Role of protons in activation of cardiac sympathetic C-fibre afferents during ischaemia in cats

Journal of Physiology

Volumn 518, Issue 3, 1999, Pages 857-866

  Pan, Hui Lin ^a   Longhurst, John C ^b,c   Eisenach, James C ^a   Chen, Shao Rui ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUFFER; CARBON DIOXIDE; LACTATE SODIUM; LACTIC ACID; PHOSPHATE; PROTON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HEART INFARCTION; HEART INNERVATION; HEART MUSCLE ISCHEMIA; HEART NERVE; HYPERCAPNIA; MALE; NONHUMAN; PH; PRIORITY JOURNAL; SENSORY NERVE; ACID BASE BALANCE; ADRENERGIC SYSTEM; ADULT; CAT; CORONARY ARTERY; EPICARDIUM; IN VIVO STUDY; OXYGEN CONSUMPTION; SINGLE UNIT ACTIVITY;

EID: 0033178416     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1999.0857p.x     Document Type: Article

References (36)

1. ABE, T., MORGAN, D., SENGUPTA, J. N., GEBHART, G. F. & GUTTERMAN, D. D. (1998). Attenuation of ischemia-induced activation of cardiac sympathetic afferents following brief myocardial ischemia in cats. Journal of the Autonomic Nervous System 71, 28-36.
2. BAKER, D. G., COLERIDGE, H. M., COLERIDGE, J. C. G. & NERDRUM, T. (1980). Search for a cardiac nociceptor: stimulation by bradykinin of sympathetic afferent nerve endings in the heart of the cat. Journal of Physiology 306, 519-536.
3. BARBER, M. J., MUELLER, T. M., DAVIES, B. G. & ZIPES, D. P. (1984). Phenol topically applied to canine left ventricular epicardium interrupts sympathetic hut not vagal afferents. Circulation Research 55, 532-544.
4. BEVAN, S. & YEATS, J. (1989). Protons activate a cation conductance in a subpopulation of rat dorsal root ganglion neurons. Journal of Physiology 433, 145-161.
5. BOSNJAK, Z. J., ZUPERKU, E. J., COON, R. L. & KAMPINE, J. P. (1979). Acute coronary artery occlusion and cardiac sympathetic afferent nerve activity. Proceedings of Society for Experimental Biology & Medicine 161, 142-148.
6. BROWN, A. M. (1967). Excitation of afferent cardiac sympathetic nerve fibres during myocardial ischaemia. Journal of Physiology 190, 35-53.
7. CERVERO, F. (1994). Sensory innervation of the viscera: peripheral basis of visceral pain. Physiological Reviews 74, 95-138.
8. CHANDLER, M. J., GARRISON, D. W., BRENNAN, T. J. & FOREMAN, R. D. (1989). Effects of chemical and electrical stimulation of the midbrain on feline T2-T6 spinoreticular and spinal cell activity evoked by cardiopulmonary afferent input. Brain Research 496, 148-164.
9. CHANDLER, M. J., ZHANG, J. & FOREMAN, R. D. (1998) Cardio-pulmonary sympathetic input excites primate cuneothalamic neurons: comparison with spinothalamic tract neurons. Journal of Neurophysiology 80, 628-637.
10. GNECCHI-RUSCONE, T., MONTANO, N., CONTINI, M., GUAZZI, M., LOMBARDI, F. & MALLIANI, A. (1995). Adenosine activates cardiac sympathetic afferent fibers and potentiates the excitation induced by coronary occlusion. Journal of the Autonomic Nervous System 53, 175-184.
11. GUZMAN, F., BRAUN, C. & LIM, K. S. (1962). Visceral pain and the pseudoaffective response to intra-arterial injection of bradykinin and other analgesic agents. Archives Internationales de Pharmacodynamie et de Therapie 136, 353-384.
12. + and lactate ions. Journal of Physiology 500, 319-329.
13. 2 and hydroxyl radicals. American Journal of Physiology 269, H888-901.
14. KIMURA, E., HASHIMOTO, K., FURUKAWA, S. & HAYAKAWA, H. (1973). Changes in bradykinin level in coronary sinus blood after the experimental occlusion of a coronary artery. American Heart Journal 85, 635-647.
15. KUO, D., ORAVITZ, J. J. & DEGROAT, W. C. (1984). Tracing of afferent and efferent pathways in the left inferior cardiac nerve of the cat using retrograde and transganglionic transport of horseradish peroxidase. Brain Research 321, 111-118.
