Reversible modulation of GABAA receptor-mediated currents by light is dependent on the redox state of the receptor

European Journal of Neuroscience

Volumn 17, Issue 10, 2003, Pages 2077-2083

  Leszkiewicz, Daniel N ^a   Aizenman, Elias ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Ion channel; Modulation; Rat

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BRAIN CELL; CELL POPULATION; CHINESE HAMSTER; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EMBRYO; FEMALE; GABAERGIC TRANSMISSION; HORMONE RECEPTOR INTERACTION; LIGHT; LIGHT EXPOSURE; MEMBRANE CURRENT; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; RECEPTOR INTRINSIC ACTIVITY; REDUCTION; RETINA GANGLION CELL; STIMULUS RESPONSE;

ALLOSTERIC REGULATION; ANIMALS; CEREBRAL CORTEX; CHO CELLS; CRICETINAE; EXCITATORY AMINO ACID AGONISTS; GAMMA-AMINOBUTYRIC ACID; ION CHANNEL GATING; LIGHT; MEMBRANE POTENTIALS; N-METHYLASPARTATE; NEURONS; OXIDATION-REDUCTION; RATS; RECEPTORS, GABA-A;

EID: 0037795496     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02656.x     Document Type: Article

References (33)

1. Aizenman, E., Frosch, M.P. & Lipton, S.A. (1988) Responses mediated by excitatory amino acid receptors in solitary retinal ganglion cells from rat. J. Physiol. (Lond.), 396, 75-91.
2. A receptors by redox reagents. J. Physiol. (Lond.), 517, 35-50.
3. Ascher, P., Bregestovski, P. & Nowak, L. (1988) N-methyl-D-aspartate-activated channels of mouse central neurones in magnesium-flee solutions. J. Physiol. (Lond.), 399, 207-226.
4. Barres, B.A., Silverstein, B.E., Corey, D.P. & Chun, L.L.Y. (1988) Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning. Neuron, 1, 791-803.
5. Baumann, S.W., Baur, R. & Sigel, E. (2001) Subunit arrangement of γ-aminobutyric acid type A receptors. J. Biol. Chem., 276, 36275-36280.
6. Boeckman, F.A. & Aizenman, E. (1996) Pharmacological properties of acquired excitotoxicity in Chinese hamster ovary cells transfected with N-methyl-D-aspartate receptor subunits. J. Pharmacol. Exp. Therapeutics, 279, 515-523.
7. Brimecombe, J.C., Boeckman, F.A. & Aizenman, E. (1997) Functional consequences of NR2 subunit composition in single recombinant N-methyl-D-aspartate receptors. Proc. Natl Acad. Sci. USA, 94, 11019-11024.
8. Brimecombe, J.C., Potthoff, W.K. & Aizenman, E. (1999) A critical role of the N-methyl-D-aspartate (NMDA) receptor subunit (NR) 2A in the expression of redox sensitivity of NR1/NR2A recombinant NMDA receptors. J. Pharmacol. Exp. Therapeutics, 291, 785-792.
9. Broillet, M.C. & Firestein, S. (1996) Direct activation of the olfactory cyclic nucleotide-gated channel through modification of sulfhydryl groups by NO compounds. Neuron, 16, 377-385.
10. Casado, M. & Ascher, P. (1998) Opposite modulation of NMDA receptors by lysophospholipids and arachidonic acid: common features with mechanosensitivity. J. Physiol. (Lond.), 513, 317-330.
11. Chang, Y., Xie, Y. & Weiss, D.S. (2001) Positive allosteric modulation by ultraviolet irradiation on GABA (A), but not GABA (C), receptors expressed in Xenopus oocytes. J. Physiol. (Lond.), 536, 471-478.
12. Chung, S.H. & Kuyucak, S. (1995) Changes in the kinetics and conductance of N-methyl-D-aspartate (NMDA)-receptor activated single channels with temperature. Neurosci. Lett., 187, 181-184.
