Periodic abstinence enhances nociception without significantly altering the antinociceptive efficacy of spinal morphine in the rat

Neuroscience Letters

Volumn 344, Issue 3, 2003, Pages 145-148

  Dunbar, Stuart A ^a   Karamian, Ivan G ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Naloxone; Nociception; Opioid; Spinal; Tolerance; Withdrawal

Indexed keywords

GLUTAMIC ACID; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NALOXONE;

AMINO ACID SYNTHESIS; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG TOLERANCE; DRUG WITHDRAWAL; HYPERALGESIA; MALE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR SENSITIVITY;

EID: 0037865268     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(03)00227-1     Document Type: Article

References (25)

1. Basbaum A.I. Insights into the development of opioid tolerance. Pain. 61:1995;349-352.
2. Bharagava H.N. The effects of naltrexone on the development of physical dependence on morphine. Eur. J. Pharmacol. 50:1978;193-202.
3. Collingdridge G.L., Bliss T.V.P. NMDA receptors; their role in long-term potentiation. Trends Neurosci. 10:1987;288-294.
4. Crain S.M., Crain B., Peterson E.R., Simon E.J. Development of tolerance to opiates and opioid peptides in organotypic cultures of mouse spinal cord. Life Sci. 25:1979;1797-1802.
5. Crain S.M., Shen K.F. Chronic morphine-treated sensory ganglion neurons remain supersensitive to the excitatory effects of naloxone for months after return to normal culture medium: an in vitro model of protracted opioid dependence. Brain Res. 694:1995;103-110.
6. Davis A.M., Inturrisi C.E. D-Methadone blocks morphine tolerance and N-methyl-D-aspartate-induced hyperalgesia. J. Pharmacol. Exp. Ther. 289:1999;1048-1053.
7. Doverty M., White J.M., Somogyi A.A., Bochner F., Ali R., Ling W. Hyperalgesic responses in methadone maintenance patients. Pain. 90:2001;91-96.
8. Dunbar S.A., Pulai I.J. Repetitive opioid abstinence causes progressive hyperalgesia sensitive to NMDA receptor blockade in the rat. J. Pharmacol. Exp. Ther. 284:1998;678-686.
9. Dunbar S.A., Yaksh T.L. Concurrent spinal infusion of MK801 blocks spinal tolerance and dependence induced by chronic intrathecal morphine in the rat. Anesthesiology. 84:1996;1177-1188.
10. Elliott K., Minami N., Kolesnikov Y.A., Pasternak G.W., Inturrisi C.E. The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphine but not to kappa opioids. Pain. 56:1994;69-75.
11. Feng J., Kendig J.J. N-Methyl-D-aspartate receptors are implicated in hyperresponsiveness following naloxone reversal of alfentanil in isolated rat spinal cord. Neurosci. Lett. 189:1995;128-130.
12. Galbraith J.A., Mrosko B., Myers R.R. A system to measure thermal nociception. J. Neurosci. Methods. 49:1993;63-68.
13. Gold L.H., Stinus L., Inturrisi C.E., Koob G.F. Prolonged tolerance, dependence and abstinence following subcutaneous morphine pellet implantation in the rat. Eur. J. Pharmacol. 253:1994;45-51.
14. Goldstein A., Aranow L., Kalman S.M. Principles of Drug Action. 2nd Edition:1974;Wiley, New York.
15. Ibuki T., Dunbar S.A., Yaksh T.L. Effect of transient naloxone antagonism on tolerance development in rats receiving continuous spinal morphine infusion. Pain. 70:1997;125-132.
16. Jhamandas K.H., Marsala M., Ibuki T., Yaksh T.L. Spinal amino acid release and precipitated withdrawal in rats chronically infused with spinal morphine. J. Neurosci. 16:1996;2758-2766.
17. Laulin J.P., Celerier E., Larcher A., Le Moal M., Simonnet G. Opiate tolerance to daily heroin administration: an apparent phenomenon associated with enhanced pain sensitivity. Neuroscience. 89:1999;631-636.
18. Lutfy K., Shen K.Z., Kwon I.S., Cai S.X., Woodward R.M., Keana J.F., Weber E. Blockade of morphine tolerance by ACEA-1328, a novel NMDA receptor/glycine site antagonist. Eur. J. Pharmacol. 273:1995;187-189.
19. Plummer J.L., Cmielewski P.L., Tallents S., Hall P.D., Odontiadis J., Gourlay G.K., Owen H. Development of tolerance to antinociceptive effects of an intrathecal morphine/clonidine combination in rats. Naunyn-Schmiedeberg's Arch. Pharmacol. 351:1995;618-623.
20. Powell K.J., Hosokawa A., Bell A., Sutak M., Milne B., Quirion R., Jhamandas K. Comparative effects of cyclo-oxygenase and nitric oxide synthase inhibition on the development and reversal of spinal opioid tolerance. Br. J. Pharmacol. 127:1999;631-644.
21. Tallurida R.J., Murray R.B. Manual of Pharmacologic Calculations and Computer Programs. 1981;Springer-Verlag, New York.
22. Tao P.L., Hwang C.L., Chen C.Y. U-50,488 blocks the development of morphine tolerance and dependence at a very low dose in guinea pigs. Eur. J. Pharmacol. 256:1994;281-286.
23. Trujillo K.A., Akil H. Inhibition of morphine tolerance and dependence by the NMDA receptor antagonist MK-801. Science. 251:1991;85-87.
24. Zharkovsky A., Katajamaki J., Seppala T., Ahtee L. Morphine-induced analgesia in rats withdrawn from concurrent nimodipine and morphine treatment. Pain. 79:1999;217-222.
25. Zhou H., Ge X., Wang L.Z., Ma L., Pei G. Attenuation of morphine tolerance and dependence in scopolamine-treated rats. NeuroReport. 10:1999;2007-2010.