메뉴 건너뛰기




Volumn 468, Issue 3, 2003, Pages 191-198

Involvement of spinal tyrosine kinase in inflammatory and N-methyl-D-aspartate-induced hyperalgesia in rats

Author keywords

Antinociception; Inflammatory hyperalgesia; NMDA receptor; Spinal cord; Tyrosine kinase inhibitor

Indexed keywords

ANALGESIC AGENT; ANTINOCICEPTIVE AGENT; CARRAGEENAN; CYCLODEXTRIN; DIZOCILPINE; KAOLIN; LAVENDUSTIN A; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; THIAMYLAL;

EID: 0037837359     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(03)01718-7     Document Type: Article
Times cited : (17)

References (45)
  • 1
    • 0025286174 scopus 로고
    • Excitatory amino acid receptors and nociceptive neurotransmission in rat spinal cord
    • Aanonsen L.M., Lei S., Wilcox G.L. Excitatory amino acid receptors and nociceptive neurotransmission in rat spinal cord. Pain. 41:1990;309-321.
    • (1990) Pain , vol.41 , pp. 309-321
    • Aanonsen, L.M.1    Lei, S.2    Wilcox, G.L.3
  • 2
    • 0028830731 scopus 로고
    • Nerve growth factor amplifies cyclic AMP production in the HT4 neuronal cell line
    • Berg K.A., Maayani S., McKay R., Clarke W.P. Nerve growth factor amplifies cyclic AMP production in the HT4 neuronal cell line. J. Neurochem. 64:1995;220-228.
    • (1995) J. Neurochem. , vol.64 , pp. 220-228
    • Berg, K.A.1    Maayani, S.2    McKay, R.3    Clarke, W.P.4
  • 3
    • 0021215525 scopus 로고
    • The behavioural effects of an N-methyl aspartate receptor antagonist following application to the lumbar spinal cord of conscious rats
    • Cahusac P.M., Evans R.H., Hill R.G., Rodriquez R.E., Smith D.A. The behavioural effects of an N-methyl aspartate receptor antagonist following application to the lumbar spinal cord of conscious rats. Neuropharmacology. 23:1984;719-724.
    • (1984) Neuropharmacology , vol.23 , pp. 719-724
    • Cahusac, P.M.1    Evans, R.H.2    Hill, R.G.3    Rodriquez, R.E.4    Smith, D.A.5
  • 4
    • 0028840931 scopus 로고
    • Tyrosine kinase activity is essential for interleukin-1 beta-stimulated production of interleukin-6 in U373 human astrocytoma cells
    • Carlson R.O., Aschmies S.H. Tyrosine kinase activity is essential for interleukin-1 beta-stimulated production of interleukin-6 in U373 human astrocytoma cells. J. Neurochem. 65:1995;2491-2499.
    • (1995) J. Neurochem. , vol.65 , pp. 2491-2499
    • Carlson, R.O.1    Aschmies, S.H.2
  • 5
    • 0030933616 scopus 로고    scopus 로고
    • Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat
    • Chaplan S.R., Malmberg A.B., Yaksh T.L. Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. J. Pharmacol. Exp. Ther. 280:1997;829-838.
    • (1997) J. Pharmacol. Exp. Ther. , vol.280 , pp. 829-838
    • Chaplan, S.R.1    Malmberg, A.B.2    Yaksh, T.L.3
  • 6
    • 0034487286 scopus 로고    scopus 로고
    • Secondary heat, but not mechanical, hyperalgesia induced by subcutaneous injection of bee venom in the conscious rat: Effect of systemic MK-801, a non-competitive NMDA receptor antagonist
    • Chen H.S., Chen J. Secondary heat, but not mechanical, hyperalgesia induced by subcutaneous injection of bee venom in the conscious rat: effect of systemic MK-801, a non-competitive NMDA receptor antagonist. Eur. J. Pain. 4:2000;389-401.
    • (2000) Eur. J. Pain , vol.4 , pp. 389-401
    • Chen, H.S.1    Chen, J.2
  • 7
    • 0025999839 scopus 로고
    • Central neural mediation of secondary hyperalgesia following heat injury in rats: Neuropeptides and excitatory amino acids
    • Coderre T.J., Melzack R. Central neural mediation of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids. Neurosci. Lett. 131:1991;71-74.
