메뉴 건너뛰기




Volumn 51, Issue 5, 2003, Pages 385-394

In vivo antitumor activity of S16020, a topoisomerase II inhibitor, and doxorubicin against human brain tumor xenografts

Author keywords

Doxorubicin; Glioblastoma; Medulloblastoma; MRP1; Nitrosourea

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; FOTEMUSTINE; N (2 DIMETHYLAMINOETHYL) 9 HYDROXY 5,6 DIMETHYL 6H PYRIDO[4,3 B]CARBAZOLE 1 CARBOXAMIDE;

EID: 0038018597     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-003-0584-1     Document Type: Article
Times cited : (20)

References (35)
  • 1
    • 0028070776 scopus 로고
    • Possible involvement of multidrug-resistance-associated protein (MRP) gene expression in spontaneous drug resistance to vincristine, etoposide and adriamycin in human glioma cells
    • Abe T, Hasegawa S, Taniguchi K, Yokomizo A, Kuwano T, Ono M, Mori T, Hori S, Kohno K, Kuwano M (1994) Possible involvement of multidrug-resistance-associated protein (MRP) gene expression in spontaneous drug resistance to vincristine, etoposide and adriamycin in human glioma cells. Int J Cancer 58:860-864
    • (1994) Int J Cancer , vol.58 , pp. 860-864
    • Abe, T.1    Hasegawa, S.2    Taniguchi, K.3    Yokomizo, A.4    Kuwano, T.5    Ono, M.6    Mori, T.7    Hori, S.8    Kohno, K.9    Kuwano, M.10
  • 4
    • 0028043795 scopus 로고
    • Expression of the multidrug resistance-associated protein (MRP) gene correlates with amplification and overexpression of the N-myc oncogene in childhood neuroblastoma
    • Bordow SB, Haber M, Madafiglio J, Cheung B, Marshall GM, Norris MD (1994) Expression of the multidrug resistance-associated protein (MRP) gene correlates with amplification and overexpression of the N-myc oncogene in childhood neuroblastoma. Cancer Res 54:5036-5040
    • (1994) Cancer Res , vol.54 , pp. 5036-5040
    • Bordow, S.B.1    Haber, M.2    Madafiglio, J.3    Cheung, B.4    Marshall, G.M.5    Norris, M.D.6
  • 5
    • 0029552544 scopus 로고
    • Multidrug resistance gene expression in childhood medulloblastoma: Correlation with clinical outcome and DNA ploidy in 29 patients
    • Chou PM, Reyes-Mugica M, Barquin N, Yasuda T, Tan X, Tomita T (1995) Multidrug resistance gene expression in childhood medulloblastoma: correlation with clinical outcome and DNA ploidy in 29 patients. Pediatr Neurosurg 23:283-291
    • (1995) Pediatr Neurosurg , vol.23 , pp. 283-291
    • Chou, P.M.1    Reyes-Mugica, M.2    Barquin, N.3    Yasuda, T.4    Tan, X.5    Tomita, T.6
  • 6
    • 0029944362 scopus 로고    scopus 로고
    • Tumor suppressor genes and medulloblastoma
    • Cogen PH, McDonald JD (1996) Tumor suppressor genes and medulloblastoma. J Neurooncol 29:103-112
    • (1996) J Neurooncol , vol.29 , pp. 103-112
    • Cogen, P.H.1    McDonald, J.D.2
  • 7
    • 0038134267 scopus 로고
    • Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats
    • Cowan KH, Batist G, Tulpule A, Sinha BK, Myers CE (1986) Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats. Proc Natl Acad Sci U S A 83:9328-9332
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 9328-9332
    • Cowan, K.H.1    Batist, G.2    Tulpule, A.3    Sinha, B.K.4    Myers, C.E.5
  • 11
    • 0023638001 scopus 로고
    • The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit
    • Gussow D, Rein R, Ginjaar I, Hochstenbach F, Seemann G, Kottman A, Ploegh HL (1987) The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit. J Immunol 139:3132-3138
    • (1987) J Immunol , vol.139 , pp. 3132-3138
    • Gussow, D.1    Rein, R.2    Ginjaar, I.3    Hochstenbach, F.4    Seemann, G.5    Kottman, A.6    Ploegh, H.L.7
  • 16
    • 0031934818 scopus 로고    scopus 로고
    • S16020-2, a new highly cytotoxic antitumor olivacine derivative: DNA interaction and DNA topoisomerase II inhibition
    • Le Mée S, Pierre A, Markovits J, Atassi G, Jacquemin-Sablon A, Saucier JM (1998) S16020-2, a new highly cytotoxic antitumor olivacine derivative: DNA interaction and DNA topoisomerase II inhibition. Mol Pharmacol 53:213-220
