Association of a myeloperoxidase promoter polymorphism with multiple sclerosis

Journal of Neuroimmunology

Volumn 105, Issue 2, 2000, Pages 189-194

  Kantarci, Orhun H ^a   Atkinson, Elizabeth J ^a   Hebrink, David D ^a   McMurray, Cynthia T ^b   Weinshenker, Brian G ^a  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

Genetics; Multiple sclerosis; Myeloperoxidase; Prognosis; Susceptibility

Indexed keywords

MYELOPEROXIDASE;

ADULT; ARTICLE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; PROGNOSIS;

ADULT; FEMALE; GENOTYPE; HUMANS; MALE; MULTIPLE SCLEROSIS; PEROXIDASE; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS);

EID: 0034717829     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(00)00198-3     Document Type: Article

References (18)

1. Austin G.E., Lam L., Zaki S.R., Chan W.C., Hodge T., Hou J., Swan D., Zhang W., Racine M., Whitsett C., Brown B. Sequence comparison of putative regulatory DNA of the 5′ flanking region of the myeloperoxidase gene in normal and leukemic bone marrow cells. Leukemia. 7:1993;1445-1450.
2. Chataway J., Sawcer S., Feakes R., Coraddu F., Broadley S., Jones H.B., Clayton D., Gray J., Goodfellow P.N., Compston A. A screen of candidates from peaks of linkage: evidence for the involvement of myeloperoxidase in multiple sclerosis. J Neuroimmunol. 98:(2):1999;208-213.
3. Hazen S.L., Heinecke J.W. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J. Clin. Invest. 99:(9):1997;2075-2081.
4. Josephy P.D. The role of peroxidase-catalyzed activation of aromatic amines in breast cancer. Mutagenesis. 11:1996;3-7.
5. Kantarci O., Siva A., Eraksoy M., Karabudak R., Sutlas N., Agaoglu J., Turan F., Ozmenoglu M., Togrul E., Demirkiran M. Survival and predictors of disability in Turkish MS patients. Neurology. 51:(3):1998;765-772.
6. Kuokkanen S., Gschwend M., Rioux J.D., Daly M.J., Terwilliger J.D., Tienari P.J., Wikstrom J., Palo J., Stein L.D., Hudson T.J., Lander E.S., Peltonen L. Genomewide scan of multiple sclerosis in Finnish multiplex families. Am. J. Human Genet. 61:(6):1997;1379-1387.
7. London S.J., Lehman T.A., Taylor J.A. Myeloperoxidase geneytic polymorphism and lung cancer risk. Cancer Res. 57:1997;5001-5003.
8. Nagra R.M., Becher B., Tourtellotte W.W., Antel J.P., Gold D., Paladino T., Smith R.A., Nelson J.R., Reynolds W.F. Immunohistochemical and genetic evidence of myeloperoxidase involvement in multiple sclerosis. J. Neuroimmunol. 78:1997;97-107.
9. Pero R.W., Sheng Y., Olsson A., Bryngelsson C., Lund-Pro M. Hypochlorous acid/N-chloramines are naturally produced DNA repair inhibitors. Carcinogenesis. 17:1996;13-18.
10. Piedrafita F.J., Molander R.B., Vansant G., Orlova E.A., Pfhal M., Reynolds W.F. An alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormone-retinoic acid response element. J. Biol. Chem. 271:1996;14412-14420.
11. Reynolds W.F., Chang E., Douer D., Ball E.D., Kanda V. An allelic association implicates myeloperoxidase in the etiology of acute promyelocytic leukemia. Blood. 90:(7):1997;2730-2737.
12. Reynolds W.F., Rhees J., Maciejewski D., Paladino T., Sieburg H., Maki R.A., Masliah E. Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease. Exp. Neurol. 155:(1):1999;31-41.
13. Rodriguez M., Siva A., Ward J., Stolp-Smith K., O'Brien P., Kurland L. Impairment, disability, and handicap in multiple sclerosis: a population-based study in Olmsted County, Minnesota. Neurology. 44:1994;78-83.
14. Sawcer S., Jones H.B., Feakes R., Gray J., Smaldon N., Chataway J., Robertson N., Clayton D., Goodfellow P.N., Compston A. A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nature Genet. 13:(4):1996;464-468.
15. Sommer S.S., Groszbach A.R., Bottema C.D. PCR amplification of specific alleles is a general method for rapidly detecting known single base changes. BioTechniques. 12:1992;82-87.
16. Weinshenker B.G. The natural history of multiple sclerosis. Neurol. Clin. 1:1995;119-146.
17. Weinshenker B.G., Wingerchuk D.M., Liu Q., Bissonet A.S., Schaid D.J., Sommer S.S. Genetic variation in the tumor necrosis factor alpha gene and the outcome of multiple sclerosis. Neurology. 49:(2):1997;378-385.
18. Weinshenker B.G., Santrach P., Bissonet A.S., McDonnell S.K., Schaid D.J., Moore S.B., Rodriguez M. Major histocompatibility complex class II alleles and the course and outcome of MS: a population-based study. Neurology. 51:(3):1998;742-747.