An update on ascorbic acid in poultry

World's Poultry Science Journal

Volumn 59, Issue 2, 2003, Pages 161-184+260+263+266+270

  Whitehead, C C ^a   Keller, T ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b BASF SE   (Germany)

Author keywords

Antioxidant; Ascorbic acid; Behaviour; Bone; Immunity; Stress

Indexed keywords

AVES;

EID: 0037810928     PISSN: 00439339     EISSN: None     Source Type: Journal    
DOI: 10.1079/WPS20030010     Document Type: Conference Paper

References (135)

1. ABD-ELLAH, A.M. (1995) Effect of ascorbic acid supplementation on performance of laying hens during hot summer months. Assiut Veterinary Medicine Journal 34: 83-95.
2. ABDEL-MAKSOUD, A.M. (1999) Influence of ascorbic acid supplementation on some hormonal and haematological responses in Japanese quail exposed to acute heat stress. Egyptian Journal of Nutrition and Feeds 2: 729-742.
3. ABOU-EL-ELLA, M.A. and ISMAIL, A.M. (1999) Ascorbic acid, sodium bicarbonate and ammonium chloride supplementation in broiler diets at high environmental temperature. Egyptian Journal of Nutrition and Feeds 2: 581-591.
4. ABOU-ZEID, A.E., MOHAMED, F.F. and EL-SOUD, S.B.A. (1999) Impact of vitamin C and/or zinc supplementation on performance and immunity of broilers. Egyptian Poultry Science Journal 19: 635-655.
5. AHMAD, M.M., MORENG, R.E. and MULLER, H.D. (1967) Breed responses in body temperature to elevated environmental temperature and ascorbic acid. Poultry Science 46: 6.
6. AL-TAWEIL, R.N. and KASSAB, A. (1990) Effect of dietary vitamin C on ascites in broiler chicks. International Journal for Vitamin and Nutrition Research 60: 366-371.
7. ANDREASEN, C.B. and FRANK, D.E. (1999) The effects of ascorbic acid on in vitro heterophil function. Avian Diseases 43: 656-663.
8. ATTIA, M. and EL-SOKKARY A. (1976) Effect of different levels of vitamin C on body temperature of White Russian birds during heat stress. Egyptian Veterinary Medical Journal 26: 65.
9. AYDEMIR, T., OZTURK, R., BOZKAYA, L.A. and TARHAN, L. (2000) Effects of antioxidant vitamins A, C, E and trace elements Cu, Se on CuZnSOD, GSH-Px, CAT and LPO levels in chicken erythrocytes. Cell Biochemistry and Function 18: 109-115.
10. BALNAVE, D. (1993) Influence of saline drinking water on eggshell quality and formation. World's Poultry Science Journal 49: 109-119.
11. BALNAVE, D. and MUHEEREZA, S.K. (1997) Improving eggshell quality at high temperatures with dietary sodium bicarbonate. Poultry Science 76: 588-593.
12. BALNAVE, D. and ZHANG, D. (1992) Responses in eggshell quality from dietary ascorbic acid supplementation of hens receiving saline drinking water. Australian Journal of Agricultural Research 43: 1259-1264.
13. BALNAVE, D. and YOSELEWITZ, I. (1987) The relation between sodium chloride concentration in drinking water and eggshell damage. British Journal of Nutrition 58: 503-509.
14. BALNAVE, D., ZHANG, D. and MOREN, R.E. (1991) Use of ascorbic acid to prevent the decline in eggshell quality observed with saline drinking water. Poultry Science 70: 848-852.
15. BARAK-SHALOM, T., SCHICKLER, M., KNOPOV, V., SHAPIRA, R., HURWITZ, S. and PINES, M. (1995) Synthesis and phosphorylation of osteopontin by avian epiphyseal growth plate chondrocytes as affected by differentiation. Comparative Biochemistry and Physiology. C, Pharmacology, Toxicology and Endocrinology 111: 49-59.
16. BASHIR, I.N., MUNIR, M.A., SAEED, M.A., RAZ, A. AND RAZA, F.K. (1998) Immunomodulatory effects of water soluble vitamins on heat stressed broiler chickens. Indian Journal of Animal Nutrition 15: 11-17.
