메뉴 건너뛰기




Volumn 88, Issue 7, 2003, Pages 1017-1024

Neoadjuvant systemic fluorouracil and mitomycin C prior to synchronous chemoradiation is an effective strategy in locally advanced rectal cancer

Author keywords

Circumferential resection margin; Fluorouracil; Magnetic resonance imaging; Neoadjuvant chemotherapy; Radiotherapy

Indexed keywords

FLUOROURACIL; MITOMYCIN C;

EID: 0038030757     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600822     Document Type: Article
Times cited : (67)

References (50)
  • 1
    • 0038339773 scopus 로고    scopus 로고
    • National Cancer Institute Bethesda
    • National Cancer Institute-Common Toxicity Criteria (1998) National Cancer Institute Bethesda http://ctep.cancer.gov/reporting/ctc.html
    • (1998)
  • 9
    • 0034706001 scopus 로고    scopus 로고
    • Preoperative radiotherapy for resectable rectal cancer: A meta-analysis
    • Camma C, Giunta M, Fiorica F, Pagliaro L, Craxi A, Cottone M (2000) Preoperative radiotherapy for resectable rectal cancer: a meta-analysis. JAMA 284: 1008-1015
    • (2000) JAMA , vol.284 , pp. 1008-1015
    • Camma, C.1    Giunta, M.2    Fiorica, F.3    Pagliaro, L.4    Craxi, A.5    Cottone, M.6
  • 10
    • 0034307087 scopus 로고    scopus 로고
    • Preoperative chemotherapy and pelvic radiation for tethered or fixed rectal cancer: A phase II close escalation study
    • Chan AK, Wong AO, Langevin J, Jenken D, Heine J, Buie D, Johnson DR (2000) Preoperative chemotherapy and pelvic radiation for tethered or fixed rectal cancer: a phase II close escalation study. Int J Radiat Oncol Biol Phys 48: 843-856
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 843-856
    • Chan, A.K.1    Wong, A.O.2    Langevin, J.3    Jenken, D.4    Heine, J.5    Buie, D.6    Johnson, D.R.7
  • 11
    • 0035922657 scopus 로고    scopus 로고
    • Adjuvant radiotherapy for rectal cancer: A systematic overview of 8,507 patients from 22 randomised trials
    • Colorectal Cancer Collaborative Group (2001) Adjuvant radiotherapy for rectal cancer: a systematic overview of 8,507 patients from 22 randomised trials. Lancet 358: 1291-1304
    • (2001) Lancet , vol.358 , pp. 1291-1304
  • 13
    • 0033504317 scopus 로고    scopus 로고
    • Improved survival and reduction in local failure rates after preoperative radiotherapy: Evidence for the generalizability of the results of Swedish Rectal Cancer Trial
    • Dahlberg M, Glimelius B, Pahlman L (1999) Improved survival and reduction in local failure rates after preoperative radiotherapy: evidence for the generalizability of the results of Swedish Rectal Cancer Trial. Ann Surg 229: 493-497
    • (1999) Ann Surg , vol.229 , pp. 493-497
    • Dahlberg, M.1    Glimelius, B.2    Pahlman, L.3
  • 15
    • 0036787579 scopus 로고    scopus 로고
    • Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer
    • Dunst J, Reese T, Sutter T, Zuhlke H, Hinke A, Kolling-Schlebusch K, Frings S (2002) Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer. J Clin Oncol 20: 3983-3991
    • (2002) J Clin Oncol , vol.20 , pp. 3983-3991
    • Dunst, J.1    Reese, T.2    Sutter, T.3    Zuhlke, H.4    Hinke, A.5    Kolling-Schlebusch, K.6    Frings, S.7
  • 16
    • 0035340318 scopus 로고    scopus 로고
    • Addition of oxaliplatin to continuous fuorouracil, 1-folinic acid, and concomitant radiotherapy in rectal cancer: The Lyon R 97-03 phase I trial
    • Freyer G, Bossard N, Romestaing P, Mornex F, Chapet O, Trillet-Lenoir V, Gerard JP (2001) Addition of oxaliplatin to continuous fuorouracil, 1-folinic acid, and concomitant radiotherapy in rectal cancer: the Lyon R 97-03 phase I trial. J Clin Oncol 19: 2433-2438
