Total vascular exclusion of the liver enhances the efficacy of retroviral-mediated associated thymidine kinase and interleukin-2 genes transfer against multiple hepatic tumors in rats

Surgery

Volumn 133, Issue 6, 2003, Pages 669-677

  Alves, Arnaud ^b   Charre, Lionel ^b   Panis, Yves ^a   Cardoso, Jorge ^b   Fabre, Monique ^b   Brisson, Edith ^b   Houssin, Didier ^b   Soubrane, Olivier ^b   Klatzmann, David ^b  

^a HÔPITAL LARIBOISIÈRE   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; GANCICLOVIR; INTERLEUKIN 2; RETROVIRUS VECTOR; THYMIDINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; GENE TRANSFER; GENETIC CODE; HERPES SIMPLEX VIRUS 1; LIVER TUMOR; MALE; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; RAT; SUICIDE GENE THERAPY; SURVIVAL RATE; TREATMENT OUTCOME; TUMOR REGRESSION; TUMOR VOLUME; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

EID: 0037782106     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1067/msy.2003.152     Document Type: Article

References (39)

1. Faivre J, Rat P, Arveux P. Epidémiologie des métastases hépatiques des cancers colorectaux. In: Nordlinger B, Jaeck D, editors. Traitement des métastases hépatiques des cancers colorectaux. Paris: Springer-Verlag; 1999. p. 3-9.
2. Scheele J, Stangl R, Alterndorf-Hofmann A. Hepatic metastases from colorectal carcinoma: impact of surgical resection on the natural history. Br J Surg 1990;77:1901-16.
3. Carroll NM, Tanabe KK. Gene therapy for liver tumors. Surg Oncol Clin North Am 1998;7:617-96.
4. Caruso M, Panis Y, Gagandeep S, Houssin D, Salzmann JL, Klatzmann D. Regression of an established macroscopic liver metastases after in situ transduction of a suicide gene. Proc Natl Acad Sci U S A 1993;90:7024-8.
5. Kianmanesh AR, Perrin H, Panis Y, Fabre M, Nagy HJ, Houssin D, et al. A distant bystander effect of suicide gene therapy: regression of nontransduced tumors together with a distant transduced tumor. Hum Gene Ther 1997;8:1807-14.
6. Freeman SM, Ramesh R, Shastri M, Munshi A, Jensen AK, Marrogi AJ. The role of cytokines in mediating the bystander effect using HSV-TK xenogeneic cells. Cancer Lett 1995;92:167-74.
7. Rosenberg SA, Lotze MT, Yang JE, Aebersold PM, Line Han WM, Seipp CA, et al. Experience with the use of high dose IL2 in the treatment of 652 cancer patients. Ann Surg 1989;210:474-85.
8. Chen S-H, Chen XHL, Wang Y, Kosai KI, Finegold MI, Rich SS, et al. Combination gene therapy for liver metastases of colon carcinoma in vivo. Proc Natl Acad Sci U S A 1995;92:2577-81.
9. Shiratori Y, Kanai F, Hikiba Y, Moriyama H, Hamada H, Matsumara M, et al. Gene therapy for hepatic micrometastases of murine colon carcinoma. J Hepatol 1998;28:886-95.
10. Yoshida H, Enomoto H, Tagawa M, Takenaga K, Tasaki K, Nakagawara A, et al. Impaired tumorigenicity and decreased liver metastases of murine neuroblastoma cells engineered to secrete interleukin-2 or granulocyte macrophage colony-stimulating factor. Cancer Gene Ther 1998;5:67-73.
11. Kwong YL, Chen SH, Kosai K, Finegold M, Woo SLC. Combination therapy with suicide and cytokine genes for hepatic metastases of lung cancer. Chest 1997;112:1332-7.
12. Jarnagin WR, Delman K, Kooby D, Mastorides S, Zager J, Brennan ME et al. Neoadjuvant interleukin-12 immunogene therapy protect against cancer recurrence after liver resection in an animal model. Ann Surg 2000;331:762-71.
13. Martinet O, Ermekova V, Qiao JQ, Sauter B, Mandeli J, Chen L, et al. Immunomodulatory gene therapy with interleukine 12 and 4-1BB ligand: long-term remission of liver metastases in a mouse model. J Natl Cancer Inst 2000;92:931-6.
14. Pham-Nguyen KB, Yang W, Saxena R, Thung SN, Woo SLC, Chen S-H. Role of NK and T cells in IL-12-induced antitumor response against hepatic colon carcinoma. Int J Cancer 1999;81:813-9.
15. Weber SM, Shi F, Heise C, Warner T, Mahvi DM. Interleukin-12 gene transfer result in CD8-dependent regression of murine CT26 liver tumors. Ann Surg Oncol 1999;6:186-94.
16. Hurford RK, Dranoff G, Mulligan RC, Tepper RI. Gene therapy of metastatic cancer by in vivo retroviral gene targeting. Nat Genet 1995;10:430-5.
17. Chen S-H, Kosai K-I, Xu B, Pham-Nguyen K, Contant C, Finegold MJ, et al. Combination suicide and cytokine gene therapy for hepatic metastases of colon carcinoma: sustained antitumor immunity prolongs animal survival. Cancer Res 1996;56:3758-62.
