Free radical induced increase in protein carbonyl is attenuated by low dose of adenosine in hippocampus and mid brain: Implication in neurodegenerative disorders

General Physiology and Biophysics

Volumn 22, Issue 1, 2003, Pages 29-39

  Parihar, Mordhwaj Singh ^a   Pandit, M K ^a  

^a VIKRAM UNIVERSITY   (India)

Author keywords

Adenosine; Alzheimer's disease; Free radical; Hippocampus; Mid brain; Neurodegeneration

Indexed keywords

ADENOSINE; ALPHA TOCOPHEROL; ASCORBIC ACID; CARBONYL DERIVATIVE; FREE RADICAL; GLUTATHIONE; TERT BUTYL HYDROPEROXIDE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOSE RESPONSE; EVIDENCE BASED MEDICINE; HIPPOCAMPUS; LOW DRUG DOSE; MALE; MESENCEPHALON; MOUSE; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PARKINSON DISEASE;

ADENOSINE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICALS; GLUTATHIONE; HIPPOCAMPUS; MALE; MESENCEPHALON; MICE; NEURODEGENERATIVE DISEASES; NEURONS; PROTEINS; TERT-BUTYLHYDROPEROXIDE;

ANIMALIA;

EID: 0037866562     PISSN: 02315882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Adams J. D., Klaidman L. K., Odunze I. N. (1989): Oxidative effects of MPTP in the midbrain. Res. Commun. Subst. Abuse. 10, 169-180
2. Adams J. D., Wang B., Klaidman L. K., Lebel C. P., Odunze I. N., Shah D. (1993): Aspects of brain oxidative stress induced by tert-butyl hydroperoxide. Free Radical Biol. Med. 15, 195-202
3. Aksenov M. Y., Aksenov M. V., Butterfield D. A., Geddes J. W., Markesbery W. R. (2001): Protein oxidation in the brian in Alzheimer's disease. Neuroscience (Oxford) 163, 373-383
4. Aksenov M. Y., Markesbery W. R. (2001): Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease. Neurosci. Lett. 302, 141-145
5. Bano S., Parihar M. S. (1997): Reduction of lipid peroxidation in different brain regions by a combination of α-tocopherol and ascorbic acid. J. Neural Transm., Suppl. 104, 1277-1286
6. 2 receptors. Neuroscience (Oxford) 94, 59-70
7. Beal M. F. (1997): Oxidative damage in neurodegenerative diseases. J. Neurosci. 3, 21-27
8. Bowling A. C., Schulz J. B., Brown R. H. Jr., Beal M. F. (1993): Superoxide dismutase activity, oxidative damage and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J. Neurochem. 61, 2322-2325
9. Calvin H. I., Medvedovsky C., Worgul B. W. (1986): Near-total glutathione depletion and age specific cataracts induced buthionine by sulfoximine in mice. Science (Washington, D. C.) 233, 553-555
10. 2+: effect of coenzyme Q redox state. Free Radical Biol. Med. 18, 55-59
11. Chavko M., Harabin A. L. (1996): Regional lipid peroxidation and protein oxidation in rat brain after hyperberic oxygen exposure. Free Radical Biol. Med. 20, 973-978
12. Clemense J. A. (2000): Cerebral ischemia: Gene activation, neuronal injury and the protective role of antioxidants. Free Radical Biol. Med. 28, 1526-1531
13. Cronstein B. N., Levine R. I., Belanoff J. (1986): Adenosine an endogenous inhibitor of neutrophil - mediated injury to endothelial cells. J. Clin. Invest. 78, 760-770
14. Culmsee C., Bondada, S., Mattson M. P. (2001): Hippocampus neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity. Mol. Brain Res. 87, 257-262
15. Davies K. J., Goldberg A. L. (1987): Proteins damaged in extracts of red blood cells. J. Biol. Chem. 262, 8220-8226
16. Dexter D. T., Sian J., Lees A. J., (1994): Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann. Neurol. 36, 348-355
17. Dubey A., Froster M. J., Lal H., Sohal R. S. (1996): Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of the mouse. Arch. Biochem. 333, 189-197
18. Evans P., Lyras L., Halliwell B. (1999): Measurement of protein carbonyls in human brain tissue. In: Methods in Enzymology (Ed. L. Packer), Vol. 300, pp. 145-166, Academic Press, USA
19. Floor E., Wetzel M. G. (1998): Increased protein oxidation in human substantia nigra pars compacta in comparison with basal ganglia and prefrontal cortex measured with an improved Dinitrophenyl hydrazene method assay. J. Neurochem. 70, 268-275
20. Gunther G. R., Herring M. B. (1991): Inhibition of neutrophil superoxide production by adenosine released from vascular endothelial cells. Ann. Vasc. Surg. 5, 325-330
21. Hall E.D., Andrus P.K., Althaus J.S. (1993): Hydroxyl radical production and lipid per-oxidation parallels selective post-ischemic vulnerability in gerbil brain. J. Neurosci. Res. 34, 107-112
22. Hall E. D. (1997): Degenerative and regenerative events in the central and peripheral nervous systems. In: Comprehensive Toxicology (Eds. I. G. Sipes, C. A. McQueen and A. J. Gandolfi) 11, pp. 41-58, Pregmon Press UK
23. Hemnani T., Parihar M. S. (1999): An attempt to bypass the bionergetic defects and oxidative stress in tert-butyl hydroperoxide induced neurotoxicity by pretreatment with a combinations of compounds in mice: implications in neurodegenerative disorders. In: Free Radicals and Antioxidants (Eds. P. P. Singh, A. K. Pendse, B. S. Bomb, M. K. Barjatiya and R. Ghosh), pp. 199-205, Chaudhary offset pvt. Ltd. Udaipur, India