    • (2001) J Clin Oncol , vol.19 , pp. 2433-2438
    • Freyer, G.1    Bossard, N.2    Romestaing, P.3    Mornex, F.4    Chapet, O.5    Trillet-Lenoir, V.6    Gerard, J.P.7
  • 17
    • 4243326628 scopus 로고    scopus 로고
    • Oxaliplatin, fuorouracil, I-leucovorin and radiotherapy (FolfoR 2) as preoperative treatment of advanced rectal cancer: The Lyon R0-04 phase II trial
    • Gerard JP, Chapet O, Romestaing P, Mornex F, Coquard R, Barber N, Atlan D, Freyer G (2002) Oxaliplatin, fuorouracil, I-leucovorin and radiotherapy (FolfoR 2) as preoperative treatment of advanced rectal cancer: the Lyon R0-04 phase II trial. Proc Am Soc Clin Oncol 21: 146a
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Gerard, J.P.1    Chapet, O.2    Romestaing, P.3    Mornex, F.4    Coquard, R.5    Barber, N.6    Atlan, D.7    Freyer, G.8
  • 19
    • 0034824222 scopus 로고    scopus 로고
    • Chemoradiotherapy for rectal cancer-is there an optimal combination?
    • Glimelius B (2001) Chemoradiotherapy for rectal cancer-is there an optimal combination? Ann Oncol 12: 1039-1045
    • (2001) Ann Oncol , vol.12 , pp. 1039-1045
    • Glimelius, B.1
  • 20
    • 0001430825 scopus 로고    scopus 로고
    • N9741: Oxaliplatin (oxal) or CPT-11+5-fluorouracil (5FU)/leucovorin (LV) or oxal+CPT-11 in advanced colorectal cancer. Initial toxicity and response data from a GI Intergroup study
    • Goldberg RM, Morton RF, Sargent DJ, Fuchs C, Ramanthan RK, Williamson SK, Findlay, BP (2002) N9741: oxaliplatin (oxal) or CPT-11+5-fluorouracil (5FU)/leucovorin (LV) or oxal+CPT-11 in advanced colorectal cancer. Initial toxicity and response data from a GI Intergroup study. Proc Am Soc Clin Oncol 21: 128a
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Goldberg, R.M.1    Morton, R.F.2    Sargent, D.J.3    Fuchs, C.4    Ramanthan, R.K.5    Williamson, S.K.6    Findlay, B.P.7
  • 22
    • 0033180254 scopus 로고    scopus 로고
    • Improved survival and local control after total mesorectal excision or D3 lymphadenectomy in the treatment of primary rectal cancer: An international analysis of 1411 patients
    • Havenga K, Enker WE, Norstein J, Moriya Y, Heald RJ, van Houwelingen HC, Van de Velde CJ (1999) Improved survival and local control after total mesorectal excision or D3 lymphadenectomy in the treatment of primary rectal cancer: an international analysis of 1411 patients. Eur J Surg Oncol 25: 368-374
    • (1999) Eur J Surg Oncol , vol.25 , pp. 368-374
    • Havenga, K.1    Enker, W.E.2    Norstein, J.3    Moriya, Y.4    Heald, R.J.5    Van Houwelingen, H.C.6    Van De Velde, C.J.7
  • 23
    • 0031859317 scopus 로고    scopus 로고
    • Rectal cancer: The Basingstoke experience of total mesorectal excision, 1978-1997
    • Heald RJ, Moran BJ, Ryall RD, Sexton R, MacFarlane JK (1998) Rectal cancer: the Basingstoke experience of total mesorectal excision, 1978-1997. Arch Surg 133: 894-899
    • (1998) Arch Surg , vol.133 , pp. 894-899
    • Heald, R.J.1    Moran, B.J.2    Ryall, R.D.3    Sexton, R.4    MacFarlane, J.K.5
  • 27
    • 18544366219 scopus 로고    scopus 로고
    • Impact of the introduction and training of total mesorectal excision on recurrence and survival in rectal cancer in The Netherlands
    • Kapiteijn E, Putter H, Van de Velde CJ (2002) Impact of the introduction and training of total mesorectal excision on recurrence and survival in rectal cancer in The Netherlands. Br J Surg 89: 1142-1149
    • (2002) Br J Surg , vol.89 , pp. 1142-1149
    • Kapiteijn, E.1    Putter, H.2    Van De Velde, C.J.3
  • 28
    • 33845382806 scopus 로고
