Regulation of ania-6 splice variants by distinct signaling pathways in striatal neurons

Journal of Neurochemistry

Volumn 86, Issue 1, 2003, Pages 153-164

  Sgambato, Véronique ^a,b,e   Minassian, Raia ^a   Nairn, Angus C ^b,c   Hyman, Steven E ^a,d  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HARVARD UNIVERSITY   (United States)

^e INSERM   (France)

Author keywords

Cyclin; Dopamine; Glutamate; Signaling; Splicing; Striatum

Indexed keywords

ANIA 6; BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM CHANNEL L TYPE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLINE; FORSKOLIN; GLUTAMIC ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTRANSMITTER; PROTEIN KINASE (CALCIUM,CALMODULIN); UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG DEPENDENCE; GENE EXPRESSION; GENETIC TRANSCRIPTION; MEMORY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STRIATE CORTEX;

ALTERNATIVE SPLICING; ANIMALS; BINDING SITES; CALCIUM; CELLS, CULTURED; CORPUS STRIATUM; CYCLINS; ENZYME INHIBITORS; GLUTAMIC ACID; MACROMOLECULAR SUBSTANCES; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; PC12 CELLS; PHOSPHORYLATION; POTASSIUM CHLORIDE; PROMOTER REGIONS (GENETICS); PURINES; RATS; RATS, SPRAGUE-DAWLEY; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

ANIMALIA;

EID: 0037971214     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01816.x     Document Type: Article

References (51)

