A TRPV family ion channel required for hearing in Drosophila

Nature

Volumn 424, Issue 6944, 2003, Pages 81-84

  Kim, Janghwan ^a,b   Chung, Yun Doo ^c,d   Park, Dae Young ^a   Choi, SooKyung ^a   Shin, Dong Wook ^a   Soh, Heun ^e   Lee, Hye Won ^a   Son, Wonseok ^a   Yim, Jeongbin ^f   Park, Chul Seung ^e   Kernan, Maurice J ^c,d   Kim, Changsoo ^a  

^a Iljin Nanotech Co Ltd   (South Korea)

^b Chungnam National University   (South Korea)

^c STONY BROOK UNIVERSITY   (United States)

^d Stony Brook University   (United States)

^e Gwangju Institute of Science and Technology (GIST)   (South Korea)

^f Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CALCIUM; CELL CULTURE; CELLS; PROTEINS; TRANSDUCERS;

AUDITORY SYSTEMS;

SENSORY PERCEPTION;

CALCIUM ION; CAPSAICIN; EGTAZIC ACID; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEIN; ION CHANNEL; MALTOSE BINDING PROTEIN; PROTEIN NAN; PROTEIN TRPV; UNCLASSIFIED DRUG; VANILLOID RECEPTOR;

INSECT; SENSORY SYSTEM;

ANIMAL CELL; ARTICLE; AUDITORY SYSTEM; CAENORHABDITIS ELEGANS; CALCIUM TRANSPORT; CHO CELL; CONTROLLED STUDY; DROSOPHILA; EVOKED RESPONSE; HEARING; IN VIVO STUDY; MECHANORECEPTOR; NONHUMAN; OSMOTIC STRESS; PATCH CLAMP; PRIORITY JOURNAL; RECEPTOR POTENTIAL; SENSORY NERVE CELL; SOUND;

AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; CHO CELLS; CRICETINAE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EVOLUTION, MOLECULAR; GENE DELETION; GENE EXPRESSION PROFILING; HEARING; MOLECULAR SEQUENCE DATA; NEURONS; OSMOTIC PRESSURE; PATCH-CLAMP TECHNIQUES;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS; INSECTA;

EID: 0038004472     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01733     Document Type: Article

References (27)

1. Yager, D. D. Structure, development, and evolution of insect auditory systems. Microsc. Res. Tech. 47, 380-400 (1999).
2. Eberl, D. F. Feeling the vibes: chordotonal mechanisms in insect hearing. Curr. Opin. Neurobiol. 9, 389-393 (1999).
3. Caldwell, J. C. & Eberl, D. F. Towards a molecular understanding of Drosophila hearing. J. Neurobiol. 53, 172-189 (2002).
4. Strassmaier, M. & Gillespie, P. G. The hair cell's transduction channel. Curr. Opin. Neurobiol 12, 380-386 (2002).
5. Kernan, M. J., Cowan, D. & Zuker, C. Genetic dissection of mechanosensory transduction: mechanoreception-defective mutations of Drosophila. Neuron 12, 1195-1206 (1994).
6. Walker, R., Willingham, A. & Zuker, C. A Drosophila mechanosensory transduction channel. Science 287, 2229-2234 (2000).
7. Eberl, D., Hardy, R. & Kernan, M. J. Genetically similar transduction mechanisms for touch and hearing in Drosophila. J. Neurosci. 20, 5981-5988 (2000).
8. Gunthorpe, M. J., Benham, C. D., Randall, A. & Davis, J. B. The diversity in the vanilloid (TRPV) receptor family of ion channels. Trends Pharmacol. Sci. 23, 183-191 (2002).
9. Benham, C. D., Davis, J. B. & Randall, A. D. Vanilloid and TRP channels: a family of lipid-gated cation channels. Neuropharmacology 42, 873-888 (2002).
10. Colbert, H., Smith, T. & Bargmann, C. OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans. J. Neurosci 17, 8259-8369 (1997).
11. Tobin, D. et al. Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons. Neuron 35, 307-318 (2002).
12. Caterina, M. et al. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389, 816-824 (1997).
13. Caterina, M. J. et al. Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288, 306-313 (2000).
14. Caterina, M. J., Rosen, T. A., Tominaga, M., Brake, A. J. & Iulius, D. A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 398, 436-441 (1999).
15. Liedtke, W. et al. Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell 103, 525-535 (2000).
16. Adams, M. et al. The genome sequence of Drosophila melanogaster. Science 287, 2185-2195 (2000).
17. Littleton, J. T. & Ganetzky, B. Ion channels and synaptic organization: analysis of the Drosophila genome. Neuron 26, 33-43 (2000).
18. Strotmann, R. Harteneck, C., Nunnenmacher, K., Schuhz, G. & Plant, T. D. OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity. Nature Cell. Biol. 2, 695-702 (2000).
19. Vandaele, C., Coulon-Bublex, M., Couble, P. & Durand, B. Drosophila regulatory factor X is an embryonic type 1 sensory neuron marker also expressed in spermatids and in the brain of Drosophila. Mech. Dev. 103, 159-162 (2001).
20. Dubruille, R. et al. Drosophila regulatory factor X is necessary for ciliated sensory neuron differentiation. Development 129, 5487-5498 (2002).
21. Chung, Y., Zhu, J., Han, Y. & Kernan, M. nompA encodes a PNS-specific, ZP-domain protein required to connect mechanosensory dendrites to sensory structures. Neuron 29, 415-428 (2001).
22. Xu, H. et al. Regulation of a TRP channel by tyrosine phosphorylation: Src family kinase-dependent phosphorylation of TRPV4 on Y253 mediates its response to hypotonic stress. J. Biol. Chem. 278, 11520-11527 (2003).
23. Guler, A. D. et al. Heat-evoked activation of the ion channel, TRPV4. J. Neurosci. 22, 6408-6414 (2002).
24. Watanabe, H. et al. Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives. J. Biol. Chem. 277, 13569-13577 (2002).
25. Moller, S., Croning, M. D. & Apweiler, R. Evaluation of methods for the prediction of membrane spanning regions. Bioinformatics 17, 646-653 (2001).
26. Schultz, J., Milpetz, F., Bork, P. & Ponting, C. P. SMART, a simple modular architecture research tool: Identification of signalling domains. Proc. Natl Acad. Sci. USA 95, 5857-5864 (1998).
27. Brand, A. H. & Perrimon, N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415 (1993).