Roles of kappa opioid receptors in cardioprotection against ischemia - The signaling mechanisms

Acta Physiologica Sinica

Volumn 55, Issue 2, 2003, Pages 115-120

  Wong, Tak Ming ^a   Wu, Song ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Adrenoceptor; Ischemic preconditioning; Kappa opioid receptor; Myocardial ischemia

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; ADENOSINE TRIPHOSPHATE; ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; CALCIUM ION; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; POTASSIUM CHANNEL; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ADRENERGIC STIMULATION; AUTOCRINE EFFECT; ENZYME ACTIVATION; HEART ARRHYTHMIA; HEART FUNCTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; NONHUMAN; OXYGEN CONSUMPTION; PARACRINE SIGNALING; PATHOPHYSIOLOGY; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SHORT SURVEY;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CALCIUM; CARDIOTONIC AGENTS; HUMANS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, OPIOID, KAPPA; SIGNAL TRANSDUCTION;

EID: 0037799354     PISSN: 03710874     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (38)

1. Ventura C, Bastagli L, Bernardi P, Caldarera CM, Guamieri C. Opioid receptor in the cardiac sarcolemma: Effect of phenylephrine and isoproterenol. Biochim Biophys Acta 1989;987:69-74.
2. 3H]-69593 binding sites in the rat heart by receptor binding studies. J Mol Cell Cardiol 1991;23:1297 -1302.
3. Wong TM, Lee AYS, Tai KK. Effects of drugs interacting with opioid receptors during normal perfusion or ischaemia and reperfusion-an attempt to identify cardiac opioid receptor subtype (s) involved in arrhythmogenesis. J Mol Cell Cardiol 1990;22:1167-1175.
4. 2+ in cardiac myocytes. Am J Physiol 1991;261:H1671-H1674.
5. Xia Q, Shen JZ, Tai KK, Wong TM. Effect of chronic U50488H treatment on binding and mechanical responses of the rat hearts. J Pharmacol Exp Ther 1994;268:930-934.
6. i in myocytes. Am J Physiol 1997;272:C560-C564.
7. Weihe E, McKnight AT, Corbett AD, Kosterlitz HW. Proenkephalin- and pro-dynorphin-derived peptides in guinea-pig heart. Neuropeptides 1985;5:453-456.
8. Canossa M, Ventura C, Vaona I, Carboni L, Guarnieri C, Spampinato S. Prodynorphin mRNA expression in adult cultured rat ventricular cardiac myocytes. Biochim Biophys Acta 1993;1172:247-250.
9. Yu XC, Li HY, Wang HX, Wong TM. U50488H inhibits effects of norepinephrine in rat cardiomyocytes-cross talk between κ-opioid and β-adrenergic receptors. J Mol Cell Cardiol 1998;30:405-413.
10. Chakraborti S, Chakraborti T, Shaw G. β-Adrenergic mechanisms in cardiac diseases, a perspective. Cell Sign 2000;12:499-513.
11. Yu XC, Wang HX, Pei JM, Wong TM. Anti-arrhythmic effect of κ-opioid receptor stimulation in the perfused rat heart: involvement of a cAMP-dependent pathway. J Mol Cell Cardiol 1999;31:1809-1819.
12. Pepe S, Xiao R, Hohl C, Altschuld R, Lakatta EG. 'Cross talk' between opioid peptide and adrenergic receptor signaling in isolated rat heart. Circulation 1997; 95:2122-2129.
13. Xiao R, Pepe S, Spurgeon HA, Capogrossi MC, Lakatta EG. Opioid peptide receptor stimulation reverses β-adrenergic effects in rat heart cells. Am J Physiol 1997; 272:H797-H805.
14. Yu XC, Diao TM,Pei JM, Zhang WM, Wong NS, Wong TM. κ-Opioid receptor agonist inhibits the cholera toxinsensitive G protein in the heart. J Cardiovasc Pharmacol 2002;38:232-239.
15. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 1986;74:1124-1136.
16. Armstrong SC, Downey JM, Ganote CE. Preconditioning of isolated rabbit cardiomyocytes: induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor. Cardiovasc Res 1994;28:72-77.
17. Iwaki K, Chi SH, Dillmann WH, Mestril R. Induction of HSP70 in cultured rat neonatal cardiomyocytes by hypoxia and metabolic stress. Circulation 1993;87:2023-2032.