    • (1991) Neurosci. Lett. , vol.131 , pp. 71-74
    • Coderre, T.J.1    Melzack, R.2
  • 8
    • 0027295722 scopus 로고
    • Nerve growth factor stimulates the production of inositol 1,3,4- and 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate in PC12 cells
    • Contreras M.L. Nerve growth factor stimulates the production of inositol 1,3,4- and 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate in PC12 cells. J. Neurochem. 61:1993;1035-1042.
    • (1993) J. Neurochem. , vol.61 , pp. 1035-1042
    • Contreras, M.L.1
  • 9
    • 0026008423 scopus 로고
    • Antagonism at the glycine site on the NMDA receptor reduces spinal nociception in the rat
    • Dickenson A.H., Aydar E. Antagonism at the glycine site on the NMDA receptor reduces spinal nociception in the rat. Neurosci. Lett. 121:1991;263-266.
    • (1991) Neurosci. Lett. , vol.121 , pp. 263-266
    • Dickenson, A.H.1    Aydar, E.2
  • 10
    • 0035826949 scopus 로고    scopus 로고
    • NMDA receptor subunits are phosphorylated by activation of neurotrophin receptors in PSD of rat spinal cord
    • Di Luca M., Gardoni F., Finardi A., Pagliardini S., Cattabeni F., Battaglia G., Missale C. NMDA receptor subunits are phosphorylated by activation of neurotrophin receptors in PSD of rat spinal cord. NeuroReport. 8(12):2001;1301-1305.
    • (2001) NeuroReport , vol.8 , Issue.12 , pp. 1301-1305
    • Di Luca, M.1    Gardoni, F.2    Finardi, A.3    Pagliardini, S.4    Cattabeni, F.5    Battaglia, G.6    Missale, C.7
  • 11
    • 0033601984 scopus 로고    scopus 로고
    • N-methyl D-aspartate induced mechanical allodynia is blocked by nitric oxide synthase and cyclooxygenase-2 inhibitors
    • Dolan S., Nolan A.M. N-methyl D-aspartate induced mechanical allodynia is blocked by nitric oxide synthase and cyclooxygenase-2 inhibitors. NeuroReport. 10:1999;449-452.
    • (1999) NeuroReport , vol.10 , pp. 449-452
    • Dolan, S.1    Nolan, A.M.2
  • 12
    • 0032429305 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus
    • Frerking M., Malenka R.C., Nicoll R.A. Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus. J. Neurophysiol. 80:1998;3383-3386.
    • (1998) J. Neurophysiol. , vol.80 , pp. 3383-3386
    • Frerking, M.1    Malenka, R.C.2    Nicoll, R.A.3
  • 13
    • 0037101627 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia
    • Guo W., Zou S., Guan Y., Ikeda T., Tal M., Dubner R., Ren K. Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia. J. Neurosci. 22:2002;6208-6217.
    • (2002) J. Neurosci. , vol.22 , pp. 6208-6217
    • Guo, W.1    Zou, S.2    Guan, Y.3    Ikeda, T.4    Tal, M.5    Dubner, R.6    Ren, K.7
  • 14
    • 0033232536 scopus 로고    scopus 로고
    • Excitatory synaptogenesis between identified Lymnaea neurons requires extrinsic trophic factors and is mediated by receptor tyrosine kinases
    • Hamakawa T., Woodin M.A., Bjorgum M.C., Painter S.D., Takasaki M., Lukowiak K., Nagle G.T., Syed N.I. Excitatory synaptogenesis between identified Lymnaea neurons requires extrinsic trophic factors and is mediated by receptor tyrosine kinases. J. Neurosci. 19:1999;9306-9312.
    • (1999) J. Neurosci. , vol.19 , pp. 9306-9312
    • Hamakawa, T.1    Woodin, M.A.2    Bjorgum, M.C.3    Painter, S.D.4    Takasaki, M.5    Lukowiak, K.6    Nagle, G.T.7    Syed, N.I.8
  • 15
    • 0035029467 scopus 로고    scopus 로고
    • Small-dose S(+)-ketamine reduces postoperative pain when applied with ropivacaine in epidural anesthesia for total knee arthroplasty
    • Himmelseher S., Ziegler-Pithamitsis D., Argiriadou H., Martin J., Jelen-Esselborn S., Kochs E. Small-dose S(+)-ketamine reduces postoperative pain when applied with ropivacaine in epidural anesthesia for total knee arthroplasty. Anesth. Analg. 92:2001;1290-1295.
