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Rosenblum SB, Huynh T, Afonso A, Davis HR Jr, Yumibe N, Clader JW, Burnett DA: Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4-hydroxyp henyl)-2-azetidinone (SCH 58235): A designed, potent, orally active inhibitor of cholesterol absorption. J Med Chem (1998) 41:973-980.
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Yumibe, N.5
Clader, J.W.6
Burnett, D.A.7
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40
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Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663
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Van Heek M, Farley C, Compton DS, Hoos L, Alton KB, Sybertz EJ, Davis HR Jr: Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663. Br J Pharmacol (2000) 129:1748-1754.
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Van Heek, M.1
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Hoos, L.4
Alton, K.B.5
Sybertz, E.J.6
Davis H.R., Jr.7
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41
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The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys
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Van Heek M, Compton DS, Davis HR: The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys. Eur J Pharmacol (2001) 415:79-84.
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Van Heek, M.1
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Davis, H.R.3
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0034765624
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The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl Coenzyme A reductase inhibitors in dogs
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Davis HR Jr, Pula KK, Alton KB, Burrier RE, Watkins RW: The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl Coenzyme A reductase inhibitors in dogs. Metabolism (2001) 50:1234-1241.
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The cholesterol absorption inhibitor ezetimibe (SCH58235) and lovastatin synergistically lower plasma cholesterol and inhibit the development of atherosclerosis
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Davis HR Jr, Watkins RW, Compton DS, Cook JA, Hoos L, Pula K, Van Heek M: The cholesterol absorption inhibitor ezetimibe (SCH58235) and lovastatin synergistically lower plasma cholesterol and inhibit the development of atherosclerosis. J Am Coll Cardiol (2000) 35(Suppl 2A):252A.
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Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: Pooled analysis of two phase II studies
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note
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Bays HE, Moore PB, Drehobl MA, Rosenblatt S, Toth PD, Dujovne CA, Knopp RH, Lipka LJ, LeBeaut AP, Yang B, Mellers LE: Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: Pooled analysis of two phase II studies. Clin Ther (2001) 23:1209-1230. The results of a multicenter, placebo-controlled, randomized trial, which examined the effects of ezetimibe on plasma lipoproteins in patients with primary hypercholesterolemia, are reported.
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Lipka, L.J.8
LeBeaut, A.P.9
Yang, B.10
Mellers, L.E.11
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The plasma concentration and LDL-C relationship in patients receiving ezetimibe
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Ezzet F, Wexler D, Statkevich P, Kosoglou T, Patrick J, Lipka L, Mellars L, Veltri E, Batra V: The plasma concentration and LDL-C relationship in patients receiving ezetimibe. J Clin Pharmacol (2001) 41:943-949.
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Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia
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Dujovne CA, Ettinger MP, McNeer JF, Lipka LJ, LeBeaut AP, Suresh R, Yang B, Veltri EP: Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia. Am J Cardiol (2002) 90:1092-1097.
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Pharmacodynamic interaction between the selective cholesterol absorption inhibitor ezetimibe and lovastatin
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Kosoglou T, Meyer I, Cutler DL, Musiol B, Yang B, Zhu Y, Maxwell SE, Affrime MB, Veltri EP: Pharmacodynamic interaction between the selective cholesterol absorption inhibitor ezetimibe and lovastatin. Third International Conference on Coronary Artery Disease - From Prevention to Intervention, Lyon, France (2000).
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Pharmacodynamic interaction between the new selective cholesterol absorption inhibitor ezetimibe and atorvastatin
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Kosoglou T, Seiberling M, Statkevich P, Cutlre DL, Yang B, Anderson L, Maxwell SE, Affrime MB: Pharmacodynamic interaction between the new selective cholesterol absorption inhibitor ezetimibe and atorvastatin. J Am Coll Cardiol (2001) 37:229A.
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Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia
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Davidson MH, McGarry T, Bettis R, Melani L, Lipka LJ, LeBeaut AP, Suresh R, Sun S, Veltri EP: Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia. J Am Coll Cardiol (2002) 40:2125-2134.
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Davidson, M.H.1
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LeBeaut, A.P.6
Suresh, R.7
Sun, S.8
Veltri, E.P.9
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