17. BEHL, C.R., KADUSKAR, M.R., THATTE, V.R. and KHIRE, D.W. (1995) Influence of dietary calcium and ascorbic acid supplementation on the performance of caged laying hens during hot weather. Indian Veterinary Journal 72: 586-590.
18. BELL, D.E. and MARION, J.E. (1990) Vitamin C in laying hen diets. Poultry Science 69: 1900-1904.
19. BENABDELJELIL, K., RYADI, A. and JENSEN, L.S. (1990) Effect of dietary ascorbic acid supplementation on the performance of brown-egg laying hens and egg quality. Animal Feed Science and Technology 30: 301-311.
20. BLAHA, J., DRASLAROVA, J. and KROESNA, K. (2000) The effect of vitamin and electrolyte supplements on broiler performance under heat stress. Agricultura Tropica et Subtropica 33: 52-58.
21. BLALOCK, J.E. and SMITH, E.M. (1985) A complete regulatory loop between the immune and neuroendocrine systems. Federation Proceedings 44: 108-111.
22. BOTTJE, W.G. and WIDEMAN, R.F. (1995) Potential role of free radicals in the pathogenesis of pulmonary hypertension syndrome. Poultry and Avian Biology Reviews 6: 221-231.
23. BOTTJE, W.G., WANG, S., BEERS, K.W. and CAWTHON, D. (1998) Lung lining fluid antioxidants in male broilers: age-related changes under thermoneutral and cold temperature conditions. Poultry Science 77: 1905-1912.
24. BOU, R., GUARDIOLA, F., GRAU, A., GRIMPA, S., MANICH, A., BARROETA, A. and CODONY, R. (2001) Influence of dietary fat source, alpha-tocopherol and ascorbic acid supplementation on sensory quality of dark chicken meat. Poultry Science 80: 800-807.
25. CAMPO, J.L. and CARNICER, C. (1994) Effects of several 'stressors' on tonic immobility reaction of chickens. Archiv für Geflügelkunde 58: 75-78.
26. CHENG, T.K., COON, C.N. and HAMRE, M.L. (1990) Effect of environmental stress on the ascorbic acid requirement of laying hens. Poultry Science 69: 774-780.
27. CIER, D., RIMSKY, Y., RAND, N., POLISHUK, O., GUR, N., SHOSHAN, A.B., FRISH, Y., MOSHE, A.B., BEN SHOSHAN, A. and BEN MOSHE, A. (1992) The effects of supplementing ascorbic acid on broilers performance under summer conditions. Proceedings of World's Poultry Congress, Amsterdam, 1: 586-589.
28. CIER, D., RIMSKY, Y., RAND, N., POLISHUK, O., GUR, N., SHOSHAN, A.B, MOSHE, A.B., BEN SHOSHAN, A. and BEN MOSHE, A. (1992) The effects of supplementing breeders feeds with ascorbic acid on the performance of their broiler offsprings. Proceedings of World's Poultry Congress, Amsterdam, 1: 620-621.
29. CREEL, L.H., MAURICE, D.V., LIGHTSEY, S.F. and GRIMES, L.W. (2001) Stability of dietary ascorbic acid and effect of supplementation on reproductive performance of broiler breeder chickens. British Poultry Science 42: 96-101.
30. CRISTE, R.D., TARANU, I., SERDARU, M., BURLACA, G. and BURLACA, R. (1996) Addition of 1500 ppm ascorbic acid and the possibility of reducing the level of supplemental iron in the diets of broilers raised at temperatures specific to the summer season in Romania. Archiva Zootechnica 4: 21-33.
31. DE FARIA, D.E., JUNQUEIRA, O.M., SOUZA, P.A. and TITTO, E.A.L. (2001). Performance, body temperature and egg quality of laying hens fed vitamins D and C under three environmental temperatures. Brasilian Journal of Poultry Science 3: 49-56.
32. DOAN, B.H. (2000) Effects of different levels of dietary calcium and supplemental vitamin C on growth, survivability, leg abnormalities, total ash in the tibia, serum calcium and phosphorus in 0-4 week old chicks under tropical conditions. Livestock Research for Rural Development 12: 1-4.
