α-aminoxy acids as building blocks for the oxime and hydroxylamine pseudopeptide links. Application to the synthesis of human elastase inhibitors

Journal of Peptide Science

Volumn 9, Issue 5, 2003, Pages 282-299

  Vanderesse, Regis ^a   Thevenet, Laurent ^a   Marraud, Michel ^a   Boggetto, Nicole ^b   Reboud, Michelle ^b   Corbier, Catherine ^c  

^a LAB DE CHIM PHYS MACROMOLECULAIRE   (France)

^b INSTITUT JACQUES MONOD   (France)

^c Nancy University CNRS   (France)

Author keywords

Elastase; HLE; Hydroxylamine peptides; Inhibition; Oxime peptides; Reduced amidoxy peptides

Indexed keywords

ALDEHYDE DERIVATIVE; ALDOXIME; AMIDE; ELASTASE INHIBITOR; HYDRAZINE DERIVATIVE; HYDROXYLAMINE; KETONE DERIVATIVE; LEUKOCYTE ELASTASE; OXIME; PSEUDOPEPTIDE;

ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; INFRARED SPECTROSCOPY; ISOMERISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ALDEHYDES; AMIDES; AMINO ACID SEQUENCE; AMINO ACIDS; DIMETHYL SULFOXIDE; ENZYME INHIBITORS; HUMANS; HYDROXYLAMINE; KETONES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; OLIGOPEPTIDES; OXIMES; PANCREATIC ELASTASE; PROTEIN CONFORMATION;

EID: 0037941394     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/psc.452     Document Type: Article

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