Identification and characterization of a novel high affinity metal- binding site in the hammerhead ribozyme

RNA

Volumn 5, Issue 8, 1999, Pages 1099-1104

  Hansen, Mark R ^a   Simorre, Jean Pierre ^a,c   Hanson, Paul ^a   Mokler, Victor ^b   Bellon, Laurent ^b   Beigelman, Leonid ^b   Pardi, Arthur ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b Sirna Therapeutics Inc   (United States)

^c CEA GRENOBLE   (France)

Author keywords

31P NMR; Hammerhead ribozyme; Metal binding

Indexed keywords

MAGNESIUM ION; PHOSPHATE; RIBOZYME; RNA;

ARTICLE; BASE PAIRING; BINDING AFFINITY; BINDING SITE; DISSOCIATION CONSTANT; METAL BINDING; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; X RAY CRYSTALLOGRAPHY;

BASE SEQUENCE; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; IONS; MAGNESIUM; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, GENETIC; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHATES; RNA, CATALYTIC;

EID: 0032821319     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838299990738     Document Type: Article

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