICOID; INSULIN; IONOMYCIN; LEPTIN; POLYPEPTIDE; RETINOIC ACID; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ADIPOSE TISSUE; CELL SPECIFICITY; COMPLEX FORMATION; DIABETES MELLITUS; DIABETOGENESIS; DRUG EFFECT; ENDOCRINE GLAND; ENERGY BALANCE; ENERGY METABOLISM; GENE MUTATION; GENETIC SUSCEPTIBILITY; HUMAN; HYPERLIPIDEMIA; INSULIN SENSITIVITY; LIPID STORAGE; LIVER; MUSCLE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PROCESSING; REGULATORY MECHANISM; REVIEW; RISK FACTOR;

ADIPONECTIN; ADIPOSE TISSUE; ADULT; AGED; ANIMALS; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 2; ENERGY METABOLISM; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INDIANS, NORTH AMERICAN; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; MUTATION; PROTEINS;

EID: 0038105956     PISSN: 1399543X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-5448.2003.00029.x     Document Type: Review

References (45)

1. ZHANG Y, PROENCA R, MAFFEI M, BARONE M, LEOPOLIO L, FREIDMAN JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994: 372: 425-432.
2. SCHERER PE, WILLIAMS S, FOGLIANO M, BALDINI G, LODISH HF. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 1995: 270: 26 746-26 749.
3. HU E, LIANG P, SPIEGELMAN BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 1996: 271: 10697-10703.
4. MAEDA K, OKUBO K, SHIMOMURA I et al. cDNA cloning and expression of a novel adipose specific collagen-like factor,apM1 (AdiPoseMostabundantGenetranscript 1). Biochem Biophys Res Commun 1996: 221: 286-289.
5. NAKANO Y, TOBE T, CHOI-MIURA NH, MAZDA T, TOMITA M. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem (Tokyo) 1996: 120: 803-812.
6. BERG AH, COMBS TP, SCHERER PE. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 2002: 13: 84-89.
7. FRUEBIS J, TSAO TS, JAVORSCHI S et al. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 2001: 98: 2005-2010.
8. OUCHI N, KIHARA S, ARITA Y et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 2001: 103: 1057-1063.
9. BERG AH, DU COMBS TX, BROWNLEE M, SCHERER PE. The adipocyte-secreted protein acrp30 enhances hepatic insulin action. Nat Med 2001: 7: 947-953.
10. KUBOTA N, TERAUCHI Y, YAMAUCHI T et al. Disruption of adiponectin causes insulin resistance and neointimal formation. J Biol Chem 2002: 277: 25 863-25 866.
11. ARITA Y, KIHARA S, OUCHI N et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999: 257: 79-83.
12. ROSENBAUM M, NICOLSON M, HIRSCH J et al. Effects of gender, body composition, and menopause on plasma concentrations of leptin. J Clin Endocrinol Metab 1996: 81: 3424-3427.
13. YAMAMOTO Y, HIROSE H, SAITO I et al. Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum high-density lipoprotein-cholesterol, independent of body mass index, in the Japanese population. Clin Sci (Lond) 2002: 103: 137-142.
14. HOTTA K, FUNAHASHI T, ARITA Y et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000: 20: 1595-1599.
15. LINDSAY RS, FUNAHASHI T, HANSON RL et al. Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet 2002: 360: 57-58.
16. HOTTA K, FUNAHASHI T, BODKIN NL et al. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 2001: 50: 1126-1133.
17. VASSEUR F, HELBECQUE N, DINA C et al. Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians. Hum Mol Genet 2002: 11: 2607-2614.
18. KONDO H, SHIMOMURA I, MATSUKAWA Y et al. Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome. Diabetes 2002: 51: 2325-2328.
19. TAKAHASHI M, ARITA Y, YAMAGATA K et al. Genomic structure and mutations in adipose-specific gene, adiponectin. Int J Obes Relat Metab Disord 2000:24:861-868.
20. MENZAGHI C, ERCOLINO T, DI PAOLA R et al. A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. Diabetes 2002: 51: 2306-2312.
21. HARA K, BOUTIN P, MORI Y et al. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes 2002: 51: 536-540.
22. STUMVOLL M, TSCHRITTER O, FRITSCHE A et al. Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes. Diabetes 2002: 51: 37-41.