    • (1998) Mol Pharmacol , vol.53 , pp. 213-220
    • Le Mée, S.1    Pierre, A.2    Markovits, J.3    Atassi, G.4    Jacquemin-Sablon, A.5    Saucier, J.M.6
  • 18
    • 0034284484 scopus 로고    scopus 로고
    • Modulation of daunorubicin cellular resistance by combination of P-glycoprotein blockers acting on drug efflux and intracellular drug sequestration in Golgi vesicles
    • Merlin JL, Bour-Dill C, Marchal S, Ramacci C, Poullain MG, Giroux B (2000) Modulation of daunorubicin cellular resistance by combination of P-glycoprotein blockers acting on drug efflux and intracellular drug sequestration in Golgi vesicles. Cytometry 41:62-72
    • (2000) Cytometry , vol.41 , pp. 62-72
    • Merlin, J.L.1    Bour-Dill, C.2    Marchal, S.3    Ramacci, C.4    Poullain, M.G.5    Giroux, B.6
  • 21
    • 0031888205 scopus 로고    scopus 로고
    • Rare occurrence of inactivating p53 gene mutations in primary non-astrocytic tumors of the central nervous system: Reappraisal by yeast functional assay
    • Nozaki M, Tada M, Matsumoto R, Sawamura Y, Abe H, Iggo RD (1998) Rare occurrence of inactivating p53 gene mutations in primary non-astrocytic tumors of the central nervous system: reappraisal by yeast functional assay. Acta Neuropathol (Berl) 95:291-296
    • (1998) Acta Neuropathol (Berl) , vol.95 , pp. 291-296
    • Nozaki, M.1    Tada, M.2    Matsumoto, R.3    Sawamura, Y.4    Abe, H.5    Iggo, R.D.6
  • 22
    • 0031717670 scopus 로고    scopus 로고
    • Circumvention of P-glycoprotein-mediated multidrug resistance by S16020-2: Kinetics of uptake and efflux in sensitive and resistant cell lines
    • Pierre A, Leonce S, Perez V, Atassi G (1998) Circumvention of P-glycoprotein-mediated multidrug resistance by S16020-2: kinetics of uptake and efflux in sensitive and resistant cell lines. Cancer Chemother Pharmacol 42:454-460
    • (1998) Cancer Chemother Pharmacol , vol.42 , pp. 454-460
    • Pierre, A.1    Leonce, S.2    Perez, V.3    Atassi, G.4
  • 23
    • 0034059501 scopus 로고    scopus 로고
    • Enhanced delivery improves the efficacy of a tumor-specific doxorubicin immunoconjugate in a human brain tumor xenograft model
    • Remsen LG, Trail PA, Hellstrom I, Hellstrom KE, Neuwelt EA (2000) Enhanced delivery improves the efficacy of a tumor-specific doxorubicin immunoconjugate in a human brain tumor xenograft model. Neurosurgery 46:704-709
    • (2000) Neurosurgery , vol.46 , pp. 704-709
    • Remsen, L.G.1    Trail, P.A.2    Hellstrom, I.3    Hellstrom, K.E.4    Neuwelt, E.A.5
  • 24
    • 0029585915 scopus 로고
    • Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: Biodistribution and therapeutic efficacy
    • Siegal T, Horowitz A, Gabizon A (1995) Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: biodistribution and therapeutic efficacy. J Neurosurg 83:1029-1037
    • (1995) J Neurosurg , vol.83 , pp. 1029-1037
    • Siegal, T.1    Horowitz, A.2    Gabizon, A.3
  • 25
    • 0038294172 scopus 로고    scopus 로고
    • Effect of taxol on apoptosis in a sensitive and resistant human small cell lung carcinoma (A549)
    • Solis-Recendez MG, Khayat D, Batist G (2000) Effect of taxol on apoptosis in a sensitive and resistant human small cell lung carcinoma (A549) (abstract). Proc Am Assoc Cancer Res 41:302
    • (2000) Proc Am Assoc Cancer Res , vol.41 , pp. 302
    • Solis-Recendez, M.G.1    Khayat, D.2    Batist, G.3
  • 28
    • 0003377172 scopus 로고    scopus 로고
    • Guidelines for the Welfare of Animals in Experimental Neoplasia (second edition)
    • United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR) (1998) Guidelines for the Welfare of Animals in Experimental Neoplasia (second edition). Br J Cancer 77:1-10
    • (1998) Br J Cancer , vol.77 , pp. 1-10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.