    • (2001) Anesth. Analg. , vol.92 , pp. 1290-1295
    • Himmelseher, S.1    Ziegler-Pithamitsis, D.2    Argiriadou, H.3    Martin, J.4    Jelen-Esselborn, S.5    Kochs, E.6
  • 16
    • 0023922799 scopus 로고
    • Protein tyrosine kinase activity and its endogenous substrates in rat brain: A subcellular and regional survey
    • Hirano A.A., Greengard P., Huganir R.L. Protein tyrosine kinase activity and its endogenous substrates in rat brain: a subcellular and regional survey. J. Neurochem. 50:1988;1447-1455.
    • (1988) J. Neurochem. , vol.50 , pp. 1447-1455
    • Hirano, A.A.1    Greengard, P.2    Huganir, R.L.3
  • 17
    • 0028988240 scopus 로고
    • Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus
    • Kang H., Schuman E.M. Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science. 267:1995;1658-1662.
    • (1995) Science , vol.267 , pp. 1658-1662
    • Kang, H.1    Schuman, E.M.2
  • 18
    • 0033821162 scopus 로고    scopus 로고
    • Effects of intrathecal ketamine added to bupivacaine for spinal anaesthesia
    • Kathirvel S., Sadhasivam S., Saxena A., Kannan T.R., Ganjoo P. Effects of intrathecal ketamine added to bupivacaine for spinal anaesthesia. Anaesthesia. 55:2000;899-904.
    • (2000) Anaesthesia , vol.55 , pp. 899-904
    • Kathirvel, S.1    Sadhasivam, S.2    Saxena, A.3    Kannan, T.R.4    Ganjoo, P.5
  • 20
    • 0031762250 scopus 로고    scopus 로고
    • Involvement of Ras/MAP kinase in the regulation of Ca2+ channels in adult bullfrog sympathetic neurons by nerve growth factor
    • Lei S., Dryden W.F., Smith P.A. Involvement of Ras/MAP kinase in the regulation of Ca2+ channels in adult bullfrog sympathetic neurons by nerve growth factor. J. Neurophysiol. 80:1998;1352-1361.
    • (1998) J. Neurophysiol. , vol.80 , pp. 1352-1361
    • Lei, S.1    Dryden, W.F.2    Smith, P.A.3
  • 22
    • 0032543995 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity
    • Levine E.S., Crozier R.A., Black I.B., Plummer M.R. Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity. Proc. Natl. Acad. Sci. U. S. A. 95:1998;10235-10239.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 10235-10239
    • Levine, E.S.1    Crozier, R.A.2    Black, I.B.3    Plummer, M.R.4
  • 23
    • 0032579763 scopus 로고    scopus 로고
    • BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities
    • Lin S.Y., Wu K., Levine E.S., Mount H.T.J., Suen P.C., Black I.B. BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities. Mol. Brain Res. 55:1998;20-27.
    • (1998) Mol. Brain Res. , vol.55 , pp. 20-27
    • Lin, S.Y.1    Wu, K.2    Levine, E.S.3    Mount, H.T.J.4    Suen, P.C.5    Black, I.B.6
  • 24
  • 25
    • 0030782407 scopus 로고    scopus 로고
    • Nerve growth factor- and neurotrophin-3-induced changes in nociceptive threshold and the release of substance P from the rat isolated spinal cord
    • Malcangio M., Garrett N.E., Gruwys S., Tomlinson D.R. Nerve growth factor- and neurotrophin-3-induced changes in nociceptive threshold and the release of substance P from the rat isolated spinal cord. J. Neurosci. 17:1997;8459-8467.
    • (1997) J. Neurosci. , vol.17 , pp. 8459-8467
    • Malcangio, M.1    Garrett, N.E.2    Gruwys, S.3    Tomlinson, D.R.4
  • 28
    • 0030050543 scopus 로고    scopus 로고
    • Acute thermal hyperalgesia in the rat is produced by activation of N-methyl-D-aspartate receptors and protein kinase C and production of nitric oxide
    • Meller S.T., Dykstra C., Gebhart G.F. Acute thermal hyperalgesia in the rat is produced by activation of N-methyl-D-aspartate receptors and protein kinase C and production of nitric oxide. Neuroscience. 71:1996;327-335.
    • (1996) Neuroscience , vol.71 , pp. 327-335
    • Meller, S.T.1    Dykstra, C.2    Gebhart, G.F.3
  • 29
    • 0030776204 scopus 로고    scopus 로고
    • Nerve growth factor treatment increases brain-derived neurotrophic selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord
    • Michael G.J., Averill S., Nitkunan A., Rattray M., Bennett D.L.H., Yan Q., Priestley J.V. Nerve growth factor treatment increases brain-derived neurotrophic selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord. J. Neurosci. 17:1997;8476-8490.
