메뉴 건너뛰기




Volumn 6, Issue 5, 2003, Pages 458-463

Statins, super-statins and cholesterol absorption inhibitors

Author keywords

Cholesterol absorption; Ezetimibe; Lipoprotein; Rosuvastatin; Statin

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; ATORVASTATIN; BETA CAROTENE; EZETIMIBE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; PITAVASTATIN; PLACEBO; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN;

EID: 0037869355     PISSN: 13697056     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (8)

References (49)
  • 2
    • 0003657411 scopus 로고    scopus 로고
    • American Heart Association, Dallas, TX, USA
    • American Heart Association: 1998 Heart and Stroke Statistical Update. American Heart Association, Dallas, TX, USA (1998).
    • (1998) 1998 Heart and Stroke Statistical Update
  • 3
    • 0033596281 scopus 로고    scopus 로고
    • Effect of statins on risk of coronary heart disease: A meta-analysis of randomized controlled trials
    • note
    • LaRosa JC, He J, Vupputuri S: Effect of statins on risk of coronary heart disease: A meta-analysis of randomized controlled trials. J Am Med Assoc (1999) 282:2340-2346. Trials in which participants were randomized to statin or control treatment for at least four years, and clinical disease or death was the primary outcome were included in this meta-analysis (n = 5). It was concluded that statin-associated CHD risk reduction in women was similar to that of men, while that of the elderly was similar to the middle-aged.
    • (1999) J Am Med Assoc , vol.282 , pp. 2340-2346
    • LaRosa, J.C.1    He, J.2    Vupputuri, S.3
  • 4
    • 0033868274 scopus 로고    scopus 로고
    • Perspectives: Benefits of reducing low-density lipoprotein cholesterol concentrations to < 100 mg/dl
    • Schaefer EJ, Brousseau ME: Perspectives: Benefits of reducing low-density lipoprotein cholesterol concentrations to < 100 mg/dl. Prev Cardiol (2000) 3:136-139.
    • (2000) Prev Cardiol , vol.3 , pp. 136-139
    • Schaefer, E.J.1    Brousseau, M.E.2
  • 5
    • 0021677678 scopus 로고
    • Hypocholesterolemic effects of mevinolin in patients with heterozygous familial hypercholesterolemia
    • Illingworth DR, Sexton GJ: Hypocholesterolemic effects of mevinolin in patients with heterozygous familial hypercholesterolemia. J Clin Invest (1984) 74:1972-1978.
    • (1984) J Clin Invest , vol.74 , pp. 1972-1978
    • Illingworth, D.R.1    Sexton, G.J.2
  • 7
    • 0023009048 scopus 로고
    • Therapeutic response to lovastatin (mevinolin) in nonfamilial hypercholesterolemia: A multicenter study
    • The Lovastatin Study Group II: Therapeutic response to lovastatin (mevinolin) in nonfamilial hypercholesterolemia: A multicenter study. J Am Med Assoc (1986) 256:2829-2834.
    • (1986) J Am Med Assoc , vol.256 , pp. 2829-2834
  • 8
    • 0022348071 scopus 로고
    • Influence of mevinolin on metabolism of low density lipoproteins in primary moderate hypercholesterolemia
    • Grundy SM, Vega GL: Influence of mevinolin on metabolism of low density lipoproteins in primary moderate hypercholesterolemia. J Lipid Res (1985) 26:1464-1475.
    • (1985) J Lipid Res , vol.26 , pp. 1464-1475
    • Grundy, S.M.1    Vega, G.L.2
  • 9
    • 0025345666 scopus 로고
    • Lovastatin therapy reduces low density lipoprotein ApoB levels in subjects with combined hyperlipidemia by reducing the production of ApoB-containing lipoproteins: Implications for the pathophysiology of ApoB production
    • Ara Y, Ramakrishnan R, Ginsberg HN: Lovastatin therapy reduces low density lipoprotein ApoB levels in subjects with combined hyperlipidemia by reducing the production of ApoB-containing lipoproteins: Implications for the pathophysiology of ApoB production. J Lipid Res (1990) 31:567-582.
    • (1990) J Lipid Res , vol.31 , pp. 567-582
    • Ara, Y.1    Ramakrishnan, R.2    Ginsberg, H.N.3
  • 10
    • 0025237506 scopus 로고
    • The hypolipidemic effects of lovastatin and clofibrate alone and in combination in patients with type III hyperlipoproteinemia
    • Illingworth DR, O'Malley JP: The hypolipidemic effects of lovastatin and clofibrate alone and in combination in patients with type III hyperlipoproteinemia. Metabolism (1990) 39:403-409.
