In vitro characterization of [3H]MethoxyPyEP, an mGluR5 selective radioligand

Life Sciences

Volumn 73, Issue 3, 2003, Pages 371-379

  Patel, Shil ^a   Krause, Stephen M ^a   Hamill, Terence ^a   Chaudhary, Ashok ^a   Burns, Donald H ^a   Gibson, Raymond A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 3 METHOXY 5 (PYRIDIN 2 YLETHYNYL)PYRIDINE H 3; 4 CARBOXYPHENYLGLYCINE; ATROPINE; AZETIDINE 2,4 DICARBOXYLIC ACID; BENOXANTHIAN; CARBOXYLIC ACID DERIVATIVE; CHEMICAL COMPOUND; CLOZAPINE; DITHIOTHREITOL; DIZOCILPINE; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR ANTAGONIST; KETANSERIN; RADIOLIGAND; TRAXOPRODIL; UNCLASSIFIED DRUG; YOHIMBINE; 3 (3H)METHOXY 5 (PYRIDIN 2 YLETHYNYL)PYRIDINE; 3-(3H)METHOXY-5-(PYRIDIN-2-YLETHYNYL)PYRIDINE; 6 METHYL 2 (PHENYLETHYNYL)PYRIDINE; 6-METHYL-2-(PHENYLETHYNYL)PYRIDINE; LIGAND; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 5; PYRIDINE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BRAIN CORTEX; BRAIN REGION; CEREBELLUM; CONCENTRATION (PARAMETERS); DENSITY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; HIPPOCAMPUS; IN VITRO STUDY; LIGAND BINDING; MALE; NONHUMAN; PH; RAT; ROOM TEMPERATURE; THALAMUS; TIME; TISSUE HOMOGENATE; ANIMAL; BINDING SITE; BRAIN; DRUG ANTAGONISM; METABOLISM; RADIOASSAY; SPRAGUE DAWLEY RAT;

ANIMALS; AUTORADIOGRAPHY; BINDING SITES; BRAIN; CEREBELLUM; HIPPOCAMPUS; HYDROGEN-ION CONCENTRATION; LIGANDS; MALE; PYRIDINES; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; THALAMUS;

EID: 0038075398     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(03)00272-8     Document Type: Article

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