Reflex sympathetic activation during static exercise is severely impaired in patients with myophosphorylase deficiency

Journal of Physiology

Volumn 548, Issue 3, 2003, Pages 983-993

  Fadel, Paul J ^a   Wang, Zhongyun ^a   Tuncel, Meryem ^a   Watanabe, Hitoshi ^a   Abbas, Aamer ^a   Arbique, Debbie ^a   Vongpatanasin, Wanpen ^a   Haley, Robert W ^b   Victor, Ronald G ^a   Thomas, Gail D ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN; GLYCOGEN PHOSPHORYLASE; LACTIC ACID;

ADULT; BLOOD PRESSURE; CHEMOSENSITIVITY; CLINICAL ARTICLE; COLD PRESSOR TEST; CONTROLLED STUDY; DISEASE SEVERITY; FATIGUE; FEMALE; GLYCOGEN METABOLISM; GLYCOGEN STORAGE DISEASE TYPE 5; GLYCOGENOLYSIS; HAND GRIP; HEART RATE; HUMAN; INTERSTITIUM; MALE; METABOLITE; MICROELECTRODE; MUSCLE; MUSCLE CONTRACTION; MUSCLE EXERCISE; MUSCLE METABOLISM; NERVE CONDUCTION; PRESSOR RESPONSE; PRIORITY JOURNAL; RECORDING; REVIEW; SENSORY NERVE; STATIC EXERCISE; SYMPATHETIC REFLEX; VALSALVA MANEUVER; ADRENERGIC SYSTEM; ANALYSIS OF VARIANCE; ARTICLE; ENZYME METABOLISM; HUMAN TISSUE; MEAN ARTERIAL PRESSURE; MIDDLE AGED; MUSCLE BIOPSY; MUSCLE REFLEX; MUSCLE SPINDLE; MUSCLE SYMPATHETIC NERVE ACTIVITY; SIGNAL TRANSDUCTION;

ADULT; BODY MASS INDEX; EXERCISE; FEMALE; GLYCOGEN PHOSPHORYLASE, MUSCLE FORM; GLYCOGEN STORAGE DISEASE TYPE V; HAND STRENGTH; HUMANS; MALE; MIDDLE AGED; MUSCLE, SKELETAL; REFERENCE VALUES; REFLEX; SYMPATHETIC NERVOUS SYSTEM;

EID: 0037936784     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2003.039347     Document Type: Review

References (40)

