Synthesis of new conformationally constrained pentasaccharides as molecular probes to investigate the biological activity of heparin

Biochimie

Volumn 85, Issue 1-2, 2003, Pages 91-99

  Sisu, Eugen ^b,c   Tripathy, Sasmita ^b,d   Mallet, Jean M ^b   Driguez, Pierre A ^a   Hérault, Jean P ^a   Sizun, Philippe ^a   Herbert, Jean M ^a   Petitou, Maurice ^a   Sinay, Pierre ^b  

^a SANOFI   (France)

^b ECOLE NORMALE SUPÉRIEURE   (France)

^c Institutul de Chimie   (Romania)

^d INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

Antithrombin; Conformation; Factor Xa; Heparin; Sulfate

Indexed keywords

ANTITHROMBIN; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 10A INHIBITOR; HEPARIN; IDURONIC ACID; PENTASACCHARIDE; SULFATE;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DRUG ACETYLATION; DRUG ACTIVITY; DRUG SYNTHESIS; HUMAN; MOLECULAR PROBE; PROTEIN INTERACTION; PROTEIN METHYLATION; STRUCTURE ANALYSIS; SULFATION; THROMBOCYTE ACTIVATION;

ANTITHROMBIN III; ANTITHROMBINS; BINDING SITES; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; GLYCOPROTEINS; HEPARIN; IDURONIC ACID; MOLECULAR PROBES; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFATES;

EID: 0037837504     PISSN: 03009084     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-9084(03)00054-3     Document Type: Article

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