23. COMUZZIE AG, FUNAHASHI T, SONNENBERG G et al. The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome. J Clin Endocrinol Metab 2001: 86: 4321-4325.
24. YAMAMOTO Y, HIROSE H, MIYASHITA K et al. PPAR(gamma)2 gene Pro12Ala polymorphism may influence serum level of an adipocyte-derived protein, adiponectin, in the Japanese population. Metabolism 2002: 51: 1407-1409.
25. COMBS TP, WAGNER JA, BERGER J et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. Endocrinology 2002: 143: 998-1007.
26. IMAGAWA A, FUNAHASHI T, NAKAMURA T et al. Elevated serum concentration of adipose-derived factor, adiponectin, in patients with type 1 diabetes. Diabetes Care 2002: 25: 1665-1666.
27. MATSUBARA M, MARUOKA S, KATAYOSE S. Decreased plasma adiponectin concentrations in women with dyslipidemia. J Clin Endocrinol Metab 2002: 87: 2764-2769.
28. KAZUMI T, KAWAGUCHI A, SAKAI K, HIRANO T, YOSHINO G. Young men with high-normal blood pressure have lower serum adiponectin, smaller LDL size, and higher elevated heart rate than those with optimal blood pressure. Diabetes Care 2002: 25: 971-976.
29. HAQUE WA, SHIMOMURA I, MATSUZAWA Y, GARG A. Serum adiponectin and leptin levels in patients with lipodystrophies. J Clin Endocrinol Metab 2002: 87: 2395.
30. WANG Y, XU A, KNIGHT C, XU LY, COOPER GJ. Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity. J Biol Chem 2002: 277: 19 521-19 529.
31. PAJVANI UB, DU X, COMBS TP et al. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity. J Biol Chem 2002 Dec.20 [epub ahead of print].
32. ZHANG Y, MATHENY M, ZOLOTUKHIN S, TUMER N, SCARPACE PJ. Regulation of adiponectin and leptin gene expression in white and brown adipose tissues: influence of beta3-adrenergic agonists, retinoic acid, leptin and fasting. Biochim Biophys Acta 2002: 1584: 115.
33. DELPORTE ML, FUNAHASHI T, TAKAHASHI M, MATSUZAWA Y, BRICHARD SM. Pre- and post-translational negative effect of beta-adrenoceptor agonists on adiponectin secretion: in vitro and in vivo studies. Biochem J 2002: 367: 677-685.
34. FASSHAUER M, KLEIN J, NEUMANN S, ESZLINGER M, PASCHKE R. Adiponectin gene expression is inhibited by beta-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes. FEBS Lett 2001: 507: 142-146.
35. KAPPES A, LOFFLER G. Influences of ionomycin, dibutyryl-cycloAMP and tumour necrosis factor-alpha on intracellular amount and secretion of apM1 in differentiating primary human preadipocytes. Horm Metab Res 2000: 32: 548-554.
36. MAEDA N, TAKAHASHI M, FUNAHASHI T et al. PPAR-gamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 2001: 50: 2094-2099.
37. MOORE GB, CHAPMAN H, HOLDER JC et al. Differential regulation of adipocytokine mRNAs by rosiglitazone in db/db mice. Biochem Biophys Res Commun 2001: 286: 735-741.
38. YANG WS, JENG CY, WU TJ et al. Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients. Diabetes Care 2002: 25: 376-380.
39. YU JG, JAVORSCHI S, HEVENER AL et al. The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 2002: 51: 2968-2974.
40. HIROSE H, KAWAI T, YAMAMOTO Y et al. Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes. Metabolism 2002: 51: 314-317.
41. FASSHAUER M, KLEIN J, NEUMANN S, ESZLINGER M, PASCHKE R. Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. Biochem Biophys Res Commun 2002: 290: 1084-1089.
42. YANG WS, LEE WJ, FUNAHASHI T et al. Weight reduction increases plasma levels of an adipose-derived antiinflammatory protein, adiponectin. J Clin Endocrinol Metab 2001: 86: 3815-3819.
43. COMBS TP, BERG AH, RAJALA MW et al. Sexual differentiation, pregnancy, calorie restriction and aging affect the adipocyte-specific secretory protein Acrp30/adiponectin. Diabetes 2003: 52: 268-276.
44. MORAN A, JACOBS DR Jr, STEINBERGER J et al. Insulin resistance during puberty: results from clamp studies in 357 children. Diabetes 1999: 48: 2039-2044.
45. STEFAN N, BUNT JC, SALBE AD et al. Plasma adiponectin concentrations in children: relationships with obesity and insulinemia. J Clin Endocrinol Metab 2002: 87: 4652-4656.