33. DOAN, B.H. and GIANG, V.D. (1998) Effects of vitamin C supplementation of a diet for 0-4 week old chicks on the absorption of calcium and phosphorus. Agricultura Tropica et Subtropica 31: 117-121.
34. EDWARDS, H.M. Jr (1989) Effect of vitamin C, environmental temperature, chlortetracycline, and vitamin D on the development of tibial dyschondroplasia in chickens. Poultry Science 68: 1527-1534.
35. EDWARDS, H.M. Jr and VELTMANN, J.R. Jr (1983) The role of calcium and phosphorus in the etiology of tibial dyschondroplasia in young chicks. Journal of Nutrition 113: 1568-1575.
36. EL-FIKY, A.A. (1998) Addition of ascorbic acid to relieve the adverse effects of using underground and saline water on egg quality and some physiological parameters. Egyptian Poultry Science Journal 18: 81-101.
37. EL-GENDI, G.M., IRAQI, M.M. and ELRAHMAN, A.A.A. (1999) Effect of vitamin C supplementation on some productive and physiological parameters in laying hens. Egyptian Journal of Nutrition and Feeds 2: 649-664.
38. ELMOTY, A.K., HAMDY, A.M.M. and EL-LATIF, S.A.A. (1999) Some productive and metabolic changes of growing Japanese quail as affected by vitamin C administration under cold stress. Egyptian Journal of Nutrition and Feeds 2: 695-701.
39. EL-ZANATY, K. (1994) Effect of ascorbic acid on broiler chicks infected with infectious bursal disease virus. Assiut Veterinary Medical Journal 31: 334-344.
40. FARQUHARSON, C. and WHITEHEAD, C.C. (1995) Differentiation and mineralization in chick chondrocytes maintained in a high cell density culture: a model for endochondral ossification. In Vitro Cell Development Biology 31: 288-294.
41. FARQUHARSON, C., BERRY, J.L., MAWER, E.B., SEAWRIGHT, E. and WHITEHEAD, C.C. (1998) Ascorbic acid-induced chondrocyte differentiation: the role of the extracellular matrix and 1,25-dihydroxycholecalciferol. European Journal of Cell Biology 76: 110-118.
42. FARR, A.J., SALMAN, H.K., KRAUTMANN, B.A., GONZALES, L. and MACDONALD, A. (1988) Effect of high level of vitamin C dosage at 32 hours prior to slaughter on processing parameters of broiler chickens. Poultry Science 67 (suppl. 1): 85 (abstr).
43. FLEMING, R.H., MCCORMACK, H.A. and WHITEHEAD, C.C. (1998) Bone structure and strength at different ages in laying hens and effects of dietary particulate limestone, vitamin K and ascorbic acid. British Poultry Science 39: 434-440.
44. FLETCHER, D.L. and CASON, J.A. (1991) Influence of ascorbic acid on broiler shrink and processing yields. Poultry Science 70: 2191-2196.
45. FRANCHINI, A., BERGONZONI, M.L., MELOTTI, C. and MINELLI, G. (2001) The effects of dietary supplementation with high doses of vitamin E and C on the quality traits of chicken semen. Archiv für Geflügelkunde 65: 76-81.
46. FRANCHINI, A., BERTUZZI, S., TOSARELLI, C., IANELLI, S., NANNI COSTA, A. and STEFONI, S. (1994) Chronobiological influence of vitamin C on chicken immune functions. Archiv für Gefiügelkunde 58: 165-175.
47. FRANCHINI, A., MELUZZI, A., MANFREDA, G. and TOSARELLI, C. (1994) Vitamin C and bone tissue in broiler. Archiv für Geflügelkunde 54: 161-165.
48. FRATZER, F.H., ALMQUIST, H.J. and VOHRA, P. (1996) Effect of diet on growth and plasma ascorbic acid in chicks. Poultry Science 75: 82-89.
49. FRY, S.C. (1998) Oxidative scission of plant cell wall polysaccharides by ascorbic-induced free radicals. Biochemical Journal 332: 507-515.
50. GECHA, O.M. and FAGAN, J.M. (1992) Protective effect of ascorbic acid on the breakdown of proteins exposed to hydrogen peroxide in chicken skeletal muscle. Journal of Nutrition 12: 2087-2093.
