메뉴 건너뛰기




Volumn 42, Issue 11, 2002, Pages 1077-1081

Parkin gene: Its mutations and function

(1)  Hattori, Nobutaka a  

a NONE

Author keywords

Lawy bodies; Parkin; Ubiquitin ligase; Ubiquitin proteasome system; Young onset Parkinson's disease

Indexed keywords

ALPHA SYNUCLEIN; ALPHA SYNUCLEIN 22; PARKIN; PEAL RECEPTOR; PROTEIN; PROTEIN CDCREL 1; SYNPHILIN 1; UNCLASSIFIED DRUG;

EID: 0037948961     PISSN: 0009918X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (4)

References (11)
  • 1
    • 0015590978 scopus 로고
    • Paralysis agitans of early onset with marked diurnal fluctuation of symptoms
    • Yamamura Y, Sobue I, Ando K, et al: Paralysis agitans of early onset with marked diurnal fluctuation of symptoms. Neurology 23: 239-244, 1973
    • (1973) Neurology , vol.23 , pp. 239-244
    • Yamamura, Y.1    Sobue, I.2    Ando, K.3
  • 2
    • 0032499264 scopus 로고    scopus 로고
    • Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
    • Kitada T, Asakawa S, Hattori N, et al: Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392: 605-608, 1998
    • (1998) Nature , vol.392 , pp. 605-608
    • Kitada, T.1    Asakawa, S.2    Hattori, N.3
  • 3
    • 18244412384 scopus 로고    scopus 로고
    • Molecular analysis of a novel ubiquitin-like protein (PARKIN) gene in Japanese families with AR-JP: Evidencce of homozygous deletions in the PARKIN gene in affected individuals
    • Hattori N, Kitada T, Matsumine H, et al: Molecular analysis of a novel ubiquitin-like protein (PARKIN) gene in Japanese families with AR-JP: evidencce of homozygous deletions in the PARKIN gene in affected individuals. Ann Neurol 44: 935-941, 1998
    • (1998) Ann Neurol , vol.44 , pp. 935-941
    • Hattori, N.1    Kitada, T.2    Matsumine, H.3
  • 4
    • 0342368772 scopus 로고    scopus 로고
    • Association between early-onset Parkinson's disease and mutations in the parkin gene
    • Lüking CB, Durr A, Bonifati V, et al: Association between early-onset Parkinson's disease and mutations in the parkin gene. N Engl J Med 342: 1560-1567, 2000
    • (2000) N Engl J Med , vol.342 , pp. 1560-1567
    • Lüking, C.B.1    Durr, A.2    Bonifati, V.3
  • 5
    • 0034805921 scopus 로고    scopus 로고
    • The genomic structure and promoter region of the human parkin gene
    • Asakawa S, Tsunematsu K, Takayanagi A, et al: The genomic structure and promoter region of the human parkin gene. Biochem Biophys Res Communn 286: 863-868, 2001
    • (2001) Biochem Biophys Res Communn , vol.286 , pp. 863-868
    • Asakawa, S.1    Tsunematsu, K.2    Takayanagi, A.3
  • 6
    • 0033933048 scopus 로고    scopus 로고
    • Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
    • Shimura H, Hattori N, Kubo S, et al: Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet 25: 302-305, 2000
    • (2000) Nat Genet , vol.25 , pp. 302-305
    • Shimura, H.1    Hattori, N.2    Kubo, S.3
  • 7
    • 0034700158 scopus 로고    scopus 로고
    • Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
    • Zhang Y, Gao J, Chung KK, et al: Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc Natl Acad Sci USA 97: 13354-13359, 2000
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13354-13359
    • Zhang, Y.1    Gao, J.2    Chung, K.K.3
  • 8
    • 0035967883 scopus 로고    scopus 로고
    • An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of parkin
    • Imai Y, Soda M, Inoue H, et al: An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of parkin. Cell 105: 891-902, 2001
    • (2001) Cell , vol.105 , pp. 891-902
    • Imai, Y.1    Soda, M.2    Inoue, H.3
  • 9
    • 0035854437 scopus 로고    scopus 로고
    • Ubiquitination of a new form of α-synuclein by parkin from human brain: Implications for Parkinson's disease
    • Shimura H, Schlossmacher MG, Hattori N, et al: Ubiquitination of a new form of α-synuclein by parkin from human brain: implications for Parkinson's disease. Science 293: 263-269, 2001
    • (2001) Science , vol.293 , pp. 263-269
    • Shimura, H.1    Schlossmacher, M.G.2    Hattori, N.3
  • 10
    • 0034776095 scopus 로고    scopus 로고
    • Parkin ubiquitinates the α-synuclein-interacting protein, synphilin-1: Implication for Lewy body formation in Parkinson disease
    • Chung KKK, Zhang Y, Lim KL. et al: Parkin ubiquitinates the α-synuclein-interacting protein, synphilin-1: implication for Lewy body formation in Parkinson disease. Nature Med 7: 1144-1150, 2001
    • (2001) Nature Med , vol.7 , pp. 1144-1150
    • Chung, K.K.K.1    Zhang, Y.2    Lim, K.L.3
  • 11
    • 0035664746 scopus 로고    scopus 로고
    • α-synucelin and cytosolic dopamine: Stabilizing a bad situation
    • Suizer D. α-synucelin and cytosolic dopamine: stabilizing a bad situation. Nature Med 7: 1280-1282, 2002
    • (2002) Nature Med , vol.7 , pp. 1280-1282
    • Suizer, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.