1. Alam M & Smirk RF (1937). Observations in man upon a blood pressure raising reflex arising from the voluntary muscles. J Physiol 89, 372-383.
2. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD & Julius D (1997). The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389, 816-824.
3. Conover WJ (1981). Rank transformations as a bridge between parametric and nonparametric statistics. Am Stat 35, 124-129.
4. Coote JH, Hilton SM & Perez-Gonzales JF (1971). The reflex nature of the pressor response to muscular exercise. J Physiol 215, 789-804.
5. Costa F & Biaggioni I (1994). Role of adenosine in the sympathetic activation produced by isometric exercise in humans. J Clin Invest 93, 1654-1660.
6. Ettinger S, Gray K, Whisler S & Sinoway L (1991). Dichloro-acetate reduces sympathetic nerve responses to static exercise. Am J Physiol 261, H1653-1658.
7. Gail M, Williams R, Byar DP & Brown C (1976). How many controls? J Chron Dis 29, 723-731.
8. + and lactate ions. J Physiol 500, 319-329.
9. + channel on ischemia-sensing neurons. Nat Neurosci 4, 869-870.
10. Lewis SF & Haller RG (1986). The pathophysiology of McArdle's disease: clues to regulation in exercise and fatigue. J Appl Physiol 61, 391-401.
11. Lingueglia E, de Weille JR, Bassilana F, Heurteaux C, Sakai H, Waldmann R & Lazdunski M (1997). A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells. J Biol Chem 272, 29778-29783.
12. Littrell RC, Milliken GA, Stroup WW & Wolfinger RD (1996). SAS System for Mixed Models. SAS Institute, Cary, NC, USA.
13. McCloskey DI & Mitchell JH (1972). Reflex cardiovascular and respiratory responses originating in exercising muscle. J Physiol 224, 173-186.
14. MacLean DA, Imadojemu VA & Sinoway LI (2000). Interstitial pH, K(+), lactate, and phosphate determined with MSNA during exercise in humans. Am J Physiol 278, R563-571.
15. MacLean DA, Vickery LM & Sinoway LI (2001). Elevated interstitial adenosine concentrations do not activate the muscle reflex. Am J Physiol 280, H546-553.
16. Mark AL, Victor RG, Nerhed C & Wallin BG (1985). Microneurographic studies of the mechanisms of sympathetic nerve responses to static exercise in humans. Circ Res 57, 461-469.
17. Mitchell JH (1990). J.B. Wolffe memorial lecture. Neural control of the circulation during exercise. Med Sci Sports Exerc 22, 141-154.
18. Mitchell JH, Kaufman MP & Iwamoto GA (1983). The exercise pressor reflex: its cardiovascular effects, afferent mechanisms, and central pathways. Annu Rev Physiol 45, 229-242.
19. Pan HL, Longhurst JC, Eisenach JC & Chen SR (1999). Role of protons in activation of cardiac sympathetic C-fibre afferents during ischaemia in cats. J Physiol 518, 857-66.
20. Pryor SL, Lewis SF, Haller RG, Bertocci LA & Victor RG (1990). Impairment of sympathetic activation during static exercise in patients with muscle phosphorylase deficiency (McArdle's disease). J Clin Invest 85, 1444-1449.
21. Rotto DM & Kaufman MP (1988). Effect of metabolic products of muscular contraction on discharge of group III and IV afferents. J Appl Physiol 64, 2306-2313.
22. + activity in cat hindlimb muscle. J Appl Physiol 67, 256-263.
23. Sheriff DD, Wyss CR, Rowell LB & Scher AM (1987). Does inadequate oxygen delivery trigger pressor response to muscle hypoperfusion during exercise? Am J Physiol 253, H1199-1207.
24. Sinoway L, Prophet S, Gorman I, Moser T, Schernberger J, Dolecki M, Briggs R & Zelis R (1989). Muscle acidosis during static exercise is associated with calf vasoconstriction. J Appl Physiol 66, 429-436.
25. Sinoway LI, Wroblewski KJ, Prophet SA, Ettinger SM, Gray KS, Whisler SK, Miller G & Moore RL (1992). Glycogen depletion-induced lactate reductions attenuate reflex responses in exercising humans. Am J Physiol 263, H1499-1505.
26. + derived from lactic acid and hypercapnia. Am J Physiol 262, H748-753.
27. Steen KH, Steen AE & Reeh PW (1995). A dominant role of acid pH in inflammatory excitation and sensitization of nociceptors in rat skin, in vitro. J Neurosci 15, 3982-3989.
28. Thimm F, Carvalho M, Babka M & Meier Zu Verl E (1984). Reflex increases in heart-rate induced by perfusing the hind leg of the rat with solutions containing lactic acid. Pflugers Arch 400, 286-293.
29. Ugawa S, Ueda T, Ishida Y, Nishigaki M, Shibata Y & Shimada S (2002). Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors. J Clin Invest 110, 1185-1190.
30. Vallbo AB, Hagbarth K-E, Torejbork H & Wallin B (1979). Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves. Physiol Rev 59, 919-957.
31. Victor RG, Bertocci LA, Pryor SL & Nunnally RL (1988). Sympathetic nerve discharge is coupled to muscle cell pH during exercise in humans. J Clin Invest 82, 1301-1305.
32. Victor RG, Leimbach WN, JR., Seals DR, Wallin BG & Mark AL (1987a). Effects of the cold pressor test on muscle sympathetic nerve activity in humans. Hypertension 9, 429-436.
33. Victor RG, Pryor SL, Secher NH & Mitchell JH (1989). Effects of partial neuromuscular blockade on sympathetic nerve responses to static exercise in humans. Circ Res 65, 468-476.
34. Victor RG, Seals DR & Mark AL (1987b). Differential control of heart rate and sympathetic nerve activity during dynamic exercise. Insight from intraneural recordings in humans. J Clin Invest 79, 508-516.
35. Victor RG, Secher NH, Lyson T & Mitchell JH (1995). Central command increases muscle sympathetic nerve activity during intense intermittent isometric exercise in humans. Circ Res 76, 127-131.
36. Vissing J, MacLean DA, Vissing SF, Sander M, Saltin B & Haller RG (2001). The exercise metaboreflex is maintained in the absence of muscle acidosis: insights from muscle microdialysis in humans with McArdle's disease. J Physiol 537, 641-649.
37. Vissing SF, Scherrer U & Victor RG (1991). Stimulation of skin sympathetic nerve discharge by central command. Differential control of sympathetic outflow to skin and skeletal muscle during static exercise. Circ Res 69, 228-238.
38. Vissing J, Vissing SF, MacLean DA, Saltin B, Quistorff B & Haller RG (1998). Sympathetic activation in exercise is not dependent on muscle acidosis. Direct evidence from studies in metabolic myopathies. J Clin Invest 101, 1654-1660.
39. + channel specific for sensory neurons. J Biol Chem 272, 20975-20978.
40. Waldmann R, Champigny G, Bassilana F, Heurteaux C & Lazdunski M (1997b). A proton-gated cation channel involved in acid-sensing. Nature 386, 173-177.