Low leucocyte myeloperoxidase activity in patients with multiple sclerosis

Journal of Neurology Neurosurgery and Psychiatry

Volumn 74, Issue 7, 2003, Pages 953-955

  Ramsaransing, G ^a   Teelken, A ^a   Prokopenko, V M ^b   Arutjunyan, A V ^b   De Keyser, J ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; MYELOPEROXIDASE; TETRAMETHYLBENZIDINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; LEUKOCYTE; MALE; MULTIPLE SCLEROSIS; OXIDATION; PATHOGENESIS; PRIORITY JOURNAL; SPECTROPHOTOMETRY;

EID: 0037803722     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.74.7.953     Document Type: Article

References (23)

1. Hoy A, Leininger-Muller B, Kutter D, et al. Growing significance of myeloperoxidase in non-infectious diseases. Clin Chem Lab Med 2002;40:2-8.
2. Nagra RM, Becher B, Tourtellotte WW, et al. Immunohistochemical and genetic evidence of myeloperoxidase involvement in multiple sclerosis. J Neuroimmunol 1997;78:97-107.
3. Reynolds WF, Rhees J, Maciejewski D, et al. Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease. Exp Neurol 1999;155:31-41.
4. Kuokkanen S, Gschwend M, Rioux JD, et al. Genomewide scan of multiple sclerosis in Finnish multiplex families. Am J Hum Genet 1997;61:1379-87.
5. Sawcer S, Jones HB, Feakes R, et al. A genome screen in multiple sclerosis reveal susceptibility loci on chromosome 6p21 and 17q22. Nat Genet 1996;13:464-8.
6. Chataway J, Sawcer S, Feakes R, et al. A screen of candidates from peaks of linkage: evidence for the involvement of myeloperoxidase in multiple sclerosis. J Neuroimmunol 1999;98:208-13.
7. Kantarci OH, Atkinson EJ, Hebrink DD, et al. Association of a myeloperoxidase promoter polymorphism with multiple sclerosis. J Neuroimmunol 2000;105:189-94.
8. Nelissen I, Fiten P, Vandenbroeck K, et al. PECAM1, MPO and PRKAR1A at chromosome 17q21-q24 and susceptibility for multiple sclerosis in Sweden and Sardinia. J Neuroimmunol 2000;108:153-9.
9. Brennan M, Gaur A, Pahuja A, et al. Mice lacking myeloperoxidase are more susceptible to experimental autoimmune encephalomyelitis. J Neuroimmunol 2001;112:97-105.
10. Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227-31.
11. Percy AK, Brady RO. Metachromatic leukodystrophy: diagnosis with samples of venous blood. Science 1968;161:594-5.
12. Naito Y, Yoshikawa T, Matsuyama K, et al. Neutrophils, lipid peroxidation, and nitric oxide in gastric reperfusion injury in rats. Free Radic Biol Med 1998;24:494-502.
13. Trotter JL, Pelfrey CM, Trotter AL, et al. T cell recognition of myelin proteolipid protein and myelin proteolipid protein peptides in the peripheral blood of multiple sclerosis and control subjects. J Neuroimmunol 1998;84:172-8.
14. Martin R, Jaraquemada D, Flerlage M, et al. Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals. J Immunol 1990;145:540-8.
15. Hellings N, Baree M, Verhoeven C, et al. T-cell reactivity to multiple myelin antigens in multiple sclerosis patients and healthy controls. J Neurosci Res 2001;63:290-302.
16. Wucherpfennig KW, Strominger JL. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell 1995;80:695-705.
17. Hellings N, Gelin G, Medaer R, et al. Longitudinal study of antimyelin T-cell reactivity in relapsing-remitting multiple sclerosis: association with clinical and MRI activity. J Neuroimmunol 2002;126:143-60.
18. Wright CE, Lin TT, Lin YY, et al. Taurine scavenges oxidized chlorine in biological systems. Prog Clin Biol Res 1985;179:137-47.
19. Park E, Jia J, Quinn MR, et al. Taurine chloramine inhibits lymphocyte proliferation and decreases cytokine production in activated human leukocytes. Clin Immunol 2002;102:179-84.
20. Marcinkiewicz J, Nowak B, Grabowska A, et al. Regulation of murine dendritic cell functions in vitro by taurine chloramine, a major product of the neutrophil myeloperoxidase-halide system. Immunology 1999;98:371-8.
21. Marcinkiewicz J, Chain B, Nowak B, et al. Antimicrobial and cytotoxic activity of hypochlorous acid: interactions with taurine and nitrite. Inflamm Res 2000;49:280-9.
22. Butterfield RJ, Sudweeks JD, Blankenhorn EP, et al. New genetic loci that control susceptibility and symptoms of experimental allergic encephalomyelitis in inbred mice. J Immunol 1998;161:1860-7.
23. Hoy A, Tregouet D, Leininger-Muller B, et al. Serum myeloperoxidase concentration in a healthy population: biological variations, familial resemblance and new genetic polymorphisms. Eur J Hum Genet 2001;9:780-6.