51. GOTO, K., HARRIS, G.C. and WALDROUP, P.W. (1979) Relationship between pimpling in eggshells, environmental temperature and carbonic anhydrase activity of certain body tissues. Poultry Science 58: 1014.
52. GRANOT, I., BARTOV, I., PLAVNIK, I., WAX, E., HURWITZ., S. and PINES, M. (1991) Increased skin tearing in broilers and reduced collagen synthesis in skin in vivo and in vitro in response to the coccidiostat halofuginone. Poultry Science 70: 1559-1563.
53. GRAU, A., CODONY, R., GRIMPA, S., BAUCELLS, M.D. and GUARDIOLA, F. (2001) Cholesterol oxidation in frozen dark chicken meat: influence of dietary fat source, and alpha-tocopherol and ascorbic acid supplemenation. Meat Science 57: 197-208.
54. GUILLOT, I., LOHR, B., WEISER, H., HALBACH, S. and RAMBECK, W.A. (1998) Influence of vitamin C on cadmium and mercury accumulation. Journal of Animal Physiology and Animal Nutrition 80: 167-169.
55. HA, T.Y., OTSUKA, M. and ARAKAWA, N. (1994) Ascorbate indirectly stimulates fatty acid utilization in primary cultured guinea pig hepatocytes by enhancing carnitine synthesis. Journal of Nutrition 124: 732-737.
56. HAAZELE, F.M., GUENTER, W., MARQUARDT, R.R. and FROHLICH, A.A. (1993) Beneficial effects of ascorbic acid supplement on hens subject to ochratoxin A toxicosis under normal and high ambient temperatures. Canadian Journal of Animal Science 73: 149-157.
57. HERBERT, V., SHAW, S. and JAYATILLEKE, E. (1996) Vitamin C-driven free radical generation from iron. Journal of Nutrition 126: 1213S-1220S.
58. JAFAR, G.H. and BLAHA, J. (1996) Effect of ascorbic acid supplementation in drinking water on growth rate, feed consumption and feed efficiency of broiler chickens maintained under acute heat stress conditions. Zivocisna Vyroba 41: 485-490
59. JONES, R.B., SATTERLEE, D.G. and CADD, G.G. (1999) Timidity in Japanese quail: effects of vitamin C and divergent selection for adrenocortical response. Physiology and Behavior 67: 117-120.
60. JONES, R.B., SATTERLEE, D.G., MOREAU, J. and WADDINGTON, D. (1996) Vitamin C supplementation and fear reduction in Japanese quail: short term cumulative effects. British Poultry Science 37: 33-42.
61. KASSIM, H. and NORZIHA, I. (1995) Effects of ascorbic acid (vitamin C) supplementation in layer and broiler diets in the tropics. Asian-Australasian Journal of Animal Science 8: 607-610.
62. KESHAVARZ, K. (1996) The effect of different levels of vitamin C and cholecalciferol with adequate or marginal levels of dietary calcium on performance and eggshell quality of laying hens. Poultry Science 75: 1227-1235.
63. KHALAFALLA, M.K. and BESSEI, W. (1998) The effect of ascorbic acid supplementation on eggshell quality of laying hens receiving saline drinking water. Archiv für Geflügelkunde 61: 172-175.
64. KUTLU, H.R. (2001) Influence of wet-feeding and supplementation with ascorbic acid on performance and carcass composition of broiler chicks exposed to high ambient temperature. Archives of Animal Nutrition 54: 127-139.
65. KUTLU, H.R. and FORBES, J.M. (1993a) Changes in growth and blood parameters in heat-stressed broiler chicks in response to dietary ascorbic acid. Livestock Production Science 36: 335-350.
66. KUTLU, H.R. and FORBES, J.M. (1993b) Effect of changes in environmental temperature on self-selection of ascorbic acid in coloured feeds by broiler chickens. Proceedings of the Nutrition Society 52: 29A.
67. KUTLU, H.R. and FORBES, J.M. (1993c) Self-selection of ascorbic acid in coloured feeds by heat-stressed broiler chicks. Physiology and Behavior 53: 103-110.
