Using the polymer partitioning method to probe the thermodynamic activity of poorly water-soluble drugs solubilized in model lipid digestion products

Journal of Pharmaceutical Sciences

Volumn 92, Issue 6, 2003, Pages 1262-1271

  Boyd, Ben J ^a   Porter, Christopher J H ^a   Charman, William N ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Bile salt; Drug absorption; Lipophilic drugs; Polymer partitioning; Solubilization; Thermodynamics

Indexed keywords

BILE SALT; DANAZOL; DIAZEPAM; FATTY ACID; GRISEOFULVIN; PHOSPHATIDYLCHOLINE; POLYMER;

ARTICLE; CALCULATION; DRUG ABSORPTION; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; GASTROINTESTINAL TRACT; LIPOPHILICITY; MICELLE; PARTITION COEFFICIENT; POLYMER PARTITIONING METHOD; POLYMERIZATION; SOLUBILIZATION; THERMODYNAMICS;

EID: 0037945665     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10390     Document Type: Article

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