13. Fukada, Y. (1977) A three-group classification of rat retinal ganglion cells: histological and physiological studies. Brain Res., 119, 327-344.
14. 2+-free solutions in rat cortical neurons in vitro. J. Neurochem., 68, 1836-1845.
15. A channel subtypes. Mol. Neurobiol., 18, 35-86.
16. Kandler, K., Givens, R. & Katz, L.C. (1999) Photostimulation with caged glutamate. In Yuste, R., Lanni, F. & Konnerth, A. (Eds), Imaging Neurons: a Laboratory Manual. Cold Spring Harbor Laboratory Press, New York, pp. 27.1-27.9.
17. Klausberger, T., Sarto, L., Ehya, N., Fuchs, K., Furtmuller, R., Mayer, B., Huck, S. & Seighart, W. (2001) Alternate use of distinct intersubunit contacts controls GABAA receptor assembly and stoichiometry. J. Neurosci., 21, 9124-9133.
18. Leszkiewicz, D.N. & Aizenman, E. (2002) A role for the redox site in the modulation of the NMDA receptor by light. J. Physiol. (Lond.), 545, 435-440.
19. Leszkiewicz, D.N., Kandler, K. & Aizenman, E. (2000) Enhancement of NMDA receptor-mediated currents by light in rat neurones in vitro. J. Physiol. (Lond.), 524, 365-374.
20. Leszkiewicz, D.N., McLaughlin, B.A. & Aizenman, E. (2002) Protein kinases and light: unlikely partners in a receptor localization puzzle. Physiol. Behav., 77, 533-536.
21. Middendorf, T.R., Aldrich, R.W. & Baylor, D.A. (2000) Modification of cyclic nucleotide-gated ion channels by ultraviolet light. J. Gen. Physiol., 116, 227-252.
22. Nag, T.C. & Wadhwa, S. (1997) Expression of GABA in the fetal, postnatal, and adult human retinas: an immunohistochemical study. Vision Neurosci., 14, 425-432.
23. Pan, Z.H., Bahring, R., Grantyn, R. & Lipton, S.A. (1995) Differential modulation by sulhydryl redox agents and glutathione of GABA- and glycine-evoked currents in rat retinal ganglion cells. J. Neurosci., 15, 1384-1391.
24. A receptors. Neuroscience, 98, 333-338.
25. Perry, V.H. (1979) The ganglion cell layer of the retina of the rat: a Golgi study. Proc. Royal Soc. B., 204, 363-375.
26. Prompers, J.J., Hilbers, C.W. & Pepermans, H.A. (1999) Tryptophan mediated photoreduction of disulfide bond causes unusual fluorescence behaviour of Fusarium solani pisi cutinase. FEBS Letters, 456, 409-416.
27. A receptor subtypes. Pharmacol. Rev., 47, 181-234.
28. Sullivan, J.M., Traynelis, S.F., Chen, H.S., Escobar, W., Heinemann, S.F. & Lipton, S.A. (1994) Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor. Neuron, 13, 929-936.
29. Tang, L.H. & Aizenman, E. (1993) The modulation of N-methyl-D-aspartate receptors by redox and alkylating reagents in rat cortical neurones in vitro. J. Physiol. (Lond.), 465, 303-323.
30. Vanhooren, A., Devreese, B., Vanhee, K., Van Beeumen, J. & Hanssens, I. (2002) Photoexcitation of tryptophan groups induces reduction of two disulfide bonds in goat alpha-lactalbumin. Biochemistry, 41, 11035-11043.
31. Vladimirov, Y.A., Roshchupkin, D.I. & Fesenko, E.E. (1970) Photochemical reactions in amino acid residues and inactivation of enzymes during U.V.-irradiation. Photochemistry and Photobiology, 11, 227-246.
32. Wade, P.D., Taylor, J. & Siekevitz, P. (1988) Mammalian cerebral cortical tissue responds to low-intensity visible light. Proceedings of the National Academy of Sciences (USA), 85, 9322-9326.
33. 2+ complexation. Neuropharmacology, 43, 938-944.