An efficient approach to 3,4-disubstituted pyridin-2-ones. Formal synthesis of mappicine ketone

Journal of Organic Chemistry

Volumn 68, Issue 14, 2003, Pages 5688-5691

  Lin, Ching H ^a   Tsai, Min R ^a   Wang, Yung S ^a   Chang, Nein C ^a  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL HALIDES;

SODIUM COMPOUNDS; SYNTHESIS (CHEMICAL);

KETONES;

3,4 DIHYDRO 3 TOSYLPYRIDIN 2 ONE; ALKALOID; CAMPTOTHECIN; HETEROCYCLIC COMPOUND; KETONE; MAPPICINE; NATURAL PRODUCT; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

INDOLIZINES; PIPERIDONES; PYRIDONES; QUINOLINES; SULFONES;

EID: 0037999814     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo034042s     Document Type: Article

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14. For recent examples of the synthesis of functionalized 2-pyridones, see: (a) Bondavalli, F.; Bruno, O.; Presti, E. L.; Menozzi, G.; Mosti, L. Synthesis 1999, 1169. (b) Perrin, S.; Monnier, K.; Laude, B.; Kubicki, M.; Blacque, O. Eur. J. Org. Chem. 1999, 297, 7. (c) Furukawa, I.; Fujisawa, H.; Kawazome, M.; Nakai, Y.; Ohta, T. Synthesis 1998, 1715. (d) Ciufolini, M. A.; Bouchu, D.; Rousset, L.; Penlou, S.; Narkunan, K.; Carles, L. J. Org. Chem. 2002, 67, 4304. (e) Shimizu, M.; Ogura, K.; Hachiya, I. Org. Lett. 2002, 4 (16), 2755.
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