    • Non parametric estimation from incomplete observations
    • Kaplan EL, Meier P (1958) Non parametric estimation from incomplete observations. J Am Statist Assoc 53: 457-481
    • (1958) J Am Statist Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 29
    • 0036804343 scopus 로고    scopus 로고
    • Preoperative chemoradiation using oral capecitablne in locally advanced rectal cancer
    • Kim JS, Kim JS, Cho MJ, Song KS, Yoon WH (2002) Preoperative chemoradiation using oral capecitablne in locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 54: 403-408
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 403-408
    • Kim, J.S.1    Kim, J.S.2    Cho, M.J.3    Song, K.S.4    Yoon, W.H.5
  • 30
    • 0037099604 scopus 로고    scopus 로고
    • Multicenter randomized phase III trial comparing protracted venous infusion (PVI) fluorouracil (5-FU) with PVI 5-FU plus mitomycin in inoperable pancreatic cancer
    • Maisey N, Chau I, Cunningham D, Norman A, Seymour M, Hickish T, Iveson T, O'Brien M, Tebbutt N, Harrington A, Hill M (2002) Multicenter randomized phase III trial comparing protracted venous infusion (PVI) fluorouracil (5-FU) with PVI 5-FU plus mitomycin in inoperable pancreatic cancer. J Clin Oncol 20: 3130-3136
    • (2002) J Clin Oncol , vol.20 , pp. 3130-3136
    • Maisey, N.1    Chau, I.2    Cunningham, D.3    Norman, A.4    Seymour, M.5    Hickish, T.6    Iveson, T.7    O'Brien, M.8    Tebbutt, N.9    Harrington, A.10    Hill, M.11
  • 32
    • 0036190416 scopus 로고    scopus 로고
    • Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: Not one millimeter but two millimeters is the limit
    • Nagtegaal ID, Marijnen CA, Kranenbarg EK, Van de Velde CJ, van Krieken JH (2002) Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: not one millimeter but two millimeters is the limit. Am J Surg Pathol 26: 350-357
    • (2002) Am J Surg Pathol , vol.26 , pp. 350-357
    • Nagtegaal, I.D.1    Marijnen, C.A.2    Kranenbarg, E.K.3    Van De Velde, C.J.4    Van Krieken, J.H.5
  • 35
    • 0022466378 scopus 로고
    • Local recurrence of rectal adenocarcinoma due to inadequate surgical resection. Histopathological study of lateral tumour spread and surgical excision
    • Quirke P, Durdey P, Dixon MF, Williams NS (1986) Local recurrence of rectal adenocarcinoma due to inadequate surgical resection. Histopathological study of lateral tumour spread and surgical excision. Lancet 2: 996-999
    • (1986) Lancet , vol.2 , pp. 996-999
    • Quirke, P.1    Durdey, P.2    Dixon, M.F.3    Williams, N.S.4
  • 37
    • 0001688836 scopus 로고    scopus 로고
    • Phase III randomized trial of preoperative versus postoperative multimodality therapy in patients with carcinoma of the rectum (NSABP R-03)
    • Roh M, Petrelli N, Wieand S, Colangelo L, Smith R, Mamounas E, Hyams D, Wolmark N (2001) Phase III randomized trial of preoperative versus postoperative multimodality therapy in patients with carcinoma of the rectum (NSABP R-03). Proc Am Soc Clin Oncol 20: 123a
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Roh, M.1    Petrelli, N.2    Wieand, S.3    Colangelo, L.4    Smith, R.5    Mamounas, E.6    Hyams, D.7    Wolmark, N.8
  • 38
    • 0037090686 scopus 로고    scopus 로고
    • Prospective randomized trial comparing mitomycin, cisplatin, and protracted venous-infusion fluorouracil (PVI 5-FU) with epirubicin, cisplatin, and PVI 5-FU in advanced esophagogastric cancer
    • Ross P, Nicolson M, Cunningham D, Valle J, Seymour M, Harper P, Price T, Anderson H, Iveson T, Hickish T, Lofts F, Norman A (2002) Prospective randomized trial comparing mitomycin, cisplatin, and protracted venous-infusion fluorouracil (PVI 5-FU) with epirubicin, cisplatin, and PVI 5-FU in advanced esophagogastric cancer. J Clin Oncol 20: 1996-2004
