Improved survival and reduction in local failure rates after preoperative radiotherapy: Evidence for the generalizability of the results of Swedish Rectal Cancer Trial

Annals of Surgery

Volumn 229, Issue 4, 1999, Pages 493-497

  Dahlberg, Michael ^a   Glimelius, Bengt ^a   Påhlman, Lars ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER RECURRENCE; CANCER REGISTRY; CANCER SURGERY; CANCER SURVIVAL; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RADIATION DOSE; RECTUM CANCER; SURVIVAL RATE; TREATMENT FAILURE;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PREOPERATIVE CARE; RADIOTHERAPY, ADJUVANT; RECTAL NEOPLASMS; REGISTRIES; RETROSPECTIVE STUDIES; SURVIVAL RATE; SWEDEN;

EID: 0033504317     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000658-199904000-00007     Document Type: Article

References (23)

1. Gérard A, Buyse M, Nordlinger B, et al. Preoperative radiotherapy as adjuvant treatment in rectal cancer. Ann Surg 1988; 208:606-614.
2. Marsh PJ, James RD, Schofield PF. Adjuvant preoperative radiotherapy for locally advanced rectal carcinoma: results of a prospective randomized trial. Dis Colon Rectum 1994; 37:1205-1214.
3. Swedish Rectal Cancer Trial. Local recurrence rate in a randomized multicentre trial of preoperative radiotherapy compared to surgery alone in resectable rectal carcinoma. Eur J Surg 1996; 162:397-402.
4. Stockholm Rectal Cancer Study Group. Preoperative short-term radiation therapy in operable rectal carcinoma. A prospective randomized trial. Cancer 1990; 66:49-55.
5. Horn A, Halvorsen J, Dahl O. Preoperative radiotherapy in operable rectal cancer. Dis Colon Rectum 1990; 33:823-828.
6. Goldberg PA, Nicholls RJ, Porter NH, Love S, Grimsey JE. Long-term results of a randomized trial of short-course low-dose adjuvant preoperative radiotherapy for rectal cancer: reduction in local treatment failure. Eur J Cancer 1994; 30A: 1602-1606.
7. Fisher B, Wolmark N, Rockette H, et al. Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: results from NSABP Protocol R-01. J Natl Cancer Inst 1988; 80:21-29.
8. Balslev I, Pedersen M, Teglbjaerg PS, et al. Postoperative radiotherapy in Dukes B and C carcinoma of the rectum and rectosigmoid. A randomized multicenter study. Cancer 1986; 58:22-28.
9. Gastro-Intestinal Tumor Study Group. Prolongation of the disease-free interval in surgically treated rectal carcinoma. N Engl J Med 1985; 312:1465-1472.
10. Treurinet-Donker AD, van Putten WLJ, Wereldsma JCJ, et al. Post-operative radiation therapy for rectal cancer. Cancer 1991; 67:2042.
11. Påhlman L, Glimelius B. Pre-and postoperative radiotherapy in rectal and rectosigmoid carcinoma: report from a multicenter trial. Ann Surg 1990; 211:187-195.
12. Swedish Rectal Cancer Trial. Improved survival with preoperative radiotherapy in resectable rectal cancer. N Engl J Med 1997; 336:980-987.
13. Swedish Rectal Cancer Trial. Initial report from a Swedish multicentre study examining the role of preoperative irradiation in the treatment of patients with resectable rectal carcinoma. Br J Surg 1993; 80:1333-1335.
14. Mattsson B, Wallgren A. Completeness of the Swedish Cancer Register. Non-notified cancer cases on death certificates in 1978. Acta Radiol Oncol 1984; 23:305-313.
15. Buyse M, Zeleniuch-Jacuotte A, Chalmes TC. Adjuvant therapy of colorectal cancer. Why we still don't know. JAMA 1988; 259:3571-3578.
16. Glimelius B, Isacsson U, Jung B, Påhlman L. Radiotherapy in addition to radical surgery in rectal cancer: evidence for a dose-response effect favoring preoperative treatment. Int J Radiat Oncol Biol Phys 1997; 37:281-287.
17. Hojo K, Sawada T, Moriya Y. An analysis of survival and voiding, sexual function after wide ileopelvic lymphadectomy in patients with carcinoma of the rectum, compared with conventional lymphadectomy. Dis Colon Rectum 1989; 32:128-133.
18. MacFarlane J, Ryall R, Heald R. Mesorectal excision for rectal cancer. Lancet 1993; 341:457-460.
19. Heald RJ, Karanjia ND. Results of radical surgery for rectal cancer. World J Surg 1992; 16:848-857.
20. Krook JE, Moertel CG, Gunderson LL, et al. (NCCTG). Effective surgical adjuvant therapy for high-risk rectal cancer. N Engl J Med 1991; 324:709-715.
21. Medical Research Council Rectal Cancer Working Party. Randomised trial of surgery alone versus radiotherapy followed by surgery for potentially operable locally advanced rectal cancer. Lancet 1996; 348(9042):1605-1610.
22. Medical Research Council Rectal Cancer Working Party. Randomised trial of surgery alone versus surgery followed by radiotherapy for mobile cancer of the rectum. Lancet 1996; 348(9042):1610-1614.
23. Påhlman L, Glimelius B. The value of adjuvant radio(chemo)therapy for rectal cancer. Eur J Cancer 1995; 31A:1347-1350.