메뉴 건너뛰기




Volumn 13, Issue 14, 2003, Pages 2385-2388

Synthesis and inhibitory activity of ubiquinone-acetogenin hybrid inhibitor with bovine mitochondrial complex I

Author keywords

[No Author keywords available]

Indexed keywords

ACETOGENIN; GAMMA LACTONE DERIVATIVE; Q ACETIGENIN; UBIQUINOL CYTOCHROME C REDUCTASE; UBIQUINONE; UNCLASSIFIED DRUG;

EID: 0038003853     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00439-6     Document Type: Article
Times cited : (32)

References (24)
  • 8
    • 85031157833 scopus 로고    scopus 로고
    • note
    • 50 values of mucocin and squamocin D are about 30- and 8-fold larger than that of rotenone, the inhibitory potency of which is about 1/10th that of bullatacin (refs 4-6).
  • 14
    • 85031150883 scopus 로고    scopus 로고
    • + calcd 692.5227, found 692.5247.
  • 16
    • 85031153471 scopus 로고    scopus 로고
    • 50 values were averaged from two independent experiments.
  • 19
    • 85031145175 scopus 로고    scopus 로고
    • Taking into consideration the amphiphilic character of compound 2, it is very likely that the apparent inhibition was brought about by nonspecific perturbation of the membrane (or the enzyme) structure due to high concentration.
  • 22
    • 85031149168 scopus 로고    scopus 로고
    • d value of bullatacin is 2-5 nM (ref 5).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.