Identification of a more potent analogue of the naturally occurring alkaloid huperzine A. Predictive molecular modeling of its interaction with AChE

Journal of the American Chemical Society

Volumn 118, Issue 46, 1996, Pages 11357-11362

  Kozikowski, Alan P ^a   Campiani, Giuseppe ^b   Sun, Li Qiang ^c   Wang, Shaomeng ^a   Saxena, Ashima ^d   Doctor, Bhupendra P ^d  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF SIENA   (Italy)

^c OHIO STATE UNIVERSITY   (United States)

^d WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; HUPERZINE A; HUPERZINE A DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME BINDING; ENZYME INHIBITION; ENZYME STRUCTURE; MOLECULAR DYNAMICS; MOLECULAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; TORPEDO;

EID: 0029909228     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9622822     Document Type: Article

References (27)

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