    • (1990) Metabolism , vol.39 , pp. 403-409
    • Illingworth, D.R.1    O'Malley, J.P.2
  • 11
    • 0023880277 scopus 로고
    • Lovastatin therapy in familial dysbetalipoproteinemia: Effects on kinetics of apolipoprotein B
    • Vega GL, East C, Grundy SM: Lovastatin therapy in familial dysbetalipoproteinemia: Effects on kinetics of apolipoprotein B. Atherosclerosis (1988) 70:131-143.
    • (1988) Atherosclerosis , vol.70 , pp. 131-143
    • Vega, G.L.1    East, C.2    Grundy, S.M.3
  • 15
    • 0027513563 scopus 로고
    • Design and baseline results of the Scandinavian Simvastatin Survival Study of patients with stable angina and/or previous myocardial infarction
    • Scandinavian Simvastatin Survival Study Group: Design and baseline results of the Scandinavian Simvastatin Survival Study of patients with stable angina and/or previous myocardial infarction. Am J Cardiol (1993) 71:393-400.
    • (1993) Am J Cardiol , vol.71 , pp. 393-400
  • 16
    • 0027987849 scopus 로고
    • Randomized trial of cholesterol lowering in 4444 patients with heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • note
    • Scandinavian Simvastatin Survival Study Group: Randomized trial of cholesterol lowering in 4444 patients with heart disease: The Scandinavian Simvastatin Survival Study (4S). Lancet (1994) 344:1383-1389. This is the first study to evaluate the effects of cholesterol-lowering with a statin (simvastatin) on morbidity and mortality in men and women with CHD.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 17
    • 0032554686 scopus 로고    scopus 로고
    • Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S)
    • note
    • Pedersen TR, Olsson AG, Faergeman O, Kjekshus J, Wedel H, Berg K, Wilhelmsen L, Haghfelt T, Thorgeirsson G, Pyorala K, Miettinen T et al: Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S). Circulation (1998) 97:1453-1460. This report revealed that the reduction in major coronary events observed within the treatment group of the 4S trial was highly correlated with on-treatment levels and changes from baseline in total and LDL cholesterol, indicating that the beneficial effect of simvastatin observed in this group of CHD patients was determined mainly by the magnitude of the change in LDL-C.
    • (1998) Circulation , vol.97 , pp. 1453-1460
    • Pedersen, T.R.1    Olsson, A.G.2    Faergeman, O.3    Kjekshus, J.4    Wedel, H.5    Berg, K.6    Wilhelmsen, L.7    Haghfelt, T.8    Thorgeirsson, G.9    Pyorala, K.10    Miettinen, T.11
  • 18
    • 0026350717 scopus 로고
    • Rationale and design of a secondary prevention trial of lowering normal plasma cholesterol levels after acute myocardial infarction: The Cholesterol and Recurrent Events trial (CARE)
    • Sacks FM, Pfeffer MA, Moye L, Brown LE, Hamm P, Cole TG, Hawkins CM, Braunwald E: Rationale and design of a secondary prevention trial of lowering normal plasma cholesterol levels after acute myocardial infarction: The Cholesterol and Recurrent Events trial (CARE). Am J Cardiol (1991) 68:1436-1446.
    • (1991) Am J Cardiol , vol.68 , pp. 1436-1446
    • Sacks, F.M.1    Pfeffer, M.A.2    Moye, L.3    Brown, L.E.4    Hamm, P.5    Cole, T.G.6    Hawkins, C.M.7    Braunwald, E.8
  • 20
    • 0032554688 scopus 로고    scopus 로고
    • Relationship between plasma LDL concentrations during treatment with pravastatin and recurrent coronary events in the Cholesterol and Recurrent Events trial
    • Sacks FM, Moye LA, Davis BR, Cole TG, Rouleau JL, Nash DT, Pfeffer MA, Braunwald E: Relationship between plasma LDL concentrations during treatment with pravastatin and recurrent coronary events in the Cholesterol and Recurrent Events trial. Circulation (1998) 97:1446-1452.
    • (1998) Circulation , vol.97 , pp. 1446-1452
    • Sacks, F.M.1    Moye, L.A.2    Davis, B.R.3    Cole, T.G.4    Rouleau, J.L.5    Nash, D.T.6    Pfeffer, M.A.7    Braunwald, E.8
  • 21
    • 0029074865 scopus 로고
    • Design features and baseline characteristics of the LIPID (Long-Term Intervention with Pravastatin in Ischaemic Disease) Study: A randomized trial in patients with previous acute myocardial infarction and/or unstable angina pectoris
    • The LIPID Study Group: Design features and baseline characteristics of the LIPID (Long-Term Intervention with Pravastatin in Ischaemic Disease) Study: A randomized trial in patients with previous acute myocardial infarction and/or unstable angina pectoris. Am J Cardiol (1995) 76:474-479.
