Emx2 is required for growth of the hippocampus but not for hippocampal field specification

Journal of Neuroscience

Volumn 20, Issue 7, 2000, Pages 2618-2625

  Tole, Shubha ^a,c   Goudreau, Guy ^b   Assimacopoulos, Stavroula ^a   Grove, Elizabeth A ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^c TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

Cortical hem; Cortical maturation; Emx2; Hippocampus; Patterning; Specification

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN CORTEX; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CYTOARCHITECTURE; DENTATE GYRUS; EMBRYO; EMBRYO PATTERN FORMATION; GENE EXPRESSION; HIPPOCAMPUS; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL;

EID: 0034175487     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-07-02618.2000     Document Type: Article

References (41)

1. Altman J, Bayer SA (1990a) Migration and distribution of two populations of hippocampal granule cell precursors during the perinatal and postnatal periods. J Comp Neurol 301:365-381.
2. Altman J, Bayer SA (1990b) Mosaic organization of the hippocampal neuroepithelium and the multiple germinal sources of dentate granule cells. J Comp Neurol 301:325-342.
3. Altman J, Bayer SA (1990c) Prolonged sojourn of developing pyramidal cells in the intermediate zone of the hippocampus and their settling in the stratum pyramidale. J Comp Neurol 301:343-364.
4. Angevine JB (1965) Time of neuron origin in the hippocampal region. Exp Neurol Suppl 2:1-70.
5. Bishop KM, Leingartner A, Richards LJ, O'Leary DDM (1999) Emx2 imparts area identity to mammalian neocortex. Soc Neurosci Abstr 25:501.
6. Caviness VS (1973) Time of neuron origin in the hippocampus and dentate gyrus of normal and reeler mutant mice: an autoradiographic analysis. J Comp Neurol 151:113-120.
7. Caviness VS, Sidman RL (1973) Time of origin of corresponding cell classes in the cerebral cortex of normal and reeler mutant mice: an autoradiographic analysis. J Comp Neurol 148:141-151.
8. Frantz GD, Bohner AP, Akers RM, McConnell SK (1994) Regulation of the POU domain gene SCIP during cerebral cortical development. J Neurosci 14:472-485.
9. Furuta Y, Piston DW, Hogan BL (1997) Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development. Development 124:2203-2212.
10. Grove EA, Tole S, Limon J, Yip L, Ragsdale CW (1998) The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice. Development 125:2315-2325.
11. Gulisano M, Broccoli V, Pardini C, Boncinelli E (1996) Emx1 and Emx2 show different patterns of expression during proliferation and differentiation of the developing cerebral cortex. Eur J Neurosci 8:1037-1050.
12. He X, Trcacy MN, Simmons DM, Ingraham HA, Swanson LW, Rosenfeld MG (1989) Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature 340:35-42.
13. Lee SM, Tole S, Grove EA, McMahon AP (2000) A local Wnt3a signal is required for development of the mammalian hippocampus. Development 127:457-467.
14. Lumsden A, Krumlauf R (1996) Patterning the vertebrate neuraxis. Science 274:1109-1115.
15. MacKenzie A, Ferguson MW, Sharpe PT (1991) Hox-7 expression during murine craniofacial development. Development 113:601-611.
16. Mallamaci A, lannone R, Briata P, Pintonello L, Mercurio S, Boncinelli E, Corte G (1998) EMX2 protein in the developing mouse brain and olfactory area. Mech Dev 77:165-172.
17. Maruyama S, D'Agostino AN (1967) Cell necrosis in the central nervous system of normal rat fetuses. An electron microscopic study. Neurology 17:550-558.
18. McConnell SK (1995) Constructing the cerebral cortex: neurogenesis and fate determination. Neuron 15:761-768.
