Application of the cytosensor™ microphysiometer to drug discovery

Receptors and Channels

Volumn 9, Issue 2, 2003, Pages 125-131

  Wille, Kirsten ^a   Paige, Lisa A ^b   Higgins, Alan J ^a  

^a Nobex Corporation   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytosensor microphysiometer; Drug discovery; Extracellular PH; Metabolic rate

Indexed keywords

(3 IODOBENZYL)GUANIDINE; ANTIINFLAMMATORY AGENT; CARIPORIDE; CELL SURFACE RECEPTOR; CHEMOKINE RECEPTOR CCR1 ANTAGONIST; CT 025; DELTA OPIATE RECEPTOR AGONIST; EMD 84021; EMD 94309; ENIPORIDE; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; ESCULETIN; GONADORELIN DERIVATIVE; GUANIDINE DERIVATIVE; MONOCLONAL ANTIBODY; N [6 (4 CHLOROPHENOXY)HEXYL] N' CYANO N'' (4 PYRIDYL)GUANIDINE; N,N DIALLYLTYROSYL 2 METHYLALANYL 2 METHYLALANYLPHENYLALANYLLEUCINE; ORAL ANTIDIABETIC AGENT; OROSOMUCOID; PIPERIDINE DERIVATIVE; PROTEIN INHIBITOR; SALCATONIN; SODIUM PROTON EXCHANGE PROTEIN INHIBITOR; SYNTHETIC PEPTIDE; UMBELLIFERONE; UNCLASSIFIED DRUG;

ACIDIFICATION; AREA UNDER THE CURVE; ARTICLE; CANCER IMMUNOTHERAPY; CELL METABOLISM; CLINICAL TRIAL; CORRELATION ANALYSIS; DEVICE; DOSE RESPONSE; DRUG MECHANISM; DRUG RESEARCH; DRUG SCREENING; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LIGAND BINDING; MEDICAL TECHNOLOGY; MICROPHYSIOMETER; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; STRUCTURE ACTIVITY RELATION; BIOCHEMISTRY; INSTRUMENTATION; PH; PHARMACOLOGY;

BIOCHEMISTRY; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGEN-ION CONCENTRATION; PHARMACOLOGY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0038067836     PISSN: 10606823     EISSN: None     Source Type: Journal    
DOI: 10.1080/10606820308246     Document Type: Article

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