    • (1997) J. Neurosci. , vol.17 , pp. 8476-8490
    • Michael, G.J.1    Averill, S.2    Nitkunan, A.3    Rattray, M.4    Bennett, D.L.H.5    Yan, Q.6    Priestley, J.V.7
  • 30
    • 0023183240 scopus 로고
    • A model of chronic pain in the rat: High-resolution neuroanatomical approach identifies alterations in multiple opioid systems in the periaqueductal grey
    • Millan M.J., Morris B.J., Colpaert F.C., Herz A. A model of chronic pain in the rat: high-resolution neuroanatomical approach identifies alterations in multiple opioid systems in the periaqueductal grey. Brain Res. 28(416):1987;349-353.
    • (1987) Brain Res. , vol.28 , Issue.416 , pp. 349-353
    • Millan, M.J.1    Morris, B.J.2    Colpaert, F.C.3    Herz, A.4
  • 31
    • 0024947837 scopus 로고
    • Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus
    • Onoda T., Iinuma H., Sasaki Y., Hamada M., Isshiki K., Naganawa H., Takeuchi T. Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus. J. Nat. Prod. 52:1989;1252-1257.
    • (1989) J. Nat. Prod. , vol.52 , pp. 1252-1257
    • Onoda, T.1    Iinuma, H.2    Sasaki, Y.3    Hamada, M.4    Isshiki, K.5    Naganawa, H.6    Takeuchi, T.7
  • 32
    • 0026709480 scopus 로고
    • The effects of a non-competitive NMDA antagonist MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation
    • Ren K., Hylden J.L.K., Williams G.M., Ruda M.A., Dubner R. The effects of a non-competitive NMDA antagonist MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation. Pain. 50:1992;331-344.
    • (1992) Pain , vol.50 , pp. 331-344
    • Ren, K.1    Hylden, J.L.K.2    Williams, G.M.3    Ruda, M.A.4    Dubner, R.5
  • 33
    • 0038496408 scopus 로고    scopus 로고
    • Effects of intrathecally administered Trk inhibitor (K-252a) on carrageenan-induced mechanical allodynia in rats
    • Sato E., Takano Y., Sato I. Effects of intrathecally administered Trk inhibitor (K-252a) on carrageenan-induced mechanical allodynia in rats. 10th World Congress on Pain Abs. 2002;P60.
    • (2002) 10th World Congress on Pain Abs , pp. 60
    • Sato, E.1    Takano, Y.2    Sato, I.3
  • 34
    • 0032055877 scopus 로고    scopus 로고
    • Tackling pain at the source. New ideas about nociceptors
    • Snider W.D., McMahon S.B. Tackling pain at the source. New ideas about nociceptors. Neuron. 20:1998;629-632.
    • (1998) Neuron , vol.20 , pp. 629-632
    • Snider, W.D.1    McMahon, S.B.2
  • 35
    • 0034894905 scopus 로고    scopus 로고
    • Evaluation of the safety and efficacy of epidural ketamine combined with morphine for postoperative analgesia after major upper abdominal surgery
    • Subramaniam K., Subramaniam B., Pawar D.K., Kumar L. Evaluation of the safety and efficacy of epidural ketamine combined with morphine for postoperative analgesia after major upper abdominal surgery. J. Clin. Anesth. 13:2001;339-344.
    • (2001) J. Clin. Anesth. , vol.13 , pp. 339-344
    • Subramaniam, K.1    Subramaniam, B.2    Pawar, D.K.3    Kumar, L.4
  • 36
    • 0033582266 scopus 로고    scopus 로고
    • PSD-95 promotes fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A
    • Tezuka T., Umemori H., Akiyama T., Nakanishi S., Yamamoto T. PSD-95 promotes fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A. Proc. Natl. Acad. Sci. U. S. A. 96:1999;435-440.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 435-440
    • Tezuka, T.1    Umemori, H.2    Akiyama, T.3    Nakanishi, S.4    Yamamoto, T.5
  • 37
    • 0032898266 scopus 로고    scopus 로고
    • Involvement of excitatory amino acid receptors and nitric oxide in the rostral ventromedial medulla in modulating secondary hyperalgesia produced by mustard oil
    • Urban M.O., Coutinho S.V., Gebhart G.F. Involvement of excitatory amino acid receptors and nitric oxide in the rostral ventromedial medulla in modulating secondary hyperalgesia produced by mustard oil. Pain. 81:1999;45-55.