18. Panis Y, Ribeiro J, Chretien Y, Nordlinger B. Dormant liver metastases: an experimental study. Br J Surg 1992;79:221-3.
19. Bismuth H, Castaing D, Garden J. Major hepatic resection under total vascular exclusion. Ann Surg 1989;210:13-9.
20. Huguet C, Addario-Chieco P, Gavelli A, Arrigo E, Harb J, Clement RR. Technique of hepatic vascular exclusion of extensive liver resection. Am J Surg 1992;163:602-5.
21. Alexander HR, Bartlett DL, Libutti SK, Fraker DL Moser T, Rosenberg SA: Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver. J Clin Oncol 1998;16:1479-89.
22. Oldhafer KJ, Lang H, Frerker M, Moreno L, Chavan A, Flemming, et al. First experience and technical aspects of isolated liver perfusion for extensive liver metastases. Surgery 1998;123:622-31.
23. Martin F, Caignard A, Jeannin JF, Leclerc A, Martin M. Selection by trypsin of two sublines of rat colon cancer cells forming progressive or regressive tumors. Int J Cancer 1983;32:623-7.
24. Shimizu T, Pelletier H, Hammann A, Olsson NO, Martin MS, Mart F. Effect of single injection of anti-asialo GM1 serum on natural cytotoxicity and the growth of a regressive colonic tumor in syngenic rats. Int J Cancer 1987;40:676-80.
25. Klatzmann D, Valery CA, Bensimon G, Marro B, Boyer O, Mokhtari K, et al. A phase I/II study of herpes simplex virus type I thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy of Glioblastoma. Hum Gene Ther 1998;9:2595-604.
26. Klatzmann D, Cherin P, Bensimon G, Boyer O, Coutellier A, Charlotte F, et al. A phase I/II dose escalation study of herpes simplex virus type I thymidine kinase "suicide" gene therapy for metastatic melanoma. Study Group on Gene Therapy of Metastatic melanoma. Hum Gene Ther 1998;9:2585-94.
27. Brooks AD, Ba BNG, Brownlee M, Brownlee M, Burt M, Federoff HJ, et al. Specific organ gene transfer in vivo by regional organ perfusion with herpes viral amplicon vectors: implications for local gene therapy. Surgery 2001;129:324-34.
28. Carlsson G Gullberg B, Hafström L. Estimations of liver tumor volume using different formulas. An experimental study in rats. J Cancer Res Clin Oncol 1983;105:20-3.
29. Chant MF, Puhlmann M, Bartlett DL, Alexander HR Jr. Regional versus systemic delivery of recombinant vaccinia virus as suicide gene therapy for routine liver metastases. Ann Surg 1999;230:352-60.
30. De Roos WK, Fallaux FJ, Marinelli AWKS, Lazaris-Karatzas A, Alting von Geusau B, van der Eb MM, et al. Isolated-organ perfusion for local gene delivery: efficient adenovirus-mediated gene transfer into the liver. Gene Ther 1997;4:55-62.
31. Van der Eb MM, Cramer SJ, Vergouwe Y, Schagen FHE, van Krieken JHJM, van der Eb AJ, et al. Severe hepatic dysfunction after adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene and ganciclovir administration. Gene Ther 1998;5:451-8.
32. Brand K, Arnold W, Bartels T, Lieber A, Kay MA, Strauss M, et al. Liver-associated toxicity of the HSV-tk/GCV approach and adenoviral vectors. Cancer Gene Ther 1997;4:9-16.
33. Miller DG, Adam MA, Miller AD. Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol Cell Biol 1990;10:4239-42.
34. Dalgleish AG. The role of IL-2 in gene therapy. Gene Ther 1994;1:83-7.
35. Zager JS, Delman KA, Malhotra S, Ebright MI, Bennett JJ, Kates T, et al. Combination vascular delivery of herpes simplex oncolytic viruses and amplicon mediated cytokine gene transfer is effective therapy for experimental liver cancer. Mol Med 2001;7:561-8.
36. Paku S, Lapis K. Morphological aspects of angiogenesis in experimental liver metastases. Am J Pathol 1993;143:926-36.
37. Maron DJ, Tada H, Moscioni AD, Tazelaar J, Fraker DL, Wilson JM, et al. Intra-arterial delivery of a recombinant adenovirus does not increase gene transfer to tumor cells in a rat model of metastatic colorectal carcinoma. Mol Ther 2001;4:29-35.
38. Gerolami R, Cardoso J, Lewin M, Bralet MP, Sa Cunha A, Clément O. Evaluation of HSV-TK gene therapy in a rat model of chemically induced hepatocellular carcinoma by intratumoral and intrahepatic artery routes. Cancer Res 2000;60:993-1000.
39. Bilbao R, Gerolami R, Bralet ME Qian C, Tran PL, Tennant B, et al. Transduction efficacy, antitumoral effect, and toxicity of adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir therapy of hepatocellular carcinoma: the woodchuck animal model. Cancer Gene Ther 2000;7:657-62.