19. Motro B, van der Kooy D, Rossant J, Reith A, Bernstein A (1991) Contiguous patterns of c-kit and steel expression: analysis of mutations at the W and SI loci. Development 113:1207-1221.
20. Nauta WJH, Feirtag M (1986) Fundamental neuroanatomy. New York: Freeman.
21. Nicholson-Flynn K, Hitchcock-DcGregori SE, Levitt P (1996) Restricted expression of the actin-regulatory protein, tropomyosin, defines distinct boundaries, evaginating neuroepithelium, and choroid plexus forerunners during early CNS development. J Neurosci 16:6853-6863.
22. Nowakowski RS, Rakic P (1981) The site of origin and route and rate of migration of neurons to the hippocampal region of the rhesus monkey. J Comp Neurol 196:129-154.
23. O'Leary DD, Schlaggar BL, Tuttle R (1994) Specification of neocortical areas and thalamocortical connections. Annu Rev Neurosci 17:419-439.
24. Pellegrini M, Mansouri A, Simeone A, Boncinelli E, Gruss P (1996) Dentate gyrus formation requires Emx2. Development 122:3893-3898.
25. Porter FD, Drago J, Xu Y, Cheema SS, Wassif C, Huang SP, Lee E, Grinberg A, Massalas JS, Bodine D, Alt F, Westphal H (1997) Lhx2, a LIM homeobox gene, is required for eye, forebrain, and definitive erythrocyte development. Development 124:2935-2944.
26. Rakic P, Nowakowski RS (1981) The time of origin of neurons in the hippocampal region of the rhesus monkey. J Comp Neurol 196:99-128.
27. Shigemoto R, Yokota Y, Tsuchida K, Nakanishi S (1990) Cloning and expression of a rat neuromedin K receptor cDNA. J Biol Chem 265:623-628.
28. Simeone A, Acampora D, Gulisano M, Stornaiuolo A, Boncinelli E (1992a) Nested expression domains of four homeobox genes in developing rostral brain. Nature 358:687-690.
29. Simeone A, Gulisano M, Acampora D, Stronaiuolo A, Rambaldi M, Boncinelli E (1992b) Two vertebrate homeobox genes related to the Drosaphila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J 11:2541-2550.
30. Stanfield BB, Cowan WM (1979) The development of the hippocampus and dentate gyrus in normal and reeler mice. J Comp Neurol 185:423-459.
31. Sturrock RR (1979) A morphological study of the development of the mouse choroid plexus. J Anat 129:777-793.
32. Theiler K (1989) The house mouse. New York: Springer.
33. Thomas T, Dziadek M (1993) Capacity to form choroid plexus-like cells in vitro is restricted to specific regions of the mouse neural ectoderm. Development 117:253-262.
34. Tole S, Grove EA (1998) Early regional patterning of the medial telencephalon. Soc Neurosci Abstr 24:785.
35. Tole S, Patterson PH (1995) Regionalization of the developing forebrain: a comparison of FORSE-1. Dlx-2 and BF-1. J Neurosci 15:970-980.
36. Tole S, Christian C, Grove EA (1997) Early specification and autonomous development of cortical fields in the mouse hippocampus. Development 124:4959-4970.
37. Wisden W, Seeburg PH (1993) A complex mosaic of high-affinity kainate receptors in rat brain. J Neurosci 13:3582-3598.
38. Xuan S, Baptista CA, Balas G, Tao W, Soares VC, Lai E (1995) Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron 14:1141-1152.
39. Yoshida M, Suda Y, Matsuo I, Miyamoto N, Takeda N, Kuratani S, Aizawa S (1997) Emx1 and Emx2 functions in development of dorsal telencephalon. Development 124:101-111.
40. Zaki W (1981) Ultrastructure of the choroid plexus and its development in the mouse. Z Mikrosk Anat Forsch 95:919-935.
41. Zaki W, Van der Loos H (1980) [A new concept about the morphogenesis of the prosencephalon in mammals (translated from French)]. Arch Anat Microsc Morphol Exp 69:123-134.