68. KUTLU, H.R. and FORBES, J.M. (1994a) Changes in growth and blood parameters in heat-stressed broiler chicks in response to dietary ascorbic acid: Livestock Production Science 36: 335-350.
69. KUTLU, H.R. and FORBES, J.M. (1994b) self-selection for ascorbic acid by broiler chicks in response to changing environmental temperature. British Poultry Science 35: 820-821.
70. LADMAKI, M.H., BUYS, N., DEWIL, E., RAHIMI, G. and DECUYPERE, E. (1997) The prophylactic effect of vitamin C supplementation on broiler ascites incidence and plasma thyroid hormone concentration. Avian Pathology 26: 33-44.
71. LAURIDSEN, C., JENSEN, C., JAKOBSEN, K., ENGBERG, R.M., ANDERSEN, J.O., JENSEN, S.K., SORENSEN, P., HENCKEL, P., SKIBSTED, L.H. and BERTELSEN, G. (1997) The influence of vitamin C on the oxidative stability of broiler meat products. Acta Agriculturae Scandinavica 47A: 187-196.
72. LEACH, R.M. and BURDETTE, J.H. (1985) The influence of ascorbic acid on the occurrence of tibial dyschondroplasia in young broiler chickens. Poultry Science 64: 1188-1191.
73. LEBOY, P.S., VAIAS, L., USCHMANN, B., GOLUB, E., ADAMS, S.L. and PACIFICI, M. (1989) Ascorbic acid induces alkaline phosphatase, type X collagen and calcium deposition in cultured chick chondrocytes. Journal of Biological Chemistry 264: 17281-17286.
74. LECHOWSKI, J. and CERMAK, B. (2000) The influence of magnesium on the contents of vitamin C in the tissues of chickens. Faculty of Agriculture in Ceske Budejovice, Series for Animal Sciences 17: 147-153.
75. LECHOWSKI, J. and NAGORNA-STASIAK, B. (1993) The effect of biotin supplementationon ascorbic acid metabolism in chickens. Archivum Veterinarium Polonicum 33: 19-27.
76. LYLE, G.R. and MORENG, R.E. (1968) Elevated environmental temperature and duration of post exposure ascorbic acid administration. Poultry Science 47: 410.
77. MARRON, I., BEDFORD, M.R. and MCCRACKEN, K.J. (2001) The effects of adding xylanase, vitamin C and copper sulphate to wheat-based diets on broiler performance. British Poultry Science 42: 493-500.
78. MAXWELL, M.H., ROBERTSON, G.W., FARQUHARSON, C. and MOSELEY, D. (1994) Ultrastructural localisation of the oxygen free radical, hydrogen peroxide, and the detection of serum troponin T for the early diagnosis of injured cardiomyocytes from broilers with ascites. Proceedings of 9th European Poultry Conference, Glasgow 2: 53-56.
79. MCCORMACK, H.A., FLEMING, R.H., MCTEIR, L. and WHITEHEAD, C.C. (2001) Bone development up to 6 weeks of age in feed restricted broiler breeders fed diets supplemented with different concentrations of ascorbic acid. British Poultry Science 42: S91-S92.
80. MCKEE, J.S. and HARRISON, P.C. (1995) Effects of supplemental ascorbic acid on the performance of broiler chickens exposed to multiple concurrent stressors. Poultry Science 74: 1772-1785.
81. MCKEE, J.S., HARRISON, P.C. and RISKOWSKI, G.L. (1997) Effects of supplemental ascorbic acid on the energy conversion of broiler chicks during heat stress and feed withdrawal. Poultry Science 76: 1278-1286.
82. MITCHELL, M.A. and KETTLEWELL. P.J. (1998) Physiological stress and welfare of broiler chickens in transit: solutions not problems. Poultry Science 77: 1803-1814.
83. MITCHELL, M.A. and SANDERCOCK, D.A. (1995) Creatine kinase isoenzyme profiles in the plasma of the domestic fowl: effects of acute heat stress. Research in Veterinary Science 59: 30-34.
84. MIYASAKI, T., SATO, M., YOSHINAKA, R. and SAKAGUCHI, M. (1995) Effect of vitamin C on lipid and carnitine metabolism in rainbow trout. Fisheries Science 61: 501-506.