18. Nayeem MA, Hess ML, Qian YZ, Loesser KE, Kukreja RC. Delayed preconditioning of cultured adult rat cardiac myocytes: role of 70- and 90-kDa heat stress proteins. Am J Physiol 1997;273:H861-H868.
19. Radford NB, Fina M, Benjamin IJ, Moreadith RW, Graves KH, Zhao P, Gavva S, Wiethoff A, Sherry AD, Malloy CR, Williams RS. Cardioprotective effects of 70-kDa heat shock protein in transgenic mice. Proc Natl Acad Sci USA 1996;93:2339-2342.
20. Marber MS, Latchman DS, Walker JM, Yellon DM. Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction. Circulation 1993;88:1264-1272.
21. Cohen MV, Yang XM, Liu GS. Acetylcholine, bradykinin, opioids and phenylephrine, but not adenosine, triggers preconditioning by generating free radicals and opening mitochondrial K (ATP) channels. Circ Res 2001; 89:273-278.
22. Wang GY, Wu S, Pei JM, Yu XC, Zhou JJ, Wong TM. κ- but not δ-opioid receptors mediate effects of ischemic preconditioning on both infarct and arrhythmias in rats. Am J Physiol 2001;280:H384-H391.
23. Wu S, Li HY, Wong TM. Cardioprotection of preconditioning by metabolic inhibition in the rat ventricular myocyte-involvement of κ-opioid receptor. Circ Res 1999; 84:1388-1395.
24. Ho JCS, Wu S, Kam KWL, Sham JSK, Wong TM. Effects of pharmacological preconditioning with U50488H on calcium homeostasis in rat ventricular myocytes subjected to metabolic inhibition and anoxia. Br J Pharmacol 2002;137:739-748.
25. Schultz JE, Gross GJ. Opioids and cardioprotection. Pharmacol Ther 2001;89:123-137.
26. Wang GY, Zhou JJ, Shan J, Wong TM. Protein kinase C-ε is a trigger of delayed cardioprotection of κ-opioid receptor stimulation in the rat heart. J Pharmacol Exp Ther 2001;299:603-610.
27. Qiu Y, Ping P, Tang XL, Manchikalapudi S, Rizvi A, Zhang J, Takano H, Wu WJ, Bolli R. Direct evidence that protein kinase C plays an essential role in the development of late preconditioning against myocardial stunning in conscious rabbits and that epsilon is the isoform involved. J Clin Invest 1998;101:2182-2198.
28. Ping P, Takano H, Zhang J, Tang XL, Qiu Y, Li RC, Banerjee S, Dawn B, Balafonova Z, Bolli R. Isoform-selective activation of protein kinase C by nitric oxide in the heart of conscious rabbits: a signaling mechanism for both nitric oxide-induced and ischemia-induced preconditioning. Circ Res 1999;84:587-604.
29. ATP channels. Circ Res 1999;84:846-851.
30. ATP channel elicits late preconditioning against myocardial infarction via protein kinase C signaling pathway. Circ Res 1999;85:1146-1153.
31. Wang S, Cone J, Liu Y. Dual roles of mitochondrial K (ATP) channels in diazoxide -mediated protection in isolated rabbit hearts. Am J Physiol 2001;280:H246-H255.
32. ATP channels in ischemic preconditioning of the canine heart. Am J Physiol 2001; 280:H256-H263.
33. Sato T, Sasaki N, Seharaseyon J, O'Rourke B, Marban E. Selective pharmacological agents implicate mitochondrial but not sarcolemmal K (ATP) channels in ischemic cardioprotection. Circulation 2000;101:2418-2423.
34. Tonkovic-Capin M, Gross GJ, Bosnjak ZJ, Tweddell JS, Fitzpatrick CM, Baker JE. Delayed cardioprotection by isoflurane: role of K (ATP) channels. Am J Physiol 2002;283:H61-H68.
35. Patel HH, Hsu AK, Peart JN, Gross GJ. Sarcolemmal K (ATP) channel triggers opioid-induced delayed cardioprotection in the rat. Circ Res 2002;91:186-188.
36. Zhou JJ, Pei JM, Wang GY, Wu S, Wang WP, Cho CH, Wong TM. Inducible heat shock protein 70 mediates delayed cardioprotection of U50488H pretreatment in rat ventricular myocytes. Am J Physiol 2001;281:H40-H47.
37. Steenbergen C, Murphy E, Watts JA, London RE. Correlation between cytosolic free calcium, contracture, ATP, and irreversible ischemic injury in perfused rat heart. Circ Res 1990;66:135-146.
38. Ylitalo KV, Ala-Rami A, Liimatta EV, Peukurinen KJ, Hassinen E. Intracellular free calcium and mitochondrial membrane potential in ischemia/reperfusion and preconditioning. J Mol Cell Cardiol 2000;32:1223-1238.