    • (1999) Pain , vol.81 , pp. 45-55
    • Urban, M.O.1    Coutinho, S.V.2    Gebhart, G.F.3
  • 38
    • 0026167912 scopus 로고
    • Protein tyrosine kinases and phosphatases in the nervous system
    • Wagner K.R., Mei L., Huganir R.L. Protein tyrosine kinases and phosphatases in the nervous system. Curr. Opin. Neurobiol. 1:1991;65-73.
    • (1991) Curr. Opin. Neurobiol. , vol.1 , pp. 65-73
    • Wagner, K.R.1    Mei, L.2    Huganir, R.L.3
  • 39
    • 0028360327 scopus 로고
    • Regulation of NMDA receptors by tyrosine kinases and phosphatases
    • Wang Y.T., Salter M.W. Regulation of NMDA receptors by tyrosine kinases and phosphatases. Nature. 369:1994;233-235.
    • (1994) Nature , vol.369 , pp. 233-235
    • Wang, Y.T.1    Salter, M.W.2
  • 40
    • 0025974775 scopus 로고
    • The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; Implications for the treatment of post-injury pain hypersensitivity states
    • Woolf C.J., Thompson S.W. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states. Pain. 44:1991;293-299.
    • (1991) Pain , vol.44 , pp. 293-299
    • Woolf, C.J.1    Thompson, S.W.2
  • 41
    • 0037184685 scopus 로고    scopus 로고
    • Involvement of a spinal brain-derived neurotrophic factor/full-length TrkB pathway in the development of nerve injury-induced thermal hyperalgesia in mice
    • Yajima Y., Narita M., Narita M., Matsumoto N., Suzuki T. Involvement of a spinal brain-derived neurotrophic factor/full-length TrkB pathway in the development of nerve injury-induced thermal hyperalgesia in mice. Brain Res. 958:2002;338-346.
    • (2002) Brain Res. , vol.958 , pp. 338-346
    • Yajima, Y.1    Narita, M.2    Narita, M.3    Matsumoto, N.4    Suzuki, T.5
  • 42
    • 0027507420 scopus 로고
    • The effects of morphine, MK-801, an NMDA antagonist, and CP-96,345, an NK1 antagonist, on the hyperesthesia evoked by carrageenan injection in the rat paw
    • Yamamoto T., Shimoyama N., Mizuguchi T. The effects of morphine, MK-801, an NMDA antagonist, and CP-96,345, an NK1 antagonist, on the hyperesthesia evoked by carrageenan injection in the rat paw. Anesthesiology. 78:1993;124-133.
    • (1993) Anesthesiology , vol.78 , pp. 124-133
    • Yamamoto, T.1    Shimoyama, N.2    Mizuguchi, T.3
  • 43
    • 0029891545 scopus 로고    scopus 로고
    • Intrathecal ketamine reduces morphine requirements in patients with terminal cancer pain
    • Yang C.Y., Wong C.S., Chang J.Y., Ho S.T. Intrathecal ketamine reduces morphine requirements in patients with terminal cancer pain. Can. J. Anaesth. 43:1996;379-383.
    • (1996) Can. J. Anaesth. , vol.43 , pp. 379-383
    • Yang, C.Y.1    Wong, C.S.2    Chang, J.Y.3    Ho, S.T.4
  • 44
    • 0030273264 scopus 로고    scopus 로고
    • Characterization of time course of spinal amino acids, citrulline and PGE2 release after carrageenan/kaolin-induced knee joint inflammation: A chronic microdialysis study
    • Yang L.C., Marsala M., Yaksh T.L. Characterization of time course of spinal amino acids, citrulline and PGE2 release after carrageenan/kaolin-induced knee joint inflammation: a chronic microdialysis study. Pain. 67:1996;345-354.
    • (1996) Pain , vol.67 , pp. 345-354
    • Yang, L.C.1    Marsala, M.2    Yaksh, T.L.3
  • 45
    • 0031053363 scopus 로고    scopus 로고
    • NMDA channel regulation by channel-associated protein tyrosine kinase Src
    • Yu X.M., Askalan R., Keil G.J., Salter M.W. NMDA channel regulation by channel-associated protein tyrosine kinase Src. Science. 275:1997;674-678.
    • (1997) Science , vol.275 , pp. 674-678
    • Yu, X.M.1    Askalan, R.2    Keil, G.J.3    Salter, M.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.