1. Ahn S., Olive M., Aggarwal S., Krylov D., Ginty D. D. and Vinson C. (1998) A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos. Mol. Cell. Biol. 18, 967-977.
2. Berke J. D. and Hyman S. E. (2000) Addiction, dopamine, and the molecular mechanisms of memory. Neuron 25, 515-532.
3. Berke J. D., Paletzki R. F., Aronson G. J., Hyman S. E. and Gerfen C. R. (1998) A complex program of striatal gene expression induced by dopaminergic stimulation. J. Neurosci. 18, 5301-5310.
4. Berke J. D., Sgambato V., Zhu P. P., Lavoie B., Vincent M., Krause M. and Hyman S. E. (2001) Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin. Neuron 32, 277-287.
5. 2+)- and stimulus duration-dependent switch for hippocampal gene expression. Cell 87, 1203-1214.
6. Black D. L. (1998) Splicing in the inner ear: a familiar tune, but what are the instruments? Neuron 20, 165-168.
7. Bottai D., Guzowski J. F., Schwarz M. K., Kang S. H., Xiao B., Lanahan A., Worley P. F. and Seeburg P. H. (2002) Synaptic activity-induced conversion of intronic to exonic sequence in Homer 1 immediate early gene expression. J. Neurosci. 22, 167-175.
8. Cai D., Shen Y., De Bellard M., Tang S. and Filbin M. T. (1999) Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism. Neuron 22, 89-101.
9. Daoud R., Da Penha Berzaghi M., Siedler F., Hubener M. & Stamm S. (1999) Activity-dependent regulation of alternative splicing patterns in the rat brain. Eur. J. Neurosci. 11, 788-802.
10. Deisseroth K., Heist E. K. and Tsien R. W. (1998) Translocation of calmodulin to the nucleus supports CREB phosphorylation in hippocampal neurons. Nature 392, 198-202.
11. Dickinson L. A., Edgar A. J., Ehley J. and Gotiesfeld J. M. (2002) Cyclin L is an RS domain protein involved in pre-mRNA splicing. J. Biol. Chem. 277, 25465-25473.
12. Dolmetsch R. E., Pajvani U., Fife K., Spotts J. M. and Greenberg M. E. (2001) Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway. Science 294, 333-339.
13. Dredge K., Polydorides A. D. and Darnell R. B. (2001) The splice of life: alternative splicing and neurological disease. Nature Rev. Neurosci. 2, 43-50.
14. Gau D., Lemberger T., von Gall C., Kretz O., Le Minh N., Gass P., Schmid W., Schibler U., Korf H. W. and Schutz G. (2002) Phosphorylation of CREB Ser142 regulates light-induced phase shifts of the circadian clock. Neuron 34, 245-253.
15. Ghosh A. and Greenberg M. E. (1995) Calcium signaling in neurons: molecular mechanisms and cellular consequences. Science 268, 239-247.
16. Ginty D. D., Bonni A. and Greenberg M. E. (1994) Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell 77, 713-725.
17. 2+/calmodulin-regulated protein phosphatase, calcineurin. Neuroscience 62, 695-705.
18. Grabowski P. J. and Black D. L. (2001) Alternative RNA splicing in the nervous system. Prog. Neurobiol. 65, 289-308.
19. Graybiel A. M., Moratalla R. and Robertson H. A. (1990) Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum. Proc. Natl Acad. Sci. USA 87, 6912-6916.
20. Hardingham G. E., Arnold F. J. and Bading H. (2001) Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity. Nat. Neurosci. 4, 261-267.
21. Hardingham G. E., Chawla S., Johnson C. M. and Bading H. (1997) Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression. Nature 385, 260-265.
22. Hope B. T., Nye H. E., Kelz M. B., Self D. W., Iadarola M. J., Nakabeppu Y., Duman R. S. and Nestler E. J. (1994) Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments. Neuron 13, 1235-1244.
23. Hosoi T., Uchiyama M., Okumura E., Saito T., Ishiguro K., Uchida T., Okuyama A., Kishimoto T. and Hisanaga S. (1995) Evidence for cdk5 as a major activity phosphorylating tau protein in porcine brain extract. J. Biochem. 117, 741-749.
24. van der Houven van Oordt W., Diaz-Meco M. T., Lozano J., Krainer A. R., Moscat J. and Cacares J. F. (2000) The MKK (3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation. J. Cell Biol. 149, 307-316.
25. Hu D., Mayeda A., Trembley J. H., Lahti J. M. and Kidd V. J. (2003) CDK11 complexes promote pre-mRNA splicing. J. Biol. Chem. 278, 8623-8629.
26. Hyman S. E. (1996) Addiction to cocaine and amphetamine. Neuron 16, 901-904.
27. Jensen K. B., Dredge B. K., Stefani G., Zhong R., Buckanovich R. J., Okano H. J., Yang Y. Y. L. and Darnell R. B. (2000) Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability. Neuron 25, 359-371.
28. Kitagawa M., Okabe T., Ogino H., Matsumoto H., Suzuki-Takahashi I., Kokubo T., Higashi H., Saitoh S., Taya Y., Yasuda H., Ohba Y., Nishimura S., Tanaka N. and Okuyama A. (1993) Butyrolactone I, a selective inhibitor of cdk2 and cdc2 kinase. Oncogene 8, 2425-2432.
29. Knockaert M., Lenormand P., Gray N., Schultz P., Pouyssegur J. and Meijer L. (2002) p42/p44 MAPKs are intracellular targets of the CDK inhibitor purvalanol. Oncogene 21, 6413-6424.
30. Konradi C., Cole R. L., Heckers S. and Hyman S. E. (1994) Amphetamine regulates gene expression in rat striatum via transcription factor CREB. J. Neurosci. 14, 5623-5634.
31. Kornhauser J. M., Cowan C. W., Shaywitz A. J., Dolmetsch R. E., Griffith E. C., Hu L. S., Haddad C., Xia Z. and Greenberg M. E. (2002) CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events. Neuron 34, 221-233.
32. Koushika S. P., Lisbin M. J. and White K. (1996) ELAV, a Drosophila neuron-specific protein, mediates the generation of an alternatively spliced neural protein isoform. Curr Biol. 6, 1634-1641.
33. Kuppers E., Sabolek M., Anders U., Pilgrim C. and Beyer C. (2000) Developmental regulation of glutamic acid decarboxylase mRNA expression and splicing in the rat striatum by dopamine. Brain Res. Mol. Brain Res. 81, 19-28.
34. Kwok R. P., Lundblad J. R., Chrivia J. C., Richards J. P., Bachinger H. P., Brennan R. G., Roberts S. G., Green M. R. and Goodman R. H. (1994) Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 21, 223-226.
35. Matter N., Herrlich P. and Konig H. (2002) Signal-dependent regulation of splicing via phosphorylation of Sam68. Nature 420, 691-695.
36. Meijer L., Borgne A., Mulner O., Chong J. P., Blow J. J., Inagaki N., Inagaki M., Delcros J. G. and Moulinoux J. P. (1997) Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. Eur. J. Biochem. 243, 527-536.
37. Nakamura Y., Okuno S., Sato F. and Fujisawa H. (1995) An immunocytochemical study of calcium/calmodulin-dependent protein kinase IV in the rat central nervous system: light and electron microscopic observations. Neuroscience 68, 181-194.
38. Paul S., Nairn A. C., Wang P. and Lombroso P. J. (2003) NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nat Neurosci. 6, 34-42.
39. Roberts G. C. and Smith C. W. (2002) Alternative splicing: combinatorial output from the genome. Curr Opin. Chem. Biol. 6, 375-383.
40. Rosen L. B., Ginty D. D., Weber M. J. and Greenberg M. E. (1994) Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron 12, 1207-1221.
41. Rudolph B., Saffrich R., Zwicker J., Henglein B., Muller R., Ansorge W. and Eilers M. (1996) Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis. EMBO J. 15, 3065-3076.
42. Sharma P., Veeranna Sharma M., Amin N. D., Sihag R. K., Grant P., Ahn N., Kulkami A. B. and Pant H. C. (2002) Phosphorylation of MEK1 by cdk5/p35 downregulates the mitogen-activated protein kinase pathway. J. Biol. Chem. 277, 528-534.
43. Sheng M., McFadden G. and Greenberg M. E. (1990) Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 4, 571-582.
44. Sun P. and Maurer R. A. (1995) An inactivating point mutation demonstrates that interaction of cAMP response element binding protein (CREB) with the CREB binding protein is not sufficient for transcriptional activation. J. Biol. Chem. 270, 7041-7044.
45. 2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes Dev. 8, 2527-2539.
46. Wang X., Bruderer S., Rafi Z., Xue J., Milburn P. J., Kramer A. and Robinson P. J. (1999) Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly. EMBO J. 18, 4549-4559.
47. Weg-Remers S., Ponta H., Herrlich P. and Konig H. (2001) Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway. EMBO J. 20, 4194-4203.
48. Xie J. and Black D. L. (2001) A CaMK IV-responsive RNA element mediates depolarization-induced alternative splicing of ion channels. Nature 410, 936-939.
49. Xing J., Ginty D. D. and Greenberg M. E. (1996) Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science 273, 959-963.
50. Yan Z., Chi P., Bibb J. A., Ryan T. A. and Greengard P. (2002) Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons. J. Physiol. 540, 761-770.
51. 2+. Curr. Biol. 6, 1642-1652.