85. MONSI, A. and ONITCHI, D.O. (1991) Effects of ascorbic acid (vitamin C) supplementation on ejaculated semen characteristics of broiler breeder chickens under hot and humid tropical conditions. Animal Feed Science and Technology 34: 141-146.
86. MURRAY, D.L., BRAKE, J., THAXTON, J.P. and SATTERLEE, D.G. (1988) Effect of adenocorticotropin and dietary ascorbic acid on the graft-versus-host reaction capacity of chickens. Poultry Science 67: 313-318.
87. NOLL, S.L. (2000) Vitamin C supplementation of turkey breeder diets. Zootecnica International 23: 44-47.
88. NEUMAN, S.L., ORBAN, J.I., LIN, T.L., LATOUR, M.A. and HESTER, P.Y. (2002) The effect of dietary ascorbic acid on semen traits and testis histology of male turkey breeders. Poultry Science 81: 265-268.
89. NEWMAN, S. and LEESON, S. (1999) The effect of dietary supplementation with 1,25-dihydroxycholecalciferol or vitamin C on the characteristics of the tibia of older laying hens. Poultry Science 78: 85-90.
90. ORBAN, J.I., ROLAND, D.A., CUMMINS, K. and LOVELL, R.T. (1993) Influence of large doses of ascorbic acid on performance, plasma calcium, bone characteristics and eggshell quality in broilers and Leghorn hens. Poultry Science 72: 691-700.
91. ORUWARI, B.M., MBERE, O.O. and SESE, B.T. (1995) Ascorbic acid as a supplement for Babcock hens in a tropical condition. Journal of Applied Animal Research 8: 121-128.
92. OSTROWSKI-MEISSNER, H.T. (1981) The physiological responses of broilers exposed to short-term thermal stress. Comparative Biochemistry and Physiology 70A: 1-8.
93. PARDUE, S.L. and THAXTON, J.P. (1986) Ascorbic acid in poultry: a review. World's Poultry Science Journal 42: 107-123.
94. PARDUE, S.L., THAXTON, J.P. and BRAKE, J. (1985) Role of ascorbic acid in chicks exposed to high environmental temperature. Journal of Applied Physiology 58: 1511-1516.
95. PATEL, K.P. and BAKER, D.H. (1996) Supplemental iron, copper, zinc, ascorbate, caffeineand chlortetracycline do not affect riboflavin utilization in the chick. Nutrition Research 16: 1943-1952.
96. PEEBLES, E.D., MILLER, E.H., BRAKE, J.D. and SCHULTZ, C.D. (1992) Effects of ascorbic acid on plasma thyroxine concentrations and eggshell quality of Leghorn hens treated with dietary thiouracil. Poultry Science 71: 553-559.
97. PINES, M., GRANOT, I. and HURWITZ, S. (1990) Cyclic AMP-dependent inhibition of collagen synthesis in avian epiphyseal cartilage cells: effect of chicken and human parathyroid hormone and parathyroid hormone-related peptide. Bone and Mineral 9: 23-33.
98. PINION, J.L., BILGILI, S.F. and HESS, J.B. (1995) The effects of halofuginone and salinomycin, alone and in combination, on live performance and skin characteristics of female broilers: influence of a high-protein diet supplemented with ascorbic acid and zinc. Poultry Science 74: 383-390.
99. PLEVA, J., CABADAJ, R., MATE, D., BIRES, J. and KORIMOVA, L. (1994) The role of vitamin A and ascorbic acid in accumulation of zinc in hen tissues. Folia Veterinaria 38: 41-44.
100. PROTEGGENTE,A.R., ENGLAND, T.G., RICE-EVANS, C.A. and HALLIWELL, B. (2001) Iron supplementation and oxidative damage to DNA in healthy individuals with high plasma ascorbate. Biochemical and Biophysical Research Communications 288: 245-251.
101. PURON, D., SANTAMARIA, R. and SEGURA, J.C. (1994) Effects of sodium bicarbonate, acetylsalicylic and ascorbic acid on broiler performance in a tropical environment. Journal of Applied Poultry Research 3: 141-145.
