Of mice and men, or: A pill for emphysema?

Respiration

Volumn 70, Issue 2, 2003, Pages 135-136

  Kummer, Friedrich ^a  

^a WILHELMINEN HOSPITAL   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; ELASTASE; ELASTIN; LEUKOCYTE ELASTASE INHIBITOR; MESSENGER RNA; RETINOIC ACID;

ANIMAL BEHAVIOR; CELL DIFFERENTIATION; CELL MATURATION; CYTOLOGY; DRUG TOLERABILITY; EDITORIAL; EMPHYSEMA; EXPERIMENTAL MODEL; GENE ACTIVATION; LUNG ALVEOLUS; LUNG ALVEOLUS WALL; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA;

ANIMALS; MICE; MICE, INBRED STRAINS; MODELS, ANIMAL; PULMONARY ALVEOLI; TRETINOIN;

EID: 0037908995     PISSN: 00257931     EISSN: None     Source Type: Journal    
DOI: 10.1159/000070058     Document Type: Editorial

References (7)

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2. Massaro GD, Massaro D: Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats. Nat Med 1997;3:675-677.
3. Massaro GD, Massaro D: Retinoic acid treatment partially rescues failed septation in rats and in mice. Am J Physiol Lung Cell Mol Physiol 2000;278:L955-L960.
4. Belloni PN, Garvin L ,Mao CP, Bailey-Healy I, Leaffer D: Effects of all-trans retinoic acid in promoting alveolar repair. Chest 2000;117:235S-241S.
5. Mao JT, Goldin JG, Dermand J, Ibrahim G, Brown MS, Emerick A, McNitt-Gray MF, Gjertson DW, Estrada F, Tashkin DP, Roth MD: A pilot study of all-trans-retinoic acid for the treatment of human emphysema. Am J Respir Crit Care Med 2002;165:718-723.
6. Kuraki T, Ishibashi M, Takayama M, Shiraishi M, Yoshida M: A novel oral neutrophil elastase inhibitor (ONO-6818) inhibits human neutrophil elastase-induced emphysema in rats. Am J Respir Crit Care Med 2002;166:496-500.
7. Wright JL, Farmer SG, Churg A: Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs. Am J Respir Crit Care Med 2002;166:954-960.