16. MALLIANI, A., SCHWARTZ, P. J. & ZANCHETTI, A. (1969). A sympathetic reflex elicited by experimental coronary occlusion. American Journal of Physiology 217, 703-709.
17. MOORE, R. M. & SINGLETON, A. O. (1935). A pseudaffective reflex evoked by injections into the left coronary artery and the peripheral paths of the pain fibers which are concerned. American Journal of Physiology 113, 99-100.
18. NISHI, K., SAKANASHI, M. & TAKENAKA, F. (1977). Activation of afferent cardiac sympathetic nerve fibers of the cat by pain producing substances and by noxious heat. Pflügers Archiv 372, 53-61.
19. OPIE, L. H., OWEN, P., THOMAS, M. & SAMSON, R. (1973). Coronary sinus lactic measurements in assessment of myocardial ischemia. American Journal of Cardiology 32, 295-305.
20. PAL, P., KOLEY, J., BHATTACHARYYA, S., GUPTA, J. S. & KOLEY, B. (1989). Cardiac nociceptors and ischemia: role of sympathetic afferents in cat. Japanese Journal of Physiology 39, 131-144.
21. PAN, H.-L. & LONGHURST, J. C. (1995). Lack of a role of adenosine in activation of ischemically sensitive cardiac sympathetic afferents. American Journal of Physiology 269, H106-113.
22. PETERSON, M. & LAMOTTE, R. H. (1993). Effect of protons on the inward current evoked by capsaicin in isolated dorsal root ganglion cells. Pain 54, 37-42.
23. POOLE-WILSON, P. A. (1978). Measurement of myocardial intracellular pH in pathological states. Journal of Molecular and Cellular Cardiology 10, 511-526.
24. RANG, H. P., BEVAN, S. & DRAY, A. (1991). Chemical activation of nociceptive peripheral neurons. British Medical Bulletin 47, 534-548.
25. SAKAI, K., ICHIHARA, K., NASA, Y., KAMIGAKI, M. & ABIKO, Y. (1990). Dichloroacetate attenuates myocardial acidosis and metabolic changes induced by partial occlusion of the coronary artery in dogs. Archives Internationales de Pharmacodynamie et de Therapie 307, 92-108.
26. SCHNEIDER, U., POOLE, R. C., HALESTRAP, A. P. & GRAFE, P. (1993). Lactate-proton co-transport and its contribution to interstitial acidification during hypoxia in isolated rat spinal roots. Neuroscience 4, 1153-1162.
27. + derived from lactic acid and hypercapnia. American Journal of Physiology 262, H748-753.
28. STEEN, K. H., REEH, P. W., ANTON, F. & HANDWERKER, H. O. (1992). Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro. Journal of Neuroscience 12, 86-95.
29. STEEN, K. H., STEEN, A. E. & REEH, P. W. (1995). A dominant role of acid pH in inflammatory excitation and sensitization of nociceptors in rat skin, in vitro. Journal of Neuroscience 15, 3982-3989.
30. THAMES, M. D., KINUGAWA, T. & DIBNER-DUNLAP, M. E. (1993) Reflex sympathoexcitation by cardiac sympathetic afferents during myocardial ischemia: role of adenosine. Circulation 87, 1698-1704.
31. 2 receptors in cats. Journal of Physiology 510, 633-641.
32. UCHIDA, Y. & MURAO, S. (1975). Acid-induced excitation of afferent cardiac sympathetic nerve fibers. American Journal of Physiology 228, 27-33.
33. VEELKEN, R., GLABASNIA, A., STETTER, A., HILGERS, K. F., MANN, J. F. & SCHMIEDER, R. E. (1996). Epicardial bradykinin B2 receptors elicit a sympathoexcitatory reflex in rats. Hypertension 28, 615-621.
34. WALDMANN, R., CHAMPIGNY, G., BASSILANA, F., HEURTEAUX, C. & LAZDUNSKI, M. (1997). A proton-gated cation channel involved in acid-sensing. Nature 386, 173-177.
35. WHITE, J. C. (1957). Cardiac pain: anatomic pathway and physiologic mechanisms. Circulation 16, 644-655.
36. YAN, G.-X. & KLEBER, A. (1992). Changes in extracellular and intra-cellular pH in ischemic rabbit papillary muscle. Circulation Research 71, 460-470.