    • (1995) Am J Cardiol , vol.76 , pp. 474-479
  • 22
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
    • The LIPID Study Group: Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med (1998) 339:1349-1357.
    • (1998) N Engl J Med , vol.339 , pp. 1349-1357
  • 23
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group: MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial. Lancet (2002) 360:7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 24
    • 0037031094 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group: MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: A randomised placebo-controlled trial. Lancet (2002) 360:23-33.
    • (2002) Lancet , vol.360 , pp. 23-33
  • 26
    • 0037164314 scopus 로고    scopus 로고
    • Pravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomised controlled trial
    • note
    • Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Cobbe SM, Ford I, Gaw A, Hyland M, Jukema JW, Kamper AM et al: Pravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomised controlled trial. Lancet (2002) 360:1623-1630. This was the first study to carefully explore the benefits of statin therapy in terms of CHD risk reduction in the elderly.
    • (2002) Lancet , vol.360 , pp. 1623-1630
    • Shepherd, J.1    Blauw, G.J.2    Murphy, M.B.3    Bollen, E.L.4    Buckley, B.M.5    Cobbe, S.M.6    Ford, I.7    Gaw, A.8    Hyland, M.9    Jukema, J.W.10    Kamper, A.M.11
  • 28
    • 0036786383 scopus 로고    scopus 로고
    • No effect of age or gender on the pharmacokinetics of rosuvastatin: A new HMG-CoA reductase inhibitor
    • Martin PD, Dane AL, Nwose OM, Schneck DW, Warwick MJ: No effect of age or gender on the pharmacokinetics of rosuvastatin: A new HMG-CoA reductase inhibitor. J Clin Pharmacol (2002) 42:1116-1121.
    • (2002) J Clin Pharmacol , vol.42 , pp. 1116-1121
    • Martin, P.D.1    Dane, A.L.2    Nwose, O.M.3    Schneck, D.W.4    Warwick, M.J.5
  • 29
    • 1242296077 scopus 로고    scopus 로고
    • Optimizing the pharmacology of statins: Characteristics of rosuvastatin
    • Chapman MJ, McTaggart F: Optimizing the pharmacology of statins: Characteristics of rosuvastatin. Atheroscler Suppl (2002) 2:33-36.
    • (2002) Atheroscler Suppl , vol.2 , pp. 33-36
    • Chapman, M.J.1    McTaggart, F.2
  • 30
    • 0035451307 scopus 로고    scopus 로고
    • Effect of rosuvastatin on low-density lipoprotein cholesterol in patients with hypercholesterolemia
    • note
    • Olsson AG, Pears J, McKellar J, Mizan J, Raza A: Effect of rosuvastatin on low-density lipoprotein cholesterol in patients with hypercholesterolemia. Am J Cardiol (2001) 88:504-508. The results of two dose-ranging studies with rosuvastatin were described in this report. Relative to placebo, rosuvastatin significantly reduced LDL-C concentrations in a dose-dependent manner in hypercholesterolemic patients.
    • (2001) Am J Cardiol , vol.88 , pp. 504-508
    • Olsson, A.G.1    Pears, J.2    McKellar, J.3    Mizan, J.4    Raza, A.5
  • 31
    • 0036915307 scopus 로고    scopus 로고
    • Effects of rosuvastatin and atorvastatin compared over 52 weeks of treatment in patients with hypercholesterolemia
    • note
    • Olsson AG, Istad H, Luurila O, Ose L, Stender S, Tuomilehto J, Wiklund O, Southworth H, Pears J, Wilpshaar JW: Effects of rosuvastatin and atorvastatin compared over 52 weeks of treatment in patients with hypercholesterolemia. Am Heart J (2002) 144:1044-1051. This study compared the effects of rosuvastatin and atorvastatin in reducing LDL-C and achieving LDL-C goals in patients with primary hypercholesterolemia.