102. PUTHPONGSIRIPORN, U., SCHEIDELER, S.E., SELL, J.L. and BECK, M.M. (2001) Effects of vitamin E and C supplementation on performance, in vitro lymphocyte proliferation and antioxidant status of laying hens during heat stress. Poultry Science 80: 1190-1200.
103. RAJA, A.Q. and QURESHI, A. (2000) Effectiveness of supplementation of vitamin C in broiler feeds in hot season. Pakistan Veterinary Journal 20: 100.
104. RAMBECK, W.A. and KOLLMER, W.E. (1990) Modifying cadmium retention in chickens by dietary supplements. Journal of Animal Physiology and Animal Nutrition 63: 66-74.
105. RAMBECK, W.A and WEISER, H. (1992) Reduction of tissue cadmium retention by L-ascorbic acid. Proceedings of 19th World's Poultry Congress, Amsterdam, 2: 20-24.
106. RENNIE, J.S. and WHITEHEAD, C.C. (1996) The effectiveness of dietary 25- and 1-hydroxycholecalciferol in combating tibial dyschondroplasia in broiler chickens. British Poultry Science 37: 413-422.
107. RENNIE, J.S., MCCORMACK, H.A., FARQUHARSON, C. BERRY. J.L., MAWER, E.B. and WHITEHEAD, C.C. (1995) Interaction between dietary 1,25-dihydroxycholecalciferol and calcium and effects of management on the occurrence of tibial dyschondroplasia, leg abnormalities and performance in broiler chickens. British Poultry Science 36: 465-477.
108. RENNIE, J.S., FLEMING, R.H., MCCORMACK, H.A., MCCORQUODALE, C.C. and WHITEHEAD, C.C. (1997) Studies on effects of nutritional factors on bone structure and osteoporosis in laying hens. British Poultry Science 38: 417-424.
109. ROBERSON, K.D. and EDWARDS, H.M. Jr (1994) Effects of ascorbic acid and 1,25-dihydroxycholecalciferol on alkaline phosphatase and tibial dyschondroplasia in broiler chickens. British Poultry Science 35: 763-773.
110. SAHOTA, A.W. and GILLANI, A.H. (1995) Effect of ascorbic acid supplementation on performance and cost of production in layers maintained under high ambient temperatures. Pakistan Veterinary Journal 15: 155-158.
111. SATTERLEE, D.G., JONES, R.B. and RYDER, F.H. (1993) Effects of vitamin C supplementation on the adrenocortical and tonic immobility fear reactions of Japanese quail genetically selected for high corticosterone response to stress. Applied Animal Behaviour Science 35: 347-357.
112. SATTERLEE, D.G., JONES, R.B. and RYDER, F.H. (1994) Effects of ascorbyl-2-polyphosphate (APP) on adrenocortical activation and fear-related behaviour in broiler chickens. Poultry Science 73: 194-201.
113. SAYED, A.N. and SHOEIB, H. (1996) A rapid two weeks-evaluation of vitamin C and B-complex and sodium chloride for heat-stressed broilers. Assiut Veterinary Medical Journal 34: 37-42.
114. SELYE, H. (1936) A syndrome produced by diverse nocuous agents. Nature 7: 32-36.
115. SOMASHEKHARAIAH, B.V. and PRASAD, A.R.K. (1991) Indian Journal of Medical Research 94B: 387-390.
116. SRIGIRIDHAR, K. and NAIR, K.M. (2000) Supplementation with alpha-tocopherol or a combination of alpha-tocopherol and ascorbic acid protects the gastrointestinal tract of iron-deficient rats against iron-induced oxidative damage during iron repletion. British Journal of Nutrition 84: 165-173.
117. SURAI, P.F., KUKLENKO, T.V., IONOV, I.A., NOBLE, R.C. and SPARKS, N. (2000) Effect of vitamin A on the antioxidant system of the chick during early postnatal development. British Poultry Science 41: 454-458.
118. SURAI, P.F. and KUKLENKO, T.V. (2000) Effects of vitamin A on the antioxidant systems of the growing chicken. Asian-Australasian Journal of Animal Sciences 13: 1290-1295.