24. Hu H. L., Forsey R. J., Blades T. J., Barratt M. E., Parmar P., Powell J. R. (2001): Antioxidants may contribute in the fight against ageing: an in vitro model. Mech. Ageing Dev. 121, 217-230
25. Jollow D. J., Mitchell J. R., Zampaglione N., Gillete J. R. (1974): Bromobenzene-induced liver necrosis, Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology 11, 151-169
26. Levine R. L., Garland D., Oliver C. N., Amici A., Climent I., Lenz A. G., Ahn B. W., Shaltiel S., Stadtman E. R. (1990): Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol. 186, 464-478
27. Lowry O. H., Rosenberg N. J., Farr A. L., Randal R. J. (1994): Protein measurement with the Folin-Phenol reagent. J. Biol Chem. 193, 265-275
28. Maggiwar S., Dhanraj D. N., Somani S. M. Ramkumar V. (1994): Adenosine act as an endogenous activator of the cellular antioxidant defense system. Biochem. Biophys. Res. Commun. 201, 508-515
29. Markesbery W. R. (1997): Oxidative stress hypothesis in Alzhemier's disease. Free Radical Biol. Med. 23, 134-147
30. Meister A. (1983): Selective modification of glutatione metabolism. Science 220, 472-477
31. Meister A. (1983): Metabolism and function of glutathione. In: Glutathione; Chemical, Biochemical and Medical Aspects (Eds. D. Dolphin, R. Poulson and O. Avramovic), Vol. 3, Part A, pp. 367-389, John Willey and Sons, New York
32. Mentzer R. M. Jr., Lasley R. B. (1997): Adensine and myocardial protection in humans. In: Adenosine, Cardioprosection and its Clinical Aplication (Eds. R. M. Mentzer, M. Kitakaze, J. M. Downey and M. Hori), pp. 167-175, Kluwer Academic Publisher, Boston, Dordrecht, London
33. Oliver C. N., Fulks R., Levine R. L., Fucci L., Rivett. A. J., Roseman J. E., Stadtman E. R. (1984): Molecular Biology of Aging (Eds. A. K. Roy and B. Chaterjee), pp. 235-262, Academic Press, New York
34. Oliver C. N., Ahn B. W., Moerman E. J., Goldstein S., Stadtman E. R. (1987): Age-related changes in oxidized proteins. J. Biol. Chem. 262, 5488-5491
35. Parihar M. S., Manjula Y., Bano S., Hemnani T., Javeri T., Prakash P. (1997): Nicotinamide and α-tocopherol combination partially protects t-butyl hydroperoxide-induced neurotoxicity: implications for neurodegenerative disease. Curr. Sci. 73, 290-293
36. Perry G., Raina A. K., Nunomura A., Wataya T., Sayre L. M., Smith M. A. (2000): How important is oxidative damage? Lessons from Alzheimer's disease. Free Radical Biol. Med. 28, 831-834
37. Regan R. F., Guo Y. (2001): Magnesium deprivation decreases cellular reduced glutathione and causes oxidative neuronal death in murine cortical cultures. Brain Res. 890, 177-183
38. Rivett A. J., Levine R. L. (1990): Metal-catalyzed oxidation of Escherichia coli glutamine synthetase: correlation of structural and functional changes. Arch. Biochem. Biophys. 278, 26-34
39. Roghani M., Behzadi G. (2001): Neuroprotective effect of vitamin E on the early model of Parkinson's disease in rat: behavioral and histochemical evidence. Brain Res. 892, 211-217
40. Rush G. F., Gorski J. R., Ripple M. G., Sowinski J., Bugleski P., Hewitti W. R. (1985): Organic hydroperoxide-induced lipid peroxidation and cell death in isolated hepatocytes. Toxicol. Appl. Pharmacol. 78, 473-483
41. Sian J., Dexter D. T., Lees A. J. (1994): Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann. Neurol. 36, 348-355
42. Smith M. A., Rortkamp C. A., Nunomura A., Raina A. K., Perry G. (2000): Oxidative stress in Alzheimer's disease. Biochim. Biophys. Acta. 1502, 139-144
43. Sofic E., Lange K. W., Jellinger K. (1992): Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease. Neurosci. Lett. 142, 128-130
44. Stadtman E. (1992): Protein oxidation and aging. Science (Washington, D. C.) 257, 1220-1244
45. Stadtman E. R., Oliver C. N. (1991). Metal catalyzed oxidation of proteins: physiological consequences. Biochemistry 226, 7728-7732
46. Suzuki W. A., Clayton N. S. (2000): The hippocampus and memory: a comparative and ethological perspective. Curr. Opin. Neurobiol. 10, 768-773
47. Sweeney M. I. (1996): Adenosine release and uptake in cerebellar granule neurons both occur via an equilibrative nucleoside carrier that is modulated by G proteins. J. Neurochem. 67, 81-88
48. Tirmenstein M. A., Nicholls-Grzemski F. A., Zhang J. G., Fariss M. W. (2000): Glutathione depletion and the production of reactive oxygen species in isolated hepatocyte suspensions. Chem. Biol. Interact. 127, 201-217
49. Vitolo O. V., Giotti M. T., Galli C., Borsello T., Calissano P. (1998): Adenosine and ADP prevent apoptosis in cultured rat cerebellar granule cells. Brain Res. 809, 297-301