    • (2002) Am Heart J , vol.144 , pp. 1044-1051
    • Olsson, A.G.1    Istad, H.2    Luurila, O.3    Ose, L.4    Stender, S.5    Tuomilehto, J.6    Wiklund, O.7    Southworth, H.8    Pears, J.9    Wilpshaar, J.W.10
  • 32
    • 0036467895 scopus 로고    scopus 로고
    • Comparison of effects on low-density lipoprotein cholesterol and high-density lipoprotein cholesterol with rosuvastatin versus atorvastatin in patients with type IIa or IIb hyper-cholesterolemia
    • Davidson M, Ma P, Stein EA, Gotto AM Jr, Raza A, Chitra R, Hutchinson H: Comparison of effects on low-density lipoprotein cholesterol and high-density lipoprotein cholesterol with rosuvastatin versus atorvastatin in patients with type IIa or IIb hyper-cholesterolemia. Am J Cardiol (2002) 89:268-275.
    • (2002) Am J Cardiol , vol.89 , pp. 268-275
    • Davidson, M.1    Ma, P.2    Stein, E.A.3    Gotto A.M., Jr.4    Raza, A.5    Chitra, R.6    Hutchinson, H.7
  • 33
    • 84992920491 scopus 로고    scopus 로고
    • Rosuvastatin demonstrates greater reduction of low-density lipoprotein cholesterol compared with pravastatin and simvastatin in hypercholesterolaemic patients: A randomized, double-blind study
    • Paoletti R, Fahmy M, Mahla G, Mizan J, Southworth H: Rosuvastatin demonstrates greater reduction of low-density lipoprotein cholesterol compared with pravastatin and simvastatin in hypercholesterolaemic patients: A randomized, double-blind study. J Cardiovasc Risk (2001) 8:383-390.
    • (2001) J Cardiovasc Risk , vol.8 , pp. 383-390
    • Paoletti, R.1    Fahmy, M.2    Mahla, G.3    Mizan, J.4    Southworth, H.5
  • 34
    • 0000474622 scopus 로고    scopus 로고
    • ZD4522 is superior to atorvastatin in the treatment of patients with heterozygous familial hypercholesterolemia
    • Stein E, Strutt KL, Miller E, Southworth H: ZD4522 is superior to atorvastatin in the treatment of patients with heterozygous familial hypercholesterolemia. J Am Coll Cardiol (2001) 37(Suppl A):292A.
    • (2001) J Am Coll Cardiol , vol.37 , Issue.SUPPL. A
    • Stein, E.1    Strutt, K.L.2    Miller, E.3    Southworth, H.4
  • 35
    • 0002522668 scopus 로고    scopus 로고
    • Rosuvastatin (20, 40 and 80 mg) reduces LDL-C, raises HDL-C and achieves treatment goals more effectively than atorvastatin (20, 40 and 80 mg) in patients with heterozygous familial hypercholesterolemia
    • Stein E, Strutt KL, Miller E, Southworth H: Rosuvastatin (20, 40 and 80 mg) reduces LDL-C, raises HDL-C and achieves treatment goals more effectively than atorvastatin (20, 40 and 80 mg) in patients with heterozygous familial hypercholesterolemia. Atherosclerosis (2001) 2:90-91.
    • (2001) Atherosclerosis , vol.2 , pp. 90-91
    • Stein, E.1    Strutt, K.L.2    Miller, E.3    Southworth, H.4
  • 36
    • 0036234655 scopus 로고    scopus 로고
    • A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia
    • note
    • Saito Y, Yamada N, Teramoto T, Itakura H, Hata Y, Nakaya N, Mabuchi H, Tushima M, Sasaki J, Ogawa N, Goto Y: A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia. Atherosclerosis (2002) 162:373-379. In this multicenter, phase II trial conducted in Japan, pitavastatin lowered LDL-C by 38% in hyperlipidemic patients.
    • (2002) Atherosclerosis , vol.162 , pp. 373-379
    • Saito, Y.1    Yamada, N.2    Teramoto, T.3    Itakura, H.4    Hata, Y.5    Nakaya, N.6    Mabuchi, H.7    Tushima, M.8    Sasaki, J.9    Ogawa, N.10    Goto, Y.11
  • 38
    • 0030848734 scopus 로고    scopus 로고
    • In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of active metabolites of SCH48461
    • Van Heek M, France CF, Compton DS, McLeod RL, Yumibe NP, Alton KB, Sybertz EJ, Davis HR Jr: In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of active metabolites of SCH48461. J Pharmacol Exp Ther (1997) 283:157-163.