    • (2002) J Clin Oncol , vol.20 , pp. 1996-2004
    • Ross, P.1    Nicolson, M.2    Cunningham, D.3    Valle, J.4    Seymour, M.5    Harper, P.6    Price, T.7    Anderson, H.8    Iveson, T.9    Hickish, T.10    Lofts, F.11    Norman, A.12
  • 40
    • 0024521170 scopus 로고
    • Time-dependent interactions between 5-fluorouracil and mitomycin C on a human colon carcinoma cell line, HCT-8, in vitro
    • Russello O, Romanini A, Civalleri D, Rosso R, Nicolin A, Sobrero A (1989) Time-dependent interactions between 5-fluorouracil and mitomycin C on a human colon carcinoma cell line, HCT-8, in vitro. Eur J Cancer Clin Oncol 25: 571-572
    • (1989) Eur J Cancer Clin Oncol , vol.25 , pp. 571-572
    • Russello, O.1    Romanini, A.2    Civalleri, D.3    Rosso, R.4    Nicolin, A.5    Sobrero, A.6
  • 42
    • 0042955146 scopus 로고    scopus 로고
    • Preoperative radiation and oxaliplatin in combination with 5-fluorouracil and low-dose leucovorin in locally advanced rectal cancer
    • Sebag-Montefiore D, Glynn RJ, Falk S, Maughan T, Meadows HM (2002) Preoperative radiation and oxaliplatin in combination with 5-fluorouracil and low-dose leucovorin in locally advanced rectal cancer. Proc Am Soc Clin Oncol 21: 146a
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Sebag-Montefiore, D.1    Glynn, R.J.2    Falk, S.3    Maughan, T.4    Meadows, H.M.5
  • 43
    • 1842377447 scopus 로고    scopus 로고
    • Improved survival with preoperative radiotherapy in resectable rectal cancer
    • Swedish Rectal Cancer Trial (1997) Improved survival with preoperative radiotherapy in resectable rectal cancer. N Engl J Med 336: 980-987
    • (1997) N Engl J Med , vol.336 , pp. 980-987
  • 45
    • 0036771724 scopus 로고    scopus 로고
    • A multicentre, randomised phase III trial comparing protracted venous infusion (PVI) 5-fluorouracil (5-FU) with PVI 5-FU plus mitomycin C in patients with inoperable oesophago-gastric cancer
    • Tebbutt NC, Norman A, Cunningham D, Iveson T, Seymour M, Hickish T, Harper P, Maisey N, Mochlinski K, Prior Y, Hill M (2002) A multicentre, randomised phase III trial comparing protracted venous infusion (PVI) 5-fluorouracil (5-FU) with PVI 5-FU plus mitomycin C in patients with inoperable oesophago-gastric cancer. Ann Oncol 13: 1568-1575
    • (2002) Ann Oncol , vol.13 , pp. 1568-1575
    • Tebbutt, N.C.1    Norman, A.2    Cunningham, D.3    Iveson, T.4    Seymour, M.5    Hickish, T.6    Harper, P.7    Maisey, N.8    Mochlinski, K.9    Prior, Y.10    Hill, M.11
  • 48
    • 0003322126 scopus 로고    scopus 로고
    • Preoperative radiotherapy and TME-surgery for rectal cancer: Detailed analyses in relation to quality control in a randomized trial
    • Van de Velde CJ (2002) Preoperative radiotherapy and TME-surgery for rectal cancer: detailed analyses in relation to quality control in a randomized trial. Proc Am Soc Clin Oncol 21: 127a
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Van De Velde, C.J.1
  • 50
    • 0036122750 scopus 로고    scopus 로고
    • Prognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer
    • Wibe A, Rendedal PR, Svensson E, Norstein J, Eide TJ, Myrvold HE, Soreide O (2002) Prognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer. Br J Surg 89: 327-334
    • (2002) Br J Surg , vol.89 , pp. 327-334
    • Wibe, A.1    Rendedal, P.R.2    Svensson, E.3    Norstein, J.4    Eide, T.J.5    Myrvold, H.E.6    Soreide, O.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.