119. SURAI, P.F., IONOV, I.A., KUKLENKO, T.V., KOSTJUL, I.A., MACPHERSON, A., SPEAKE, B.K., NOBLE, R.C. and SPARKS, N. (1998) Effect of supplementing the hen's diet with vitamin A on the accumulation of vitamins A and E, ascorbic acid and carotenoids in the egg yolk and in the embryonic liver. British Poultry Science 39: 257-263.
120. SUSHIL, P., AGGARWAL, C.K. and CHOPRA, S.K. (1998a). Effect of feeding antistress agents on the performance of egg type pullets housed in cages during summer. Indian Journal of Poultry Science 33: 1-7.
121. SUSHIL, P., AGGARWAL, C.K. and CHOPRA, S.K. (1998b) Effect of supplementation of anti stress agents in the ration on egg quality of pullets during summer. Indian Journal of Animal Sciences 68: 667-668.
122. TAKAHASI, K. and AKIBA, Y. (1999) Effect of oxidised fat on performance and some physiological responses in broiler chickens. Japanese Poultry Science 36: 304-310.
123. TAKAHASHI, K., AKIBA, Y. and HORIGUCHI, M. (1991) Effects of supplemental ascorbic acid on performance, organ weight and plasma cholesterol concentration in broilers treated with propylthiouracil. British Poultry Science 32: 545-554.
124. TOLBERT, L.C., THOMAS, T.N. MIDDAUGH, L.D. and ZEMP, J.W. (1979) Effects of ascorbic acid on neurochemical, behavioural and physiological systems mediated by catecholamines. Life Science 25: 2189-2195.
125. TOUSSANT, M.J. and LATSHAW, J.D. (1994) Evidence of multiple metabolic routes in vanadium's effects on layers. Ascorbic acid differential effects on prepeak egg production parameters following prolonged vanadium feeding. Poultry Science 73: 1572-1580.
126. WALTON, J.P., JULIAN, R.J. and SQUIRES, E.J. (2001) The effects of dietary flax oil and antioxidants on ascites and pulmonary hypertension in broilers using a low temperature model. British Poultry Science 42: 123-129.
127. WEN, J., LIN, J. and WANG, H.M. (1997) Effect of dietary vitamin E and ascorbic acid on the growth and immune function of chicks. Chinese Agricultural Sciences 145-149.
128. WHITEHEAD, C.C., FARQUHARSON,C., RENNIE J.S. and MCCORMACK, H.A. (1994). Nutrition and cellular factors affecting tibial dyschondroplasia in broilers. Proceedings of the Australian Poultry Science Symposium, Sydney, 13-19.
129. WU, C.C., DORAIRAJAN, T. and LIN, T.L. (2000) Effect of ascorbic acid supplementation on the immune response of chickens vaccinated and challenged with infectious disease virus. Veterinary Immunology and Immunopathology 74: 145-152.
130. UBOSI, C.O. and GANDU, F.D. (1995) Effect of dietary treatments of ascorbic acid on productive performance and egg quality of caged laying chickens in the semi-arid zone of Nigeria. Discovery and Innovation 7: 77-82.
131. YOSELEWITZ, I., BALNAVE, D. and DIXON, R.J. (1988) Factors influencing the production of defective eggshells by laying hens receiving sodium chloride in the drinking water. Nutrition Reports International 38: 697-703.
132. ZAKARIA, A.H., LATIF, A.A. and AL-ANEZI, M.A. (1998) Effect of ascorbic acid on embryonic development, hatch time and growth of extended placement of broiler chickens. Archiv für Geflügelkunde 62: 11-15.
133. ZAKARIA, A.H. and AL-ANEZI, M.A. (1966) Effect of ascorbic acid and cooling during egg incubation on hatchability, culling, mortality and the body weights of broiler chickens. Poultry Science 75: 1204-1209.
134. ZAPATA, L.F. and GERNAT, A.G. (1994) The effect of four levels of ascorbic acid and two levels of calcium on eggshell quality of forced-moulted White Leghorn hens. Poultry Science 74: 1049-1052.
135. ZULKIFLI, I., NORMA, M.T.C., CHONG, C.H. and LOH, T.C. (2001) The effects of crating and road transportation on stress and fear responses of broiler chickens treated with ascorbic acid. Archiv für Geflügelkunde 65: 33-37.