Use of oral sildenafil (Viagra®) in pulmonary hypertension after cardiac pediatric surgery;Intérêt du sildénafil (Viagra®) per os en cas d'hypertension artérielle pulmonaire après chirurgie cardiaque pédiatrique

Annales Francaises d'Anesthesie et de Reanimation

Volumn 22, Issue 2, 2003, Pages 140-143

  Laquay, N ^a   Levy M L ^a   Vaccaroni, L ^a   Mauriat, Ph ^a   Carli, P ^a  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

Cardiac pediatric surgery; Phosphodiesterase inhibition; Pulmonary hypertension; Sildenafil (Viagra )

Indexed keywords

CAPTOPRIL; MILRINONE; NITRIC OXIDE; SILDENAFIL;

ARTICLE; CASE REPORT; CLINICAL EXAMINATION; FEMALE; HEART ATRIUM SEPTUM DEFECT; HEART SURGERY; HUMAN; LENGTH OF STAY; MITRAL VALVE REGURGITATION; MORBIDITY; PEDIATRIC SURGERY; POSTOPERATIVE COMPLICATION; PULMONARY HYPERTENSION; SCHOOL CHILD;

EID: 0038031920     PISSN: 07507658     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0750-7658(02)00863-8     Document Type: Article

References (20)

1. Joumois D, Pouard P, Mauriat P, Malhere T, Vouhé P, Safran D. Inhaled nitric oxide as a therapy for pulmonary hypertension after operations for congenital heart defect. J Thorac Cardiovasc Surg 1994;107:1129-35.
2. Pepke-Zaba J, Higgenbottam TW, Dinh-Xuan AT, Stone D, Wallwork J. Inhaled nitric oxide as a cause of a selective pulmonary vasodilation in pulmonary hypertension. Lancet 1991;338:1173-4.
3. Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA. Oral Sildenafil in the treatment of erectile dysfunction. N Engl J Med 1998;338:1397-404.
4. Atz AM, Wessel DL. Sildenafil ameliorates effects of inhaled nitric oxide withdrawal. Anesthesiology 1999;91:308-12.
5. Rubin LJ. Primary Pulmonary Hypertension. N Engl J Med 1997;336:111-7.
6. Barst RJ, Rubin LJ, Long WA, Mc Goon MD, Rich S, Badesch BD, et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. N Engl J Med 1996;334:296-302.
7. Barst RJ, Maislin G, Fishman AP. Vasodilator therapy for primary pulmonary hypertension in children. Circulation 1999;99:1197-208.
8. Ghofrani HA, Wiedemann R, Rose F, Olschewski H, Schermuly RT, Weissmann N, et al. Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension. Ann Intern Med 2002;136:515-22.
9. Sanchez LS, de la Monte SM, Filippov G, Jones RC, Zapol WM, Bloch KD. Cyclic-GMP-binding, Cyclic-GMP-specific phosphodiesterase (PDE 5) gene expression is regulated during rat pulmonary development. Pediatr Res 1998;43:163-8.
10. Goldman AP, Haworth SG, Macrae DJ. Does inhaled nitric oxide suppress endogenous nitrous oxide production? J Thorac Cardiovasc Surg 1996;112:541-2.
11. Wedgwood S, McMullan DM, Bekker JM, Finemann JR, Black SM. Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy. Circ Res 2001;89:357-64.
12. Weimann J, Ullrich R, Hromi J, Fujino Y, Clark MWH, Bloch KD, et al. Sildenafil is a pulmonary vasodilator in awake lambs with acute pulmonary hypertension. Anesthesiology 2000;92:1702-12.
13. Lodato R. Viagra for impotence of pulmonary vasodilator therapy? Am J Respir Crit Care Med 2001;163:312-3.
14. Stief CG, Uckert S, Becker AJ, Harringer W, Truss MC, Forssmann WG, et al. Effects of sildenafil on cAMP and cGMP levels in isolated human cavernous and cardiac tissue. Urology 2000;55:146-50.
15. Ishikura F, Beppu S, Hamada T, Khandheria K, Seward JB, Nehra A. Effects of sildenafil citrate (Viagra®) combined with nitrate on the heart. Circulation 2000;102:2516-23.
16. Abrams D, Schulze-Neick I, Magee AG. Sildenafil as a selective pulmonary vasodilator in childhood primary pulmonary hypertension. Heart 2000;84:E4.
17. Bigatello LM, Hess D, Dennehy KC, Medoff BD, Hurford WE. Sildenafil can increase the response to inhaled nitric oxide. Anesthesiology 2000;92:1827-9.
18. Prasad S, Wilkinson J, Gatzoulis MA. Sildenafil in primary pulmonary hypertension [letter]. N Engl J Med 2000;343:1342.
19. Shekerdemian LS, Ravn HB, Penny DJ. Intravenous sildenafil lowers pulmonary vascular resistance in a model of neonatal pulmonary hypertension. Am J Respir Crit Care Med 2002;165:1098-102.
20. Schmidt HH, Lohmann SM, Walter U. The nitric oxide and cGMP signal transduction system: regulation and mechanism of action. Biochim Biophys Acta 1993;1178:153-75.