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 157-163
    • Van Heek, M.1    France, C.F.2    Compton, D.S.3    McLeod, R.L.4    Yumibe, N.P.5    Alton, K.B.6    Sybertz, E.J.7    Davis H.R., Jr.8
  • 39
    • 0032510318 scopus 로고    scopus 로고
    • Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4-hydroxyp henyl)-2-azetidinone (SCH 58235): A designed, potent, orally active inhibitor of cholesterol absorption
    • Rosenblum SB, Huynh T, Afonso A, Davis HR Jr, Yumibe N, Clader JW, Burnett DA: Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4-hydroxyp henyl)-2-azetidinone (SCH 58235): A designed, potent, orally active inhibitor of cholesterol absorption. J Med Chem (1998) 41:973-980.
    • (1998) J Med Chem , vol.41 , pp. 973-980
    • Rosenblum, S.B.1    Huynh, T.2    Afonso, A.3    Davis H.R., Jr.4    Yumibe, N.5    Clader, J.W.6    Burnett, D.A.7
  • 40
    • 0034003105 scopus 로고    scopus 로고
    • Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663
    • Van Heek M, Farley C, Compton DS, Hoos L, Alton KB, Sybertz EJ, Davis HR Jr: Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663. Br J Pharmacol (2000) 129:1748-1754.
    • (2000) Br J Pharmacol , vol.129 , pp. 1748-1754
    • Van Heek, M.1    Farley, C.2    Compton, D.S.3    Hoos, L.4    Alton, K.B.5    Sybertz, E.J.6    Davis H.R., Jr.7
  • 41
    • 0035831089 scopus 로고    scopus 로고
    • The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys
    • Van Heek M, Compton DS, Davis HR: The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys. Eur J Pharmacol (2001) 415:79-84.
    • (2001) Eur J Pharmacol , vol.415 , pp. 79-84
    • Van Heek, M.1    Compton, D.S.2    Davis, H.R.3
  • 42
    • 0034765624 scopus 로고    scopus 로고
    • The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl Coenzyme A reductase inhibitors in dogs
    • Davis HR Jr, Pula KK, Alton KB, Burrier RE, Watkins RW: The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl Coenzyme A reductase inhibitors in dogs. Metabolism (2001) 50:1234-1241.
    • (2001) Metabolism , vol.50 , pp. 1234-1241
    • Davis H.R., Jr.1    Pula, K.K.2    Alton, K.B.3    Burrier, R.E.4    Watkins, R.W.5
  • 43
    • 0000282451 scopus 로고    scopus 로고
    • The cholesterol absorption inhibitor ezetimibe (SCH58235) and lovastatin synergistically lower plasma cholesterol and inhibit the development of atherosclerosis
    • Davis HR Jr, Watkins RW, Compton DS, Cook JA, Hoos L, Pula K, Van Heek M: The cholesterol absorption inhibitor ezetimibe (SCH58235) and lovastatin synergistically lower plasma cholesterol and inhibit the development of atherosclerosis. J Am Coll Cardiol (2000) 35(Suppl 2A):252A.
    • (2000) J Am Coll Cardiol , vol.35 , Issue.SUPPL. 2A
    • Davis H.R., Jr.1    Watkins, R.W.2    Compton, D.S.3    Cook, J.A.4    Hoos, L.5    Pula, K.6    Van Heek, M.7
  • 44
    • 17944380533 scopus 로고    scopus 로고
    • Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: Pooled analysis of two phase II studies
    • note
    • Bays HE, Moore PB, Drehobl MA, Rosenblatt S, Toth PD, Dujovne CA, Knopp RH, Lipka LJ, LeBeaut AP, Yang B, Mellers LE: Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: Pooled analysis of two phase II studies. Clin Ther (2001) 23:1209-1230. The results of a multicenter, placebo-controlled, randomized trial, which examined the effects of ezetimibe on plasma lipoproteins in patients with primary hypercholesterolemia, are reported.
    • (2001) Clin Ther , vol.23 , pp. 1209-1230
    • Bays, H.E.1    Moore, P.B.2    Drehobl, M.A.3    Rosenblatt, S.4    Toth, P.D.5    Dujovne, C.A.6    Knopp, R.H.7    Lipka, L.J.8    LeBeaut, A.P.9    Yang, B.10    Mellers, L.E.11
  • 46
    • 0037111924 scopus 로고    scopus 로고
    • Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia
    • Dujovne CA, Ettinger MP, McNeer JF, Lipka LJ, LeBeaut AP, Suresh R, Yang B, Veltri EP: Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia. Am J Cardiol (2002) 90:1092-1097.
    • (2002) Am J Cardiol , vol.90 , pp. 1092-1097
    • Dujovne, C.A.1    Ettinger, M.P.2    McNeer, J.F.3    Lipka, L.J.4    Lebeaut, A.P.5    Suresh, R.6